(44 nodes) Regulation of double-strand break repair via homologous recombination network (Oryzias latipes)

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second shell of interactors

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proteins of unknown 3D structure

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Predicted Interactions

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Your Input:
	helq	Helicase, POLQ like. (985 aa)
	trrap	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (3817 aa)
	ercc6	Excision repair cross-complementation group 6. (1342 aa)
	ENSORLP00000041690	Uncharacterized protein. (81 aa)
	mrgbp	MRG/MORF4L binding protein. (230 aa)
	LOC101155065	Enhancer of polycomb homolog. (966 aa)
	fbh1	F-box DNA helicase 1. (1070 aa)
	setd2	SET domain containing 2, histone lysine methyltransferase. (2587 aa)
	ENSORLP00000036835	Uncharacterized protein. (79 aa)
	wrap53	WD repeat containing, antisense to TP53. (467 aa)
	tp53bp1	Tumor protein p53 binding protein, 1. (1583 aa)
	fancb	FA complementation group B. (850 aa)
	timeless	Timeless circadian clock. (1244 aa)
	ENSORLP00000031850	Uncharacterized protein. (396 aa)
	rad51ap1	RAD51 associated protein 1. (315 aa)
	pogz	Pogo transposable element derived with ZNF domain a. (1271 aa)
	parpbp	PARP1 binding protein. (583 aa)
	ENSORLP00000028345	Bromo domain-containing protein. (263 aa)
	LOC101175681	Enhancer of polycomb homolog. (823 aa)
	terf2ip	Uncharacterized protein. (682 aa)
	Rif1	Uncharacterized protein. (1520 aa)
	H2N2X6_ORYLA	Pogo transposable element derived with ZNF domain b. (1647 aa)
	mms19	MMS19 homolog, cytosolic iron-sulfur assembly component. (1109 aa)
	rad51	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (396 aa)
	SPIDR	Scaffold protein involved in DNA repair. (885 aa)
	LOC110015669	Uncharacterized protein. (183 aa)
	hdgfl2	PWWP domain-containing protein. (612 aa)
	sirt6	Sirtuin 6. (347 aa)
	yeats4	YEATS domain containing 4. (226 aa)
	parp1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1015 aa)
	kdm1a	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (860 aa)
	recql5	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (989 aa)
	wdr48	WD repeat domain 48b. (677 aa)
	H2M6M6_ORYLA	Structural maintenance of chromosomes flexible hinge domain containing 1. (1384 aa)
	arid2	AT rich interactive domain 2 (ARID, RFX-like). (1631 aa)
	radx	RPA1 related single stranded DNA binding protein. (815 aa)
	LOC101157161	Zgc:101810; Belongs to the actin family. (394 aa)
	chek1	Checkpoint kinase 1; Belongs to the protein kinase superfamily. (454 aa)
	dmap1	DNA methyltransferase 1 associated protein 1. (484 aa)
	pias4	Protein inhibitor of activated STAT, 4a. (503 aa)
	rmi2	RecQ mediated genome instability 2. (140 aa)
	vps72	Vacuolar protein sorting 72 homolog a. (361 aa)
	shld2	Si:ch211-134m17.9. (721 aa)
	actr2	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (394 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSORLP00000028345	ENSORLP00000036835	ENSORLP00000028345	ENSORLP00000036835	Bromo domain-containing protein.	Uncharacterized protein.	0.811
ENSORLP00000028345	ENSORLP00000041690	ENSORLP00000028345	ENSORLP00000041690	Bromo domain-containing protein.	Uncharacterized protein.	0.866
ENSORLP00000028345	LOC101155065	ENSORLP00000028345	ENSORLP00000040597	Bromo domain-containing protein.	Enhancer of polycomb homolog.	0.784
ENSORLP00000028345	LOC101175681	ENSORLP00000028345	ENSORLP00000027888	Bromo domain-containing protein.	Enhancer of polycomb homolog.	0.784
ENSORLP00000028345	dmap1	ENSORLP00000028345	ENSORLP00000006828	Bromo domain-containing protein.	DNA methyltransferase 1 associated protein 1.	0.865
ENSORLP00000028345	mrgbp	ENSORLP00000028345	ENSORLP00000041503	Bromo domain-containing protein.	MRG/MORF4L binding protein.	0.909
ENSORLP00000028345	trrap	ENSORLP00000028345	ENSORLP00000042766	Bromo domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.906
ENSORLP00000028345	vps72	ENSORLP00000028345	ENSORLP00000003951	Bromo domain-containing protein.	Vacuolar protein sorting 72 homolog a.	0.734
ENSORLP00000028345	yeats4	ENSORLP00000028345	ENSORLP00000017403	Bromo domain-containing protein.	YEATS domain containing 4.	0.813
ENSORLP00000031850	chek1	ENSORLP00000031850	ENSORLP00000007199	Uncharacterized protein.	Checkpoint kinase 1; Belongs to the protein kinase superfamily.	0.678
ENSORLP00000031850	fbh1	ENSORLP00000031850	ENSORLP00000040243	Uncharacterized protein.	F-box DNA helicase 1.	0.527
ENSORLP00000031850	mms19	ENSORLP00000031850	ENSORLP00000025202	Uncharacterized protein.	MMS19 homolog, cytosolic iron-sulfur assembly component.	0.810
ENSORLP00000031850	parp1	ENSORLP00000031850	ENSORLP00000017176	Uncharacterized protein.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.439
ENSORLP00000031850	rad51	ENSORLP00000031850	ENSORLP00000022299	Uncharacterized protein.	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	0.741
ENSORLP00000031850	rad51ap1	ENSORLP00000031850	ENSORLP00000031362	Uncharacterized protein.	RAD51 associated protein 1.	0.539
ENSORLP00000031850	recql5	ENSORLP00000031850	ENSORLP00000015387	Uncharacterized protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.636
ENSORLP00000031850	rmi2	ENSORLP00000031850	ENSORLP00000006136	Uncharacterized protein.	RecQ mediated genome instability 2.	0.620
ENSORLP00000031850	terf2ip	ENSORLP00000031850	ENSORLP00000026778	Uncharacterized protein.	Uncharacterized protein.	0.539
ENSORLP00000031850	timeless	ENSORLP00000031850	ENSORLP00000032052	Uncharacterized protein.	Timeless circadian clock.	0.403
ENSORLP00000031850	wrap53	ENSORLP00000031850	ENSORLP00000036598	Uncharacterized protein.	WD repeat containing, antisense to TP53.	0.727