STRINGSTRING
angpt2 angpt2 LOC101173933 LOC101173933 fgf4 fgf4 LOC101174854 LOC101174854 H2L4B7_ORYLA H2L4B7_ORYLA Mtor Mtor LOC101157631 LOC101157631 gata2 gata2 Fgf1 Fgf1 LOC101159013 LOC101159013 map2k5 map2k5 vegfc vegfc LOC101155037 LOC101155037 fgf7 fgf7 ARSB ARSB rin2 rin2 bmpr2 bmpr2 rreb1 rreb1 LOC101175393 LOC101175393 atp5f1b atp5f1b LOC101160076 LOC101160076 LOC101156275 LOC101156275 LOC101175004 LOC101175004 LOC101169376 LOC101169376 LOC101154790 LOC101154790 agt agt LOC101166779 LOC101166779 LOC101161650 LOC101161650 fgf16 fgf16 tbxa2r tbxa2r LOC101161391 LOC101161391 LOC101166150 LOC101166150 glipr2 glipr2 ptk2b ptk2b pik3cg pik3cg ZC3H12A ZC3H12A lgmn lgmn angpt1 angpt1 LOC101172593 LOC101172593 dusp10 dusp10 LOC101158957 LOC101158957 tsta3 tsta3 LOC101173369 LOC101173369 LOC101167946 LOC101167946 rgcc rgcc LOC101165149 LOC101165149 sirt1 sirt1 APOH APOH APOH-2 APOH-2 LOC101161673 LOC101161673 sash1 sash1 LOC101170545 LOC101170545 H2MJT0_ORYLA H2MJT0_ORYLA itgb1bp1 itgb1bp1 bmper bmper bmp10 bmp10 plcg2 plcg2 LOC100049397 LOC100049397 H2MN86_ORYLA H2MN86_ORYLA VASH1 VASH1 nfe2l2 nfe2l2 LOC101160956 LOC101160956 H2MY81_ORYLA H2MY81_ORYLA met met ptprg ptprg Nf1 Nf1 plpp3 plpp3 pdgfb pdgfb LOC101171463 LOC101171463 gpi gpi vash2 vash2 efna1 efna1 meox2 meox2 ctsh ctsh LOC101167443 LOC101167443 vegfa vegfa LOC101162652 LOC101162652 plcg1 plcg1 LOC101172478 LOC101172478 ENSORLP00000032568 ENSORLP00000032568 ENSORLP00000032968 ENSORLP00000032968 LOC100301586 LOC100301586 sp1 sp1 LOC111948169 LOC111948169 LOC101165913 LOC101165913 LOC101167197 LOC101167197 mst1r mst1r ushbp1 ushbp1 LOC101166327 LOC101166327 aamp aamp ENSORLP00000036607 ENSORLP00000036607 rab25 rab25 capn7 capn7 ptpn23 ptpn23 LOC101169804 LOC101169804 fgf18 fgf18 glul glul ptk2 ptk2 LOC101171872 LOC101171872 LOC101163115 LOC101163115 LOC101157715 LOC101157715 LOC101174785 LOC101174785 LOC101175433 LOC101175433 TGFBR2 TGFBR2 nrp1 nrp1 LOC105356122 LOC105356122 LOC105357487 LOC105357487 LOC101165277 LOC101165277 cib1 cib1 CARD10 CARD10 LOC101166399 LOC101166399 LOC101167186 LOC101167186 bcas3 bcas3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
angpt2Angiopoietin 2a. (492 aa)
LOC101173933Glucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (188 aa)
LOC101174854Uncharacterized protein. (978 aa)
H2L4B7_ORYLAMechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (737 aa)
MtorSerine/threonine-protein kinase TOR. (1023 aa)
LOC101157631Transforming growth factor beta; Belongs to the TGF-beta family. (444 aa)
gata2Transcription factor GATA-2. (455 aa)
Fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (159 aa)
LOC101159013Si:rp71-17i16.5; Belongs to the PI3/PI4-kinase family. (1106 aa)
map2k5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (445 aa)
vegfcPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (494 aa)
LOC101155037Transforming growth factor beta; Belongs to the TGF-beta family. (420 aa)
fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (205 aa)
ARSBArylsulfatase B. (520 aa)
rin2Si:ch211-85n16.4. (996 aa)
bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1056 aa)
rreb1Ras responsive element binding protein 1a. (1807 aa)
LOC101175393Macrophage stimulating 1 receptor a. (1366 aa)
atp5f1bATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (517 aa)
LOC101160076ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (551 aa)
LOC101156275Si:dkey-174i8.1. (574 aa)
LOC101175004Arylsulfatase family, member Ia. (568 aa)
LOC101169376ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (592 aa)
LOC101154790Angiopoietin 2b. (506 aa)
agtAngiotensinogen; Belongs to the serpin family. (460 aa)
LOC101166779Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (949 aa)
LOC101161650Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (157 aa)
fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
tbxa2rThromboxane A2 receptor. (352 aa)
LOC101161391GATA binding protein 2a. (460 aa)
LOC101166150Heat shock protein, alpha-crystallin-related, b15; Belongs to the small heat shock protein (HSP20) family. (198 aa)
glipr2GLI pathogenesis-related 2, like; Belongs to the CRISP family. (156 aa)
ptk2bProtein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (995 aa)
pik3cgPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1121 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (270 aa)
lgmnLegumain. (434 aa)
angpt1Angiopoietin 1. (530 aa)
LOC101172593Tumor necrosis factor a (TNF superfamily, member 2). (279 aa)
dusp10Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (472 aa)
LOC101158957RAB25, member RAS oncogene family a. (211 aa)
tsta3Tissue specific transplantation antigen P35B. (325 aa)
LOC101173369Junction plakoglobin a. (733 aa)
LOC1011679461-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1225 aa)
rgccRegulator of cell cycle. (154 aa)
LOC101165149Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (510 aa)
sirt1Deacetylase sirtuin-type domain-containing protein. (680 aa)
APOHUncharacterized protein. (364 aa)
APOH-2Apolipoprotein H. (362 aa)
LOC101161673Apolipoprotein Eb. (265 aa)
sash1SAM and SH3 domain containing 1a. (1225 aa)
LOC101170545Zinc finger CCCH-type containing 12A. (621 aa)
H2MJT0_ORYLAUncharacterized protein. (589 aa)
itgb1bp1Integrin beta 1 binding protein 1. (198 aa)
bmperBMP binding endothelial regulator. (683 aa)
bmp10Bone morphogenetic protein 10. (488 aa)
plcg21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1247 aa)
LOC100049397Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals; Belongs to the metallothionein superfamily. Type 1 family. (60 aa)
H2MN86_ORYLAADP-ribosylation factor 6b. (112 aa)
VASH1Vasohibin 1. (335 aa)
nfe2l2Nuclear factor, erythroid 2-like 2a. (605 aa)
LOC101160956JunE proto-oncogene, AP-1 transcription factor subunit. (425 aa)
H2MY81_ORYLAFERM_N_2 domain-containing protein. (84 aa)
metMET proto-oncogene, receptor tyrosine kinase. (1403 aa)
ptprgCarbonic anhydrase XVI b. (1050 aa)
Nf1Uncharacterized protein. (506 aa)
plpp3Phospholipid phosphatase 3. (332 aa)
pdgfbPlatelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (553 aa)
LOC101171463Angiopoietin 4. (516 aa)
gpiGlucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
vash2Vasohibin 2. (371 aa)
efna1Ephrin-A1b; Belongs to the ephrin family. (263 aa)
meox2Mesenchyme homeobox 2a. (366 aa)
ctshCathepsin H; Belongs to the peptidase C1 family. (324 aa)
LOC101167443Si:ch211-191a24.4. (282 aa)
vegfaVascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (214 aa)
LOC101162652FERM domain-containing protein. (274 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1311 aa)
LOC101172478Arylsulfatase family, member J. (597 aa)
ENSORLP00000032568Fibroblast growth factor binding protein 1b. (196 aa)
ENSORLP00000032968Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (287 aa)
LOC100301586CD40 molecule, TNF receptor superfamily member 5. (305 aa)
sp1Sp1 transcription factor. (467 aa)
LOC111948169Ephrin-A1a; Belongs to the ephrin family. (222 aa)
LOC101165913EMI domain-containing protein. (800 aa)
LOC101167197Si:ch211-191a24.4. (360 aa)
mst1rMacrophage stimulating 1 receptor b. (1372 aa)
ushbp1Usher syndrome 1C binding protein 1. (693 aa)
LOC101166327Si:dkey-175m17.7. (881 aa)
aampAngio-associated, migratory cell protein. (417 aa)
ENSORLP00000036607Uncharacterized protein. (251 aa)
rab25RAB25, member RAS oncogene family b. (305 aa)
capn7Calpain 7; Belongs to the peptidase C2 family. (824 aa)
ptpn23Protein tyrosine phosphatase, non-receptor type 23, a. (1885 aa)
LOC101169804Epithelial cell adhesion molecule. (386 aa)
fgf18Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
glulGlutamine synthetase. (371 aa)
ptk2Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1119 aa)
LOC101171872ADAM metallopeptidase domain 17a. (850 aa)
LOC101163115SH3-domain binding protein 1. (756 aa)
LOC101157715Bone morphogenetic protein 10, like. (441 aa)
LOC101174785TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (587 aa)
LOC101175433Sulfatase domain-containing protein. (753 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (540 aa)
nrp1Neuropilin; Belongs to the neuropilin family. (938 aa)
LOC105356122Uncharacterized protein. (1405 aa)
LOC105357487Activin_recp domain-containing protein. (762 aa)
LOC101165277ADAM metallopeptidase domain 17b. (844 aa)
cib1Calcium and integrin binding 1 (calmyrin). (189 aa)
CARD10Caspase recruitment domain family member 10. (1012 aa)
LOC101166399Apolipoprotein Ea. (262 aa)
LOC101167186Methyl CpG binding protein 2. (1004 aa)
bcas3BCAS3 microtubule associated cell migration factor. (948 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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