STRINGSTRING
H2L4B7_ORYLA H2L4B7_ORYLA LOC101158957 LOC101158957 lgmn lgmn ZC3H12A ZC3H12A pik3cg pik3cg glipr2 glipr2 LOC101166150 LOC101166150 LOC101161391 LOC101161391 fgf16 fgf16 LOC101161650 LOC101161650 agt agt LOC101169376 LOC101169376 LOC101160076 LOC101160076 atp5f1b atp5f1b LOC101175393 LOC101175393 rreb1 rreb1 bmpr2 bmpr2 rin2 rin2 fgf7 fgf7 LOC101155037 LOC101155037 vegfc vegfc LOC101159013 LOC101159013 Fgf1 Fgf1 gata2 gata2 LOC101157631 LOC101157631 Mtor Mtor tsta3 tsta3 LOC101174854 LOC101174854 LOC101173933 LOC101173933 bcas3 bcas3 cib1 cib1 LOC101165277 LOC101165277 LOC105357487 LOC105357487 LOC105356122 LOC105356122 nrp1 nrp1 TGFBR2 TGFBR2 LOC101174785 LOC101174785 LOC101171872 LOC101171872 fgf18 fgf18 capn7 capn7 rab25 rab25 ENSORLP00000036607 ENSORLP00000036607 aamp aamp mst1r mst1r sp1 sp1 LOC100301586 LOC100301586 ENSORLP00000032968 ENSORLP00000032968 ENSORLP00000032568 ENSORLP00000032568 plcg1 plcg1 vegfa vegfa ctsh ctsh gpi gpi pdgfb pdgfb plpp3 plpp3 met met LOC101160956 LOC101160956 nfe2l2 nfe2l2 H2MN86_ORYLA H2MN86_ORYLA LOC100049397 LOC100049397 plcg2 plcg2 itgb1bp1 itgb1bp1 LOC101170545 LOC101170545 sash1 sash1 sirt1 sirt1 LOC101165149 LOC101165149 LOC101167946 LOC101167946
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H2L4B7_ORYLAMechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (737 aa)
LOC101158957RAB25, member RAS oncogene family a. (211 aa)
lgmnLegumain. (434 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (270 aa)
pik3cgPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1121 aa)
glipr2GLI pathogenesis-related 2, like; Belongs to the CRISP family. (156 aa)
LOC101166150Heat shock protein, alpha-crystallin-related, b15; Belongs to the small heat shock protein (HSP20) family. (198 aa)
LOC101161391GATA binding protein 2a. (460 aa)
fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
LOC101161650Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (157 aa)
agtAngiotensinogen; Belongs to the serpin family. (460 aa)
LOC101169376ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (592 aa)
LOC101160076ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (551 aa)
atp5f1bATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (517 aa)
LOC101175393Macrophage stimulating 1 receptor a. (1366 aa)
rreb1Ras responsive element binding protein 1a. (1807 aa)
bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1056 aa)
rin2Si:ch211-85n16.4. (996 aa)
fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (205 aa)
LOC101155037Transforming growth factor beta; Belongs to the TGF-beta family. (420 aa)
vegfcPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (494 aa)
LOC101159013Si:rp71-17i16.5; Belongs to the PI3/PI4-kinase family. (1106 aa)
Fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (159 aa)
gata2Transcription factor GATA-2. (455 aa)
LOC101157631Transforming growth factor beta; Belongs to the TGF-beta family. (444 aa)
MtorSerine/threonine-protein kinase TOR. (1023 aa)
tsta3Tissue specific transplantation antigen P35B. (325 aa)
LOC101174854Uncharacterized protein. (978 aa)
LOC101173933Glucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
bcas3BCAS3 microtubule associated cell migration factor. (948 aa)
cib1Calcium and integrin binding 1 (calmyrin). (189 aa)
LOC101165277ADAM metallopeptidase domain 17b. (844 aa)
LOC105357487Activin_recp domain-containing protein. (762 aa)
LOC105356122Uncharacterized protein. (1405 aa)
nrp1Neuropilin; Belongs to the neuropilin family. (938 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (540 aa)
LOC101174785TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (587 aa)
LOC101171872ADAM metallopeptidase domain 17a. (850 aa)
fgf18Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
capn7Calpain 7; Belongs to the peptidase C2 family. (824 aa)
rab25RAB25, member RAS oncogene family b. (305 aa)
ENSORLP00000036607Uncharacterized protein. (251 aa)
aampAngio-associated, migratory cell protein. (417 aa)
mst1rMacrophage stimulating 1 receptor b. (1372 aa)
sp1Sp1 transcription factor. (467 aa)
LOC100301586CD40 molecule, TNF receptor superfamily member 5. (305 aa)
ENSORLP00000032968Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (287 aa)
ENSORLP00000032568Fibroblast growth factor binding protein 1b. (196 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1311 aa)
vegfaVascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (214 aa)
ctshCathepsin H; Belongs to the peptidase C1 family. (324 aa)
gpiGlucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
pdgfbPlatelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (553 aa)
plpp3Phospholipid phosphatase 3. (332 aa)
metMET proto-oncogene, receptor tyrosine kinase. (1403 aa)
LOC101160956JunE proto-oncogene, AP-1 transcription factor subunit. (425 aa)
nfe2l2Nuclear factor, erythroid 2-like 2a. (605 aa)
H2MN86_ORYLAADP-ribosylation factor 6b. (112 aa)
LOC100049397Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals; Belongs to the metallothionein superfamily. Type 1 family. (60 aa)
plcg21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1247 aa)
itgb1bp1Integrin beta 1 binding protein 1. (198 aa)
LOC101170545Zinc finger CCCH-type containing 12A. (621 aa)
sash1SAM and SH3 domain containing 1a. (1225 aa)
sirt1Deacetylase sirtuin-type domain-containing protein. (680 aa)
LOC101165149Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (510 aa)
LOC1011679461-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1225 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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