(71 nodes) Positive regulation of cell-substrate adhesion network (Oryzias latipes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101157076	Vitronectin b. (437 aa)
	lrrc45	Leucine rich repeat containing 45. (668 aa)
	LOC101168985	Testis associated actin remodelling kinase 2. (490 aa)
	dab2	DAB adaptor protein 2. (761 aa)
	rreb1	Ras responsive element binding protein 1a. (1807 aa)
	ILK	Integrin linked kinase. (452 aa)
	LOC101155756	LIM domain-containing protein. (335 aa)
	LOC101172012	Uncharacterized protein. (452 aa)
	H2LK26_ORYLA	Neuron-derived neurotrophic factor, like. (512 aa)
	LOC101164658	Uncharacterized protein. (242 aa)
	LOC101155377	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2. (432 aa)
	LOC101161346	Uncharacterized protein. (355 aa)
	tesk1	Si:dkeyp-75h12.2. (680 aa)
	LOC101170202	Vitronectin a. (554 aa)
	plekha2	Si:ch211-204d2.4. (431 aa)
	LOC101159101	Si:dkey-32e6.6. (638 aa)
	spock2	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2. (419 aa)
	cass4	Cas scaffold protein family member 4. (793 aa)
	crk	CRK proto-oncogene, adaptor protein. (315 aa)
	poldip2	Polymerase (DNA-directed), delta interacting protein 2. (375 aa)
	LOC101168044	Uncharacterized protein. (283 aa)
	LOC101168287	Colony stimulating factor 1b (macrophage). (301 aa)
	ccn1	Cellular communication network factor 1. (376 aa)
	crkl	V-crk avian sarcoma virus CT10 oncogene homolog-like. (306 aa)
	c1qbp	Complement component 1, q subcomponent binding protein. (292 aa)
	CDC42	Cell division cycle 42. (191 aa)
	tsta3	Tissue specific transplantation antigen P35B. (325 aa)
	LOC101173369	Junction plakoglobin a. (733 aa)
	disc1	DISC1 scaffold protein. (814 aa)
	LOC101165149	Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (510 aa)
	ccdc80	Coiled-coil domain containing 80. (840 aa)
	tsc1	TSC complex subunit 1b. (1198 aa)
	rin2	Si:ch211-85n16.4. (996 aa)
	LOC101175634	Myocilin. (570 aa)
	emilin1	Uncharacterized protein. (1116 aa)
	itgb1bp1	Integrin beta 1 binding protein 1. (198 aa)
	LOC101164852	LIM domain-containing protein. (404 aa)
	LOC101169721	Apolipoprotein A-Ib. (323 aa)
	LOC101160037	Elastin microfibril interfacer 1a. (1027 aa)
	fn1	Fibronectin-1. (2503 aa)
	pdgfb	Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (553 aa)
	vwc2	Von Willebrand factor C domain containing 2. (347 aa)
	LOC101159689	EMI domain-containing protein. (440 aa)
	LOC101164657	Neural_ProG_Cyt domain-containing protein. (635 aa)
	LOC101169731	Si:dkeyp-66d1.7. (293 aa)
	LOC101174454	Uncharacterized protein. (191 aa)
	EGFLAM	EGF like, fibronectin type III and laminin G domains. (1063 aa)
	ENSORLP00000029637	Uncharacterized protein. (323 aa)
	vegfa	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (214 aa)
	LOC101167793	Zgc:77748. (283 aa)
	ENSORLP00000031311	Uncharacterized protein. (248 aa)
	emid1	Uncharacterized protein. (372 aa)
	LOC110016423	Uncharacterized protein. (313 aa)
	LOC101164400	Uncharacterized protein. (191 aa)
	fermt1	Fermitin family member 1. (665 aa)
	egfl6	EGF-like-domain, multiple 6. (542 aa)
	MYOC	Myocilin. (458 aa)
	ENSORLP00000039215	Uncharacterized protein. (1161 aa)
	nrp1	Neuropilin; Belongs to the neuropilin family. (938 aa)
	cspg5	Chondroitin sulfate proteoglycan 5a. (614 aa)
	arl2	ADP-ribosylation factor-like 2; Belongs to the small GTPase superfamily. Arf family. (184 aa)
	rsu1	Ras suppressor protein 1. (277 aa)
	LOC101166145	Uncharacterized protein. (683 aa)
	cib1	Calcium and integrin binding 1 (calmyrin). (189 aa)
	agr2	Anterior gradient 2. (164 aa)
	ECM2	Extracellular matrix protein 2. (668 aa)
	LOC101162278	Chemokine (C-C motif) ligand 25b. (96 aa)
	ndnf	Neuron-derived neurotrophic factor. (571 aa)
	LOC101155699	Protein S100; Belongs to the S-100 family. (96 aa)
	LOC101174854	Uncharacterized protein. (978 aa)
	LOC101158994	Protein kinase domain-containing protein. (670 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	ENSORLP00000031311	ENSORLP00000015084	ENSORLP00000031311	Cell division cycle 42.	Uncharacterized protein.	0.400
CDC42	LOC110016423	ENSORLP00000015084	ENSORLP00000033986	Cell division cycle 42.	Uncharacterized protein.	0.401
CDC42	crk	ENSORLP00000015084	ENSORLP00000012262	Cell division cycle 42.	CRK proto-oncogene, adaptor protein.	0.401
CDC42	crkl	ENSORLP00000015084	ENSORLP00000013917	Cell division cycle 42.	V-crk avian sarcoma virus CT10 oncogene homolog-like.	0.401
CDC42	tsc1	ENSORLP00000015084	ENSORLP00000018027	Cell division cycle 42.	TSC complex subunit 1b.	0.400
ENSORLP00000031311	CDC42	ENSORLP00000031311	ENSORLP00000015084	Uncharacterized protein.	Cell division cycle 42.	0.400
ENSORLP00000031311	LOC101164400	ENSORLP00000031311	ENSORLP00000034529	Uncharacterized protein.	Uncharacterized protein.	0.400
ENSORLP00000031311	LOC101164658	ENSORLP00000031311	ENSORLP00000007959	Uncharacterized protein.	Uncharacterized protein.	0.400
ENSORLP00000031311	LOC101174454	ENSORLP00000031311	ENSORLP00000028896	Uncharacterized protein.	Uncharacterized protein.	0.400
ENSORLP00000031311	nrp1	ENSORLP00000031311	ENSORLP00000042087	Uncharacterized protein.	Neuropilin; Belongs to the neuropilin family.	0.407
ENSORLP00000031311	tsc1	ENSORLP00000031311	ENSORLP00000018027	Uncharacterized protein.	TSC complex subunit 1b.	0.545
ILK	LOC101155756	ENSORLP00000005213	ENSORLP00000005743	Integrin linked kinase.	LIM domain-containing protein.	0.929
ILK	LOC101164852	ENSORLP00000005213	ENSORLP00000019454	Integrin linked kinase.	LIM domain-containing protein.	0.929
ILK	LOC101172012	ENSORLP00000005213	ENSORLP00000005819	Integrin linked kinase.	Uncharacterized protein.	0.900
ILK	fermt1	ENSORLP00000005213	ENSORLP00000035259	Integrin linked kinase.	Fermitin family member 1.	0.791
ILK	rsu1	ENSORLP00000005213	ENSORLP00000042454	Integrin linked kinase.	Ras suppressor protein 1.	0.906
LOC101155756	ILK	ENSORLP00000005743	ENSORLP00000005213	LIM domain-containing protein.	Integrin linked kinase.	0.929
LOC101155756	LOC101172012	ENSORLP00000005743	ENSORLP00000005819	LIM domain-containing protein.	Uncharacterized protein.	0.929
LOC101155756	fermt1	ENSORLP00000005743	ENSORLP00000035259	LIM domain-containing protein.	Fermitin family member 1.	0.540
LOC101155756	rsu1	ENSORLP00000005743	ENSORLP00000042454	LIM domain-containing protein.	Ras suppressor protein 1.	0.967