(23 nodes) Negative regulation of cell-substrate adhesion network (Oryzias latipes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H2L7K0_ORYLA	Thyroglobulin type-1 domain-containing protein. (232 aa)
	spry4	Sprouty homolog 4 (Drosophila). (378 aa)
	LOC101175634	Myocilin. (570 aa)
	LOC101172563	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family. (935 aa)
	nexmif	Neurite extension and migration factor b. (1490 aa)
	acer2	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (277 aa)
	tbcd	Tubulin folding cofactor D. (1195 aa)
	rasa1	RAS p21 protein activator (GTPase activating protein) 1a. (1055 aa)
	serpine1	SERPIN domain-containing protein; Belongs to the serpin family. (447 aa)
	fzd4	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (529 aa)
	H2MJT0_ORYLA	Uncharacterized protein. (589 aa)
	itgb1bp1	Integrin beta 1 binding protein 1. (198 aa)
	LOC101167075	Apolipoprotein Da, duplicate 1; Belongs to the calycin superfamily. Lipocalin family. (186 aa)
	Nf1	Uncharacterized protein. (506 aa)
	ap1ar	Adaptor related protein complex 1 associated regulatory protein. (306 aa)
	LOC101170718	Apolipoprotein Db; Belongs to the calycin superfamily. Lipocalin family. (232 aa)
	cask	Uncharacterized protein; Belongs to the MAGUK family. (954 aa)
	LOC101170232	Apolipoprotein Db; Belongs to the calycin superfamily. Lipocalin family. (195 aa)
	LOC101169001	Rho GTPase activating protein 6. (732 aa)
	LOC101169804	Epithelial cell adhesion molecule. (386 aa)
	MYOC	Myocilin. (458 aa)
	ajap1	Adherens junctions associated protein 1. (387 aa)
	bcas3	BCAS3 microtubule associated cell migration factor. (948 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H2MJT0_ORYLA	Nf1	ENSORLP00000018929	ENSORLP00000026133	Uncharacterized protein.	Uncharacterized protein.	0.943
H2MJT0_ORYLA	rasa1	ENSORLP00000018929	ENSORLP00000012485	Uncharacterized protein.	RAS p21 protein activator (GTPase activating protein) 1a.	0.690
LOC101172563	cask	ENSORLP00000006053	ENSORLP00000031235	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.	Uncharacterized protein; Belongs to the MAGUK family.	0.785
Nf1	H2MJT0_ORYLA	ENSORLP00000026133	ENSORLP00000018929	Uncharacterized protein.	Uncharacterized protein.	0.943
Nf1	rasa1	ENSORLP00000026133	ENSORLP00000012485	Uncharacterized protein.	RAS p21 protein activator (GTPase activating protein) 1a.	0.690
cask	LOC101172563	ENSORLP00000031235	ENSORLP00000006053	Uncharacterized protein; Belongs to the MAGUK family.	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.	0.785
rasa1	H2MJT0_ORYLA	ENSORLP00000012485	ENSORLP00000018929	RAS p21 protein activator (GTPase activating protein) 1a.	Uncharacterized protein.	0.690
rasa1	Nf1	ENSORLP00000012485	ENSORLP00000026133	RAS p21 protein activator (GTPase activating protein) 1a.	Uncharacterized protein.	0.690