(81 nodes) Positive regulation of endopeptidase activity network (Oryzias latipes)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	mbp	Myelin basic protein b. (237 aa)
	H2L4N6_ORYLA	Uncharacterized protein. (780 aa)
	uaca	Uveal autoantigen with coiled-coil domains and ankyrin repeats b. (1384 aa)
	LOC101170271	Nerve growth factor receptor a (TNFR superfamily, member 16). (389 aa)
	NCSTN	Nicastrin. (677 aa)
	LOC101167495	Un-named hu7910. (689 aa)
	psmd14	Proteasome 26S subunit, non-ATPase 14. (325 aa)
	f3	Coagulation factor IIIa. (284 aa)
	LOC101159282	Diablo, IAP-binding mitochondrial protein a. (249 aa)
	LOC101168213	BCL2 associated X, apoptosis regulator a. (188 aa)
	rad21	Uncharacterized protein. (636 aa)
	psme1	Proteasome activator subunit 1. (250 aa)
	LOC101168864	P53-induced death domain protein 1. (1004 aa)
	acer2	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (277 aa)
	LOC101174272-2	PRELI domain containing 1a. (210 aa)
	LOC105356557	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (393 aa)
	LOC101164818	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1252 aa)
	LOC101164095	Uncharacterized protein. (286 aa)
	sfrp2	Secreted frizzled-related protein 2. (290 aa)
	ripk2	Receptor-interacting serine-threonine kinase 2. (590 aa)
	pdcd5	Programmed cell death 5. (125 aa)
	lgmn	Legumain. (434 aa)
	aifm1	Apoptosis inducing factor mitochondrion associated 1. (708 aa)
	LOC101172593	Tumor necrosis factor a (TNF superfamily, member 2). (279 aa)
	pdcd2	Programmed cell death 2. (366 aa)
	ccn1	Cellular communication network factor 1. (376 aa)
	LOC101171428	FZ domain-containing protein. (337 aa)
	LOC100125536	Uncharacterized protein; Belongs to the peptidase C14A family. (389 aa)
	casp8	Uncharacterized protein; Belongs to the peptidase C14A family. (481 aa)
	akirin2	Akirin 2. (179 aa)
	tnfsf10	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (281 aa)
	casp2	Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (501 aa)
	psme2	Proteasome activator subunit 2. (241 aa)
	H2ME57_ORYLA	V-set immunoregulatory receptor. (288 aa)
	sirt1	Deacetylase sirtuin-type domain-containing protein. (680 aa)
	LOC101173147	RAD21 cohesin complex component like 1. (539 aa)
	LOC101171004	RPN13_C domain-containing protein. (417 aa)
	TFAP4	Transcription factor AP-4 (activating enhancer binding protein 4). (332 aa)
	cflar	FLICE-like inhibitory protein; Belongs to the peptidase C14A family. (460 aa)
	casp8ap2	Uncharacterized protein. (1602 aa)
	LOC101164618	CASP2 and RIPK1 domain containing adaptor with death domain. (203 aa)
	LOC101175629	Adhesion regulating molecule 1. (412 aa)
	prr7	Proline rich 7, synaptic. (253 aa)
	mul1	Mitochondrial E3 ubiquitin protein ligase 1b. (382 aa)
	sox7	Uncharacterized protein. (407 aa)
	LOC101156606	Asp-B-Hydro_N domain-containing protein. (601 aa)
	psme3	Proteasome activator subunit 3. (256 aa)
	LOC101160423	Ephrin-A3a; Belongs to the ephrin family. (224 aa)
	efna1	Ephrin-A1b; Belongs to the ephrin family. (263 aa)
	LOC101167651	Mitochondrial E3 ubiquitin protein ligase 1a. (376 aa)
	ctsh	Cathepsin H; Belongs to the peptidase C1 family. (324 aa)
	LOC101161579	Uncharacterized protein. (199 aa)
	LOC101170619	Uncharacterized protein. (184 aa)
	bad	BCL2 associated agonist of cell death b. (164 aa)
	ENSORLP00000030118	CARD domain-containing protein. (96 aa)
	LOC101172882	GRAM domain containing 4b. (539 aa)
	gramd4	GRAM domain containing 4a. (617 aa)
	LOC101164954	PRELI/MSF1 domain-containing protein. (221 aa)
	LOC111948169	Ephrin-A1a; Belongs to the ephrin family. (222 aa)
	LOC101167634	Coagulation factor II thrombin receptor. (440 aa)
	esco2	Uncharacterized protein. (530 aa)
	LOC101167461	NK3 homeobox 1. (188 aa)
	card9	Caspase recruitment domain family, member 9. (510 aa)
	diablo	Diablo, IAP-binding mitochondrial protein a. (267 aa)
	dap	Death-associated protein. (107 aa)
	hip1	Huntingtin interacting protein 1. (1099 aa)
	eif2ak3	Protein kinase domain-containing protein. (1094 aa)
	fas	Uncharacterized protein. (310 aa)
	st18	ST18 C2H2C-type zinc finger transcription factor. (1111 aa)
	LOC101158686	MALT paracaspase 2. (843 aa)
	LOC101168162	Uncharacterized protein. (177 aa)
	LOC101168687	Zgc:153993. (293 aa)
	LOC101159737	Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family. (269 aa)
	LOC101158194	MALT paracaspase 3. (557 aa)
	casp9	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (438 aa)
	arl6ip5	PRA1 family protein. (191 aa)
	efna3	Ephrin-A3b; Belongs to the ephrin family. (221 aa)
	fadd	Uncharacterized protein. (192 aa)
	LOC101171170	MALT paracaspase 1. (811 aa)
	LOC101175405	Transcription factor AP-4 (activating enhancer binding protein 4). (330 aa)
	ENSORLP00000045232	Uncharacterized protein. (178 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSORLP00000030118	H2L4N6_ORYLA	ENSORLP00000030118	ENSORLP00000000732	CARD domain-containing protein.	Uncharacterized protein.	0.736
ENSORLP00000030118	LOC100125536	ENSORLP00000030118	ENSORLP00000013993	CARD domain-containing protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.957
ENSORLP00000030118	LOC101161579	ENSORLP00000030118	ENSORLP00000029287	CARD domain-containing protein.	Uncharacterized protein.	0.900
ENSORLP00000030118	LOC101170619	ENSORLP00000030118	ENSORLP00000029756	CARD domain-containing protein.	Uncharacterized protein.	0.900
ENSORLP00000030118	casp8	ENSORLP00000030118	ENSORLP00000014046	CARD domain-containing protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.963
ENSORLP00000045232	H2L4N6_ORYLA	ENSORLP00000045232	ENSORLP00000000732	Uncharacterized protein.	Uncharacterized protein.	0.736
ENSORLP00000045232	LOC100125536	ENSORLP00000045232	ENSORLP00000013993	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.592
ENSORLP00000045232	casp8	ENSORLP00000045232	ENSORLP00000014046	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.650
H2L4N6_ORYLA	ENSORLP00000030118	ENSORLP00000000732	ENSORLP00000030118	Uncharacterized protein.	CARD domain-containing protein.	0.736
H2L4N6_ORYLA	ENSORLP00000045232	ENSORLP00000000732	ENSORLP00000045232	Uncharacterized protein.	Uncharacterized protein.	0.736
H2L4N6_ORYLA	LOC101161579	ENSORLP00000000732	ENSORLP00000029287	Uncharacterized protein.	Uncharacterized protein.	0.736
H2L4N6_ORYLA	LOC101170619	ENSORLP00000000732	ENSORLP00000029756	Uncharacterized protein.	Uncharacterized protein.	0.736
H2L4N6_ORYLA	fadd	ENSORLP00000000732	ENSORLP00000043356	Uncharacterized protein.	Uncharacterized protein.	0.414
H2L4N6_ORYLA	ripk2	ENSORLP00000000732	ENSORLP00000010554	Uncharacterized protein.	Receptor-interacting serine-threonine kinase 2.	0.435
LOC100125536	ENSORLP00000030118	ENSORLP00000013993	ENSORLP00000030118	Uncharacterized protein; Belongs to the peptidase C14A family.	CARD domain-containing protein.	0.957
LOC100125536	ENSORLP00000045232	ENSORLP00000013993	ENSORLP00000045232	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.592
LOC100125536	LOC101158194	ENSORLP00000013993	ENSORLP00000040489	Uncharacterized protein; Belongs to the peptidase C14A family.	MALT paracaspase 3.	0.625
LOC100125536	LOC101158686	ENSORLP00000013993	ENSORLP00000039932	Uncharacterized protein; Belongs to the peptidase C14A family.	MALT paracaspase 2.	0.625
LOC100125536	LOC101159282	ENSORLP00000013993	ENSORLP00000005325	Uncharacterized protein; Belongs to the peptidase C14A family.	Diablo, IAP-binding mitochondrial protein a.	0.494
LOC100125536	LOC101159737	ENSORLP00000013993	ENSORLP00000040434	Uncharacterized protein; Belongs to the peptidase C14A family.	Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family.	0.872