(19 nodes) Peptide hormone processing network (Oryzias latipes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101161187	P/Homo B domain-containing protein; Belongs to the peptidase S8 family. (573 aa)
	pcsk5	Proprotein convertase subtilisin/kexin type 5b; Belongs to the peptidase S8 family. (1878 aa)
	furin	Furin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family. (835 aa)
	pcsk6	Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (923 aa)
	corin	Corin, serine peptidase. (721 aa)
	ece1	Endothelin converting enzyme 1. (780 aa)
	LOC101173759	Metalloendopeptidase. (799 aa)
	LOC100049240	Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family. (814 aa)
	pcsk1	Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (765 aa)
	adam10	Uncharacterized protein. (747 aa)
	LOC101172489	ADAM metallopeptidase domain 10b. (784 aa)
	LOC111946416	Angiotensin-converting enzyme. (656 aa)
	H2LJC9_ORYLA	Proprotein convertase subtilisin/kexin type 5a. (1036 aa)
	LOC101160615	Metalloendopeptidase. (604 aa)
	ENSORLP00000043772	TNFR-Cys domain-containing protein. (288 aa)
	ace	Angiotensin-converting enzyme. (1306 aa)
	scg5	Secretogranin V. (280 aa)
	pcsk2	Proprotein convertase subtilisin/kexin type 2; Belongs to the peptidase S8 family. (641 aa)
	LOC101164289	Endothelin converting enzyme 2b. (789 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC100049240	LOC101164289	ENSORLP00000011461	ENSORLP00000033373	Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family.	Endothelin converting enzyme 2b.	0.463
LOC101161187	scg5	ENSORLP00000029984	ENSORLP00000038671	P/Homo B domain-containing protein; Belongs to the peptidase S8 family.	Secretogranin V.	0.404
LOC101164289	LOC100049240	ENSORLP00000033373	ENSORLP00000011461	Endothelin converting enzyme 2b.	Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family.	0.463
pcsk1	scg5	ENSORLP00000010803	ENSORLP00000038671	Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family.	Secretogranin V.	0.404
pcsk2	scg5	ENSORLP00000034584	ENSORLP00000038671	Proprotein convertase subtilisin/kexin type 2; Belongs to the peptidase S8 family.	Secretogranin V.	0.866
scg5	LOC101161187	ENSORLP00000038671	ENSORLP00000029984	Secretogranin V.	P/Homo B domain-containing protein; Belongs to the peptidase S8 family.	0.404
scg5	pcsk1	ENSORLP00000038671	ENSORLP00000010803	Secretogranin V.	Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family.	0.404
scg5	pcsk2	ENSORLP00000038671	ENSORLP00000034584	Secretogranin V.	Proprotein convertase subtilisin/kexin type 2; Belongs to the peptidase S8 family.	0.866