(49 nodes) Thiolester hydrolase activity network (Oryzias latipes)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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co-expression

protein homology

Your Input:
	LOC101161407	Hydroxyacylglutathione hydrolase. (309 aa)
	ppt1	Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile). (304 aa)
	pla2g6	Phospholipase A2, group VI (cytosolic, calcium-independent). (820 aa)
	mblac2	Metallo-beta-lactamase domain containing 2. (276 aa)
	abhd17b	Abhydrolase domain containing 17B. (288 aa)
	H2M6L1_ORYLA	Si:ch73-71c20.5. (150 aa)
	acot8	Acyl-CoA thioesterase 8. (337 aa)
	LOC101169644	Si:dkey-61p9.11. (2090 aa)
	olpks	Carrier domain-containing protein. (2051 aa)
	acot13	Acyl-CoA thioesterase 13. (142 aa)
	abhd16a	Abhydrolase domain containing 16A. (543 aa)
	H2MEE3_ORYLA	Carrier domain-containing protein. (524 aa)
	esd	S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (282 aa)
	hibch	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (381 aa)
	LOC101158556	Uncharacterized protein. (294 aa)
	LOC105357122	Uncharacterized protein. (409 aa)
	Abhd13	Abhydrolase domain containing 13. (348 aa)
	H2MXC6_ORYLA	Uncharacterized protein. (400 aa)
	ufsp1	UFM1-specific peptidase 1 (non-functional). (236 aa)
	ppt2	Palmitoyl-protein thioesterase 2. (305 aa)
	lypla1	Lysophospholipase 1. (241 aa)
	LOC110014434	Uncharacterized protein. (419 aa)
	LOC101175554	PNKD metallo-beta-lactamase domain containing. (360 aa)
	LOC101159289	Si:ch211-117n7.7. (355 aa)
	LOC101166202	ATP binding cassette subfamily D member 1. (750 aa)
	LOC101172604	Thioesterase superfamily member 4. (246 aa)
	LOC101157806	Uncharacterized protein. (294 aa)
	LOC101166298	Uncharacterized protein. (466 aa)
	olah	Oleoyl-ACP hydrolase. (255 aa)
	LOC101173294	Abhydrolase domain containing 17A. (330 aa)
	LOC101161510	Peptidase_S9 domain-containing protein. (354 aa)
	abhd10	Transgelin 3b. (290 aa)
	LOC101166391	Uncharacterized protein. (292 aa)
	HAGHL	Hydroxyacylglutathione hydrolase like. (282 aa)
	aamdc	Adipogenesis associated, Mth938 domain containing. (124 aa)
	LOC105358390	Uncharacterized protein. (410 aa)
	LOC101166497	Uncharacterized protein. (427 aa)
	H2LAP5_ORYLA	Bile_Hydr_Trans domain-containing protein. (230 aa)
	acaa2	Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
	acot9	Acyl-CoA thioesterase 9, tandem duplicate 2. (432 aa)
	abhd12	Abhydrolase domain containing 12. (375 aa)
	LOC101170716	Carrier domain-containing protein. (2203 aa)
	acot11	Acyl-coenzyme A thioesterase 11. (584 aa)
	abcd3	ATP-binding cassette, sub-family D (ALD), member 3a. (657 aa)
	acot7	Acyl-CoA thioesterase 7. (370 aa)
	lypla2	Lysophospholipase 2. (230 aa)
	LOC101159853	Uncharacterized protein. (613 aa)
	LOC101173669	ATP-binding cassette, sub-family D (ALD), member 2. (734 aa)
	abhd12b	Hydrolase_4 domain-containing protein. (327 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Abhd13	hibch	ENSORLP00000022497	ENSORLP00000018847	Abhydrolase domain containing 13.	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	0.496
Abhd13	lypla1	ENSORLP00000022497	ENSORLP00000031158	Abhydrolase domain containing 13.	Lysophospholipase 1.	0.580
Abhd13	lypla2	ENSORLP00000022497	ENSORLP00000009360	Abhydrolase domain containing 13.	Lysophospholipase 2.	0.580
H2LAP5_ORYLA	lypla1	ENSORLP00000002957	ENSORLP00000031158	Bile_Hydr_Trans domain-containing protein.	Lysophospholipase 1.	0.474
H2LAP5_ORYLA	lypla2	ENSORLP00000002957	ENSORLP00000009360	Bile_Hydr_Trans domain-containing protein.	Lysophospholipase 2.	0.474
H2MEE3_ORYLA	hibch	ENSORLP00000016949	ENSORLP00000018847	Carrier domain-containing protein.	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	0.414
H2MEE3_ORYLA	olah	ENSORLP00000016949	ENSORLP00000039303	Carrier domain-containing protein.	Oleoyl-ACP hydrolase.	0.514
H2MXC6_ORYLA	lypla1	ENSORLP00000023585	ENSORLP00000031158	Uncharacterized protein.	Lysophospholipase 1.	0.474
H2MXC6_ORYLA	lypla2	ENSORLP00000023585	ENSORLP00000009360	Uncharacterized protein.	Lysophospholipase 2.	0.474
HAGHL	esd	ENSORLP00000041763	ENSORLP00000017507	Hydroxyacylglutathione hydrolase like.	S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.	0.412
LOC101159289	LOC101161510	ENSORLP00000033715	ENSORLP00000039672	Si:ch211-117n7.7.	Peptidase_S9 domain-containing protein.	0.433
LOC101159289	LOC101173294	ENSORLP00000033715	ENSORLP00000039344	Si:ch211-117n7.7.	Abhydrolase domain containing 17A.	0.435
LOC101159289	abhd17b	ENSORLP00000033715	ENSORLP00000013545	Si:ch211-117n7.7.	Abhydrolase domain containing 17B.	0.401
LOC101159289	lypla1	ENSORLP00000033715	ENSORLP00000031158	Si:ch211-117n7.7.	Lysophospholipase 1.	0.507
LOC101159289	lypla2	ENSORLP00000033715	ENSORLP00000009360	Si:ch211-117n7.7.	Lysophospholipase 2.	0.507
LOC101159853	LOC101172604	ENSORLP00000009813	ENSORLP00000035053	Uncharacterized protein.	Thioesterase superfamily member 4.	0.559
LOC101159853	aamdc	ENSORLP00000009813	ENSORLP00000000798	Uncharacterized protein.	Adipogenesis associated, Mth938 domain containing.	0.507
LOC101159853	acot13	ENSORLP00000009813	ENSORLP00000016088	Uncharacterized protein.	Acyl-CoA thioesterase 13.	0.570
LOC101159853	acot7	ENSORLP00000009813	ENSORLP00000005378	Uncharacterized protein.	Acyl-CoA thioesterase 7.	0.497
LOC101159853	hibch	ENSORLP00000009813	ENSORLP00000018847	Uncharacterized protein.	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	0.461