(45 nodes) Ligase activity, forming carbon-nitrogen bonds network (Oryzias latipes)

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	fpgs	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (576 aa)
	nadsyn1	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (699 aa)
	cep41	Centrosomal protein 41. (394 aa)
	Ttll5	Uncharacterized protein. (185 aa)
	rimklb	Ribosomal modification protein rimK-like family member A. (423 aa)
	ASS1	Argininosuccinate synthase 1. (412 aa)
	Cad	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (987 aa)
	asns	Asparagine synthetase [glutamine-hydrolyzing]. (561 aa)
	gclc	Glutamate-cysteine ligase, catalytic subunit. (592 aa)
	LOC101161325	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (473 aa)
	gmps	Guanine monophosphate synthase. (691 aa)
	ttl	Tubulin tyrosine ligase. (409 aa)
	naprt	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (563 aa)
	gss	Glutathione synthetase. (476 aa)
	ttll9	Tubulin tyrosine ligase-like family, member 9. (440 aa)
	ttll7	Tubulin tyrosine ligase-like family, member 7. (944 aa)
	LOC101171914	Fleer. (653 aa)
	glul	Glutamine synthetase. (371 aa)
	ENSORLP00000040334	Uncharacterized protein. (273 aa)
	ttll6	Tubulin tyrosine ligase-like family, member 6. (783 aa)
	dph6	Diphthamine biosynthesis 6. (694 aa)
	ttll4	Tubulin tyrosine ligase-like family, member 4. (949 aa)
	LOC101163918	Glutamine synthetase. (368 aa)
	tpgs1	Uncharacterized protein. (331 aa)
	LOC101165095	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (589 aa)
	mthfd1l	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (966 aa)
	pfas	Phosphoribosylformylglycinamidine synthase. (1319 aa)
	asnsd1	Asparagine synthetase domain containing 1. (608 aa)
	LOC101171790	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (457 aa)
	LOC101174548	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b. (881 aa)
	qrsl1	Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the amidase family. GatA subfamily. (515 aa)
	gclm	Glutamate-cysteine ligase, modifier subunit. (272 aa)
	ttll1	Tubulin tyrosine ligase-like family, member 1. (424 aa)
	H2MLV1_ORYLA	Uncharacterized protein. (141 aa)
	cps1	Carbamoyl-phosphate synthase 1, mitochondrial. (1515 aa)
	paics	AIRC domain-containing protein. (999 aa)
	ttll11	Tubulin tyrosine ligase-like family, member 11. (718 aa)
	ppcs	Phosphopantothenoylcysteine synthetase. (321 aa)
	ghdc	GH3 domain containing. (630 aa)
	LOC101162945	Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (453 aa)
	hlcs	Holocarboxylase synthetase. (916 aa)
	gart	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1007 aa)
	gatc	Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatC family. (135 aa)
	gatb	Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily. (487 aa)
	LOC101156102	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (597 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASS1	Cad	ENSORLP00000034752	ENSORLP00000010928	Argininosuccinate synthase 1.	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	0.993
ASS1	LOC101156102	ENSORLP00000034752	ENSORLP00000010373	Argininosuccinate synthase 1.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.472
ASS1	LOC101161325	ENSORLP00000034752	ENSORLP00000013285	Argininosuccinate synthase 1.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.947
ASS1	LOC101162945	ENSORLP00000034752	ENSORLP00000006117	Argininosuccinate synthase 1.	Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.947
ASS1	LOC101163918	ENSORLP00000034752	ENSORLP00000017599	Argininosuccinate synthase 1.	Glutamine synthetase.	0.443
ASS1	LOC101165095	ENSORLP00000034752	ENSORLP00000017800	Argininosuccinate synthase 1.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.472
ASS1	LOC101171790	ENSORLP00000034752	ENSORLP00000021266	Argininosuccinate synthase 1.	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.947
ASS1	asns	ENSORLP00000034752	ENSORLP00000011076	Argininosuccinate synthase 1.	Asparagine synthetase [glutamine-hydrolyzing].	0.960
ASS1	asnsd1	ENSORLP00000034752	ENSORLP00000019140	Argininosuccinate synthase 1.	Asparagine synthetase domain containing 1.	0.492
ASS1	cps1	ENSORLP00000034752	ENSORLP00000020044	Argininosuccinate synthase 1.	Carbamoyl-phosphate synthase 1, mitochondrial.	0.986
ASS1	gart	ENSORLP00000034752	ENSORLP00000007887	Argininosuccinate synthase 1.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.724
ASS1	glul	ENSORLP00000034752	ENSORLP00000038634	Argininosuccinate synthase 1.	Glutamine synthetase.	0.443
ASS1	paics	ENSORLP00000034752	ENSORLP00000002464	Argininosuccinate synthase 1.	AIRC domain-containing protein.	0.628
Cad	ASS1	ENSORLP00000010928	ENSORLP00000034752	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	Argininosuccinate synthase 1.	0.993
Cad	LOC101156102	ENSORLP00000010928	ENSORLP00000010373	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.503
Cad	LOC101161325	ENSORLP00000010928	ENSORLP00000013285	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.944
Cad	LOC101162945	ENSORLP00000010928	ENSORLP00000006117	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.944
Cad	LOC101163918	ENSORLP00000010928	ENSORLP00000017599	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	Glutamine synthetase.	0.953
Cad	LOC101165095	ENSORLP00000010928	ENSORLP00000017800	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.503
Cad	LOC101171790	ENSORLP00000010928	ENSORLP00000021266	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.944