STRINGSTRING
tdo2 tdo2 flvcr1 flvcr1 ptges2 ptges2 COX1 COX1 suox suox stc2 stc2 LOC101157611 LOC101157611 ENSORLP00000027733 ENSORLP00000027733 ENSORLP00000027893 ENSORLP00000027893 LOC101160974 LOC101160974 LOC101163059 LOC101163059 sdhc sdhc mb mb nox5 nox5 LOC101174598 LOC101174598 LOC101158279 LOC101158279 ENSORLP00000031017 ENSORLP00000031017 gb-3 gb-3 LOC101163130 LOC101163130 LOC110015551 LOC110015551 ENSORLP00000032232 ENSORLP00000032232 LOC101174266 LOC101174266 LOC101175163 LOC101175163 adgb adgb gb-4 gb-4 LOC101170577 LOC101170577 LOC101154833 LOC101154833 LOC101174108 LOC101174108 slc48a1 slc48a1 ENSORLP00000040425 ENSORLP00000040425 LOC101164857 LOC101164857 ENSORLP00000041141 ENSORLP00000041141 cygb cygb ngb ngb cyp3a40 cyp3a40 LOC101157144 LOC101157144 LOC101156755 LOC101156755 ENSORLP00000043209 ENSORLP00000043209 LOC105356108 LOC105356108 LOC101158486 LOC101158486 nos1 nos1 LOC101165110 LOC101165110 cygb1 cygb1 LOC101158704 LOC101158704 fa2h fa2h LOC101169383 LOC101169383 LOC101167965 LOC101167965 LOC101165274 LOC101165274 LOC101165021 LOC101165021 gucy1a2 gucy1a2 cyp11b cyp11b sdhd sdhd LOC101175691 LOC101175691 ptgs2 ptgs2 LOC101171684 LOC101171684 LOC101168758 LOC101168758 steap4 steap4 LOC101162575 LOC101162575 LOC101174506 LOC101174506 LOC101160349 LOC101160349 LOC101155998 LOC101155998 rttn rttn LOC101173499 LOC101173499 cyp11a cyp11a LOC101157155 LOC101157155 LOC101167098 LOC101167098 LOC101164878 LOC101164878 LOC101165632 LOC101165632 LOC101170499 LOC101170499 H2LNR2_ORYLA H2LNR2_ORYLA hebp3 hebp3 LOC101169805 LOC101169805 cyp19b cyp19b abcb6 abcb6 LOC101155030 LOC101155030 LOC101159018 LOC101159018 duox1 duox1 LOC101175238 LOC101175238 HBE1 HBE1 LOC101158529 LOC101158529 gb-2 gb-2 LOC101175481 LOC101175481 gb gb LOC101174997 LOC101174997 LOC101161174 LOC101161174 LOC101157281 LOC101157281 LOC101173088 LOC101173088 LOC101158047 LOC101158047 LOC101157802 LOC101157802 LOC101155538 LOC101155538 LOC101155293 LOC101155293 LOC101174538 LOC101174538 cyp26b1 cyp26b1 H2LCY1_ORYLA H2LCY1_ORYLA LOC101170468 LOC101170468 LOC101174651 LOC101174651 LOC101161793 LOC101161793 cyp17a2 cyp17a2 LOC101163759 LOC101163759 cat cat LOC101159216 LOC101159216 LOC101160538 LOC101160538 PTGIS PTGIS LOC101173634 LOC101173634 LOC101165867 LOC101165867 H2MFE5_ORYLA H2MFE5_ORYLA H2MFG3_ORYLA H2MFG3_ORYLA pgrmc1 pgrmc1 LOC101164588 LOC101164588 H2MGL6_ORYLA H2MGL6_ORYLA LOC101165838 LOC101165838 cyp1a cyp1a cyp26a1 cyp26a1 LOC101156051 LOC101156051 hebp1 hebp1 LOC101156566 LOC101156566 LOC101156965 LOC101156965 LOC101157528 LOC101157528 LOC105353996 LOC105353996 cyp2p3 cyp2p3 LOC101157767 LOC101157767 LOC101163641 LOC101163641 H2MJZ4_ORYLA H2MJZ4_ORYLA LOC101172325 LOC101172325 LOC101174341 LOC101174341 LOC101157991 LOC101157991 LOC101155397 LOC101155397 tbxas1 tbxas1 LOC101165473 LOC101165473 thap4 thap4 flvcr2 flvcr2 LOC101155419 LOC101155419 H2MR15_ORYLA H2MR15_ORYLA LOC101172860 LOC101172860 H2MT51_ORYLA H2MT51_ORYLA TPO TPO LOC101157008 LOC101157008 pxdn pxdn LOC101173184 LOC101173184 pgrmc2 pgrmc2 H2MVC7_ORYLA H2MVC7_ORYLA LOC101171965 LOC101171965 cyp17 cyp17 fabp2 fabp2 cyp3a cyp3a LOC101169416 LOC101169416 H2N0C8_ORYLA H2N0C8_ORYLA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
tdo2Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (468 aa)
flvcr1Feline leukemia virus subgroup C cellular receptor 1. (551 aa)
ptges2Prostaglandin E synthase 2-like. (412 aa)
COX1Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (518 aa)
suoxSulfite oxidase. (568 aa)
stc2Stanniocalcin 2. (284 aa)
LOC101157611Cytochrome b561 family, member D1. (233 aa)
ENSORLP00000027733Uncharacterized protein. (182 aa)
ENSORLP00000027893Uncharacterized protein. (132 aa)
LOC101160974Cytochrome P450, family 2, subfamily N, polypeptide 13; Belongs to the cytochrome P450 family. (518 aa)
LOC101163059Uncharacterized protein. (192 aa)
sdhcSuccinate dehydrogenase complex, subunit C, integral membrane protein. (188 aa)
mbMyoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. (147 aa)
nox5NADPH oxidase, EF-hand calcium binding domain 5. (807 aa)
LOC101174598C1q domain-containing protein. (875 aa)
LOC101158279Hemoglobin, beta adult 1; Belongs to the globin family. (165 aa)
ENSORLP00000031017Si:ch211-5k11.8; Belongs to the globin family. (145 aa)
gb-3GLOBIN domain-containing protein; Belongs to the globin family. (177 aa)
LOC101163130Heme binding protein 2. (192 aa)
LOC110015551C1q domain-containing protein. (875 aa)
ENSORLP00000032232Uncharacterized protein. (178 aa)
LOC101174266Uncharacterized protein; Belongs to the cytochrome P450 family. (500 aa)
LOC101175163Heme oxygenase 2b. (307 aa)
adgbAndroglobin. (1038 aa)
gb-4GLOBIN domain-containing protein; Belongs to the globin family. (219 aa)
LOC101170577Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (186 aa)
LOC101154833Uncharacterized protein. (192 aa)
LOC101174108C1q domain-containing protein. (875 aa)
slc48a1Solute carrier family 48 member 1a. (144 aa)
ENSORLP00000040425Myeloid-specific peroxidase. (414 aa)
LOC101164857Heme-binding protein soul3. (277 aa)
ENSORLP00000041141Uncharacterized protein. (119 aa)
cygbCytoglobin-2; May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer. Belongs to the globin family. (194 aa)
ngbNeuroglobin; Belongs to the globin family. (185 aa)
cyp3a40Cytochrome P450 3A40. (502 aa)
LOC101157144Uncharacterized protein; Belongs to the cytochrome P450 family. (491 aa)
LOC101156755Uncharacterized protein; Belongs to the cytochrome P450 family. (491 aa)
ENSORLP00000043209Alpha-1-microglobulin/bikunin precursor. (355 aa)
LOC105356108Uncharacterized protein. (388 aa)
LOC101158486Cytochrome b5 type A (microsomal); Belongs to the cytochrome b5 family. (142 aa)
nos1Uncharacterized protein. (1438 aa)
LOC101165110Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
cygb1Cytoglobin-1; May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer. Belongs to the globin family. (177 aa)
LOC101158704Cytochrome P450, family 1, subfamily D, polypeptide 1; Belongs to the cytochrome P450 family. (543 aa)
fa2hFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (381 aa)
LOC101169383Cytochrome b5 domain containing 2; Belongs to the cytochrome b5 family. (253 aa)
LOC101167965Indoleamine 2,3-dioxygenase 1. (420 aa)
LOC101165274Uncharacterized protein. (507 aa)
LOC101165021Uncharacterized protein. (507 aa)
gucy1a2Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (806 aa)
cyp11bCytochrome P450 11beta; Belongs to the cytochrome P450 family. (541 aa)
sdhdSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (158 aa)
LOC101175691Si:dkey-91i10.3; Belongs to the cytochrome P450 family. (527 aa)
ptgs2EGF-like domain-containing protein. (607 aa)
LOC101171684Myeloid-specific peroxidase. (814 aa)
LOC101168758MFS domain-containing protein. (532 aa)
steap4STEAP family member 4. (472 aa)
LOC101162575Cytochrome P450, family 4, subfamily V, polypeptide 8; Belongs to the cytochrome P450 family. (516 aa)
LOC101174506Uncharacterized protein; Belongs to the cytochrome P450 family. (502 aa)
LOC101160349Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (512 aa)
LOC101155998Cytochrome b5 type B; Belongs to the cytochrome b5 family. (151 aa)
rttnRotatin. (2121 aa)
LOC101173499Cytochrome P450, family 7, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (491 aa)
cyp11aCholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (517 aa)
LOC101157155Cytochrome P450, family 21, subfamily A, polypeptide 2; Belongs to the cytochrome P450 family. (519 aa)
LOC101167098Cytochrome P450, family 2, subfamily U, polypeptide 1; Belongs to the cytochrome P450 family. (564 aa)
LOC101164878Cytochrome P450, family 2, subfamily R, polypeptide 1; Belongs to the cytochrome P450 family. (512 aa)
LOC101165632Cytochrome P450, family 24, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (513 aa)
LOC101170499Cytochrome P450, family 4, subfamily F, polypeptide 3; Belongs to the cytochrome P450 family. (529 aa)
H2LNR2_ORYLAEosinophil peroxidase. (397 aa)
hebp3Heme-binding protein 3. (213 aa)
LOC101169805Uncharacterized protein. (418 aa)
cyp19bAromatase B; Belongs to the cytochrome P450 family. (499 aa)
abcb6ATP-binding cassette, sub-family B (MDR/TAP), member 6a. (850 aa)
LOC101155030Hemoglobin embryonic subunit alpha-like. (144 aa)
LOC101159018GLOBIN domain-containing protein; Belongs to the globin family. (145 aa)
duox1Dual oxidase. (1477 aa)
LOC101175238GLOBIN domain-containing protein; Belongs to the globin family. (150 aa)
HBE1Hemoglobin subunit epsilon 1; Belongs to the globin family. (147 aa)
LOC101158529Beta-type globin; Belongs to the globin family. (147 aa)
gb-2Embryonic beta-type globin; Belongs to the globin family. (147 aa)
LOC101175481Alpha-type globin; Belongs to the globin family. (143 aa)
gbHemoglobin embryonic subunit alpha; Involved in oxygen transport from gills to the various peripheral tissues. (144 aa)
LOC101174997GLOBIN domain-containing protein; Belongs to the globin family. (144 aa)
LOC101161174Prostaglandin-endoperoxide synthase 1. (597 aa)
LOC101157281Cytochrome P450, family 27, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (542 aa)
LOC101173088Cytochrome b5 reductase 4. (516 aa)
LOC101158047Uncharacterized protein; Belongs to the cytochrome P450 family. (492 aa)
LOC101157802Uncharacterized protein; Belongs to the cytochrome P450 family. (512 aa)
LOC101155538Uncharacterized protein; Belongs to the cytochrome P450 family. (498 aa)
LOC101155293Uncharacterized protein; Belongs to the cytochrome P450 family. (497 aa)
LOC101174538Eukaryotic translation initiation factor 2-alpha kinase 1. (656 aa)
cyp26b1Cytochrome P450 26B1; Belongs to the cytochrome P450 family. (512 aa)
H2LCY1_ORYLAUncharacterized protein. (123 aa)
LOC101170468Zgc:163057; Belongs to the globin family. (141 aa)
LOC101174651Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens. (518 aa)
LOC101161793Cytochrome b561 family, member D2. (224 aa)
cyp17a2Cytochrome P450 family 17 polypeptide 2; Belongs to the cytochrome P450 family. (521 aa)
LOC101163759Cytochrome P450, family 26, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (525 aa)
catCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
LOC101159216Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (527 aa)
LOC101160538Si:ch211-113j14.1; Belongs to the cytochrome P450 family. (526 aa)
PTGISProstaglandin I2 synthase; Belongs to the cytochrome P450 family. (512 aa)
LOC101173634Prostaglandin-endoperoxide synthase 1. (589 aa)
LOC101165867Cytochrome P450, family 20, subfamily A, polypeptide 1. (463 aa)
H2MFE5_ORYLAUncharacterized protein; Belongs to the cytochrome P450 family. (488 aa)
H2MFG3_ORYLAUncharacterized protein; Belongs to the cytochrome P450 family. (488 aa)
pgrmc1Progestin receptor membrane component 1; Belongs to the cytochrome b5 family. (181 aa)
LOC101164588Si:ch211-79k12.1. (303 aa)
H2MGL6_ORYLAUncharacterized protein. (182 aa)
LOC101165838Cytochrome P450, family 4, subfamily T, polypeptide 8; Belongs to the cytochrome P450 family. (515 aa)
cyp1aCytochrome P450 1A1; Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (521 aa)
cyp26a1Cytochrome P450 26A1; Belongs to the cytochrome P450 family. (488 aa)
LOC101156051Cytochrome P450, family 27, subfamily A, polypeptide 7; Belongs to the cytochrome P450 family. (516 aa)
hebp1Uncharacterized protein. (191 aa)
LOC101156566Cytochrome P450, family 2, subfamily N, polypeptide 13; Belongs to the cytochrome P450 family. (497 aa)
LOC101156965Cytochrome P450, family 2, subfamily N, polypeptide 13; Belongs to the cytochrome P450 family. (497 aa)
LOC101157528Cytochrome P450, family 2, subfamily AD, polypeptide 2; Belongs to the cytochrome P450 family. (493 aa)
LOC105353996Uncharacterized protein; Belongs to the cytochrome P450 family. (498 aa)
cyp2p3Cytochrome P450 2P3; Belongs to the cytochrome P450 family. (498 aa)
LOC101157767Uncharacterized protein; Belongs to the cytochrome P450 family. (498 aa)
LOC101163641Heme oxygenase 2a. (332 aa)
H2MJZ4_ORYLADGCR8 microprocessor complex subunit. (769 aa)
LOC101172325Cytochrome P450, family 27, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (522 aa)
LOC101174341Nuclear receptor subfamily 1, group D, member 4b. (568 aa)
LOC101157991Uncharacterized protein; Belongs to the cytochrome P450 family. (504 aa)
LOC101155397Uncharacterized protein; Belongs to the cytochrome P450 family. (501 aa)
tbxas1Thromboxane A synthase 1 (platelet); Belongs to the cytochrome P450 family. (555 aa)
LOC101165473Solute carrier family 48 member 1b. (164 aa)
thap4THAP domain containing 4. (171 aa)
flvcr2Feline leukemia virus subgroup C cellular receptor family member 2. (470 aa)
LOC101155419Uncharacterized protein; Belongs to the cytochrome P450 family. (526 aa)
H2MR15_ORYLACytochrome P450, family 1, subfamily C, polypeptide 2; Belongs to the cytochrome P450 family. (514 aa)
LOC101172860X globin; Belongs to the globin family. (198 aa)
H2MT51_ORYLAUncharacterized protein. (309 aa)
TPOThyroid peroxidase. (826 aa)
LOC101157008Cytochrome P450, family 8, subfamily B, polypeptide 2; Belongs to the cytochrome P450 family. (511 aa)
pxdnPeroxidasin. (1481 aa)
LOC101173184BTB domain containing 6. (497 aa)
pgrmc2Progestin receptor membrane component 2; Belongs to the cytochrome b5 family. (198 aa)
H2MVC7_ORYLABTB (POZ) domain containing 6b. (982 aa)
LOC101171965Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
cyp17Steroid 17-alpha-hydroxylase/17,20 lyase; Conversion of pregnenolone and progesterone to their 17- alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction; Belongs to the cytochrome P450 family. (595 aa)
fabp2Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (570 aa)
cyp3aUncharacterized protein. (500 aa)
LOC101169416Uncharacterized protein; Belongs to the cytochrome P450 family. (489 aa)
H2N0C8_ORYLACytochrome P450, family 51; Belongs to the cytochrome P450 family. (200 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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