(79 nodes) Growth cone network (Oryzias latipes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	frmd7	FERM domain-containing protein. (764 aa)
	H2L2U9_ORYLA	SH3 and multiple ankyrin repeat domains 2a. (1494 aa)
	LOC101165461	Myosin IXAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2214 aa)
	H2L8C2_ORYLA	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1125 aa)
	LOC101170271	Nerve growth factor receptor a (TNFR superfamily, member 16). (389 aa)
	copa	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1219 aa)
	abitram	Actin binding transcription modulator. (181 aa)
	ELAVL2	ELAV-like protein; Belongs to the RRM elav family. (411 aa)
	LOC101165094	Cordon-bleu WH2 repeat protein. (1444 aa)
	LOC101157960	Unc-5 netrin receptor C. (937 aa)
	LOC101163354	Stathmin; Belongs to the stathmin family. (180 aa)
	fmr1	Fragile X mental retardation 1. (598 aa)
	LOC101161903	Cyclin-dependent kinase 5 activator. (328 aa)
	LOC101170217	Abl-interactor 1b. (496 aa)
	LAMP5	Lysosomal associated membrane protein family member 5. (274 aa)
	LOC101156969	Uncharacterized protein. (281 aa)
	H2M7G4_ORYLA	Si:dkey-280e21.3. (335 aa)
	zfyve27	Zinc finger, FYVE domain containing 27. (419 aa)
	LOC101154983	Fragile X mental retardation, autosomal homolog 2. (674 aa)
	fxr1	Fragile X mental retardation, autosomal homolog 1. (679 aa)
	cdk5r1	Cyclin-dependent kinase 5 activator. (302 aa)
	disc1	DISC1 scaffold protein. (814 aa)
	stmn2	Stathmin; Belongs to the stathmin family. (180 aa)
	tsc1	TSC complex subunit 1b. (1198 aa)
	exoc4	Exocyst complex component 4. (983 aa)
	syap1	Synapse associated protein 1. (361 aa)
	H2MMP5_ORYLA	Microtubule-associated protein. (285 aa)
	pink1	PTEN induced kinase 1. (577 aa)
	kif21b	Kinesin family member 21B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1694 aa)
	LOC101164149	Teashirt zinc finger homeobox 3a. (1106 aa)
	CDKL5	Cyclin dependent kinase like 5. (996 aa)
	elavl4	ELAV-like protein; Belongs to the RRM elav family. (442 aa)
	Zpr1	ZPR1 zinc finger. (454 aa)
	LOC101164549	ATCAY kinesin light chain interacting caytaxin a. (369 aa)
	cdk5	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	exoc8	Exocyst complex component 8. (688 aa)
	c9orf72	Zgc:100846. (460 aa)
	LOC101156094	Whirlin b. (773 aa)
	LOC101169237	ATCAY kinesin light chain interacting caytaxin b. (305 aa)
	fez1	Fasciculation and elongation protein zeta 1 (zygin I). (405 aa)
	LOC101174571	Cyclin-dependent kinase 5 activator. (334 aa)
	LOC101165934	Dihydropyrimidinase like 3. (653 aa)
	rufy3	RUN and FYVE domain containing 3. (673 aa)
	lrrk2	Leucine-rich repeat kinase 2. (2241 aa)
	LOC101164215	Uncharacterized protein. (1289 aa)
	psen2	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (421 aa)
	LOC101159571	Cyclin-dependent kinase 5, regulatory subunit 2b (p39). (288 aa)
	LOC101155741	Uncharacterized protein. (278 aa)
	l1cam	L1 cell adhesion molecule, paralog a. (1275 aa)
	tshz3	Teashirt zinc finger homeobox 3b. (1214 aa)
	LOC101165870	Microtubule-associated protein. (539 aa)
	ENSORLP00000027113	RNAse_Pc domain-containing protein; Belongs to the pancreatic ribonuclease family. (139 aa)
	dcc	DCC netrin 1 receptor. (1501 aa)
	LOC101174433	Unc-5 netrin receptor C. (955 aa)
	LOC105355926	C2H2-type domain-containing protein. (1423 aa)
	LOC101160131	Uncharacterized protein. (325 aa)
	ENSORLP00000031311	Uncharacterized protein. (248 aa)
	flrt3	Fibronectin leucine rich transmembrane 3. (650 aa)
	ENSORLP00000035838	FERM_f0 domain-containing protein. (122 aa)
	gap43	Growth associated protein 43. (242 aa)
	dtnbp1	Dystrobrevin binding protein 1b. (259 aa)
	LOC101160113	Microtubule-associated protein. (536 aa)
	LOC101174816	Cyclin-dependent kinase-like 5. (1153 aa)
	ABI1	Abl-interactor 1a. (641 aa)
	rtn4r	Reticulon 4 receptor. (488 aa)
	LOC101166088	Nerve growth factor receptor b. (434 aa)
	ENSORLP00000039489	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (198 aa)
	fkbp15	Peptidylprolyl isomerase. (1176 aa)
	lrrtm1	Leucine rich repeat transmembrane neuronal 1. (525 aa)
	exoc7	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (710 aa)
	LOC101157175	Uncharacterized protein. (336 aa)
	whrn	Whirlin a. (966 aa)
	cib1	Calcium and integrin binding 1 (calmyrin). (189 aa)
	LOC101160327	Cytoplasmic polyadenylation element binding protein 4a. (741 aa)
	shtn1	Shootin 1. (491 aa)
	neo1	Neogenin 1b. (1455 aa)
	auts2	Activator of transcription and developmental regulator AUTS2 a. (1282 aa)
	LOC101154844	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (410 aa)
	LOC101173373	Glycoprotein M6Aa. (278 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABI1	LOC101170217	ENSORLP00000037107	ENSORLP00000011940	Abl-interactor 1a.	Abl-interactor 1b.	0.901
CDKL5	fmr1	ENSORLP00000020490	ENSORLP00000011409	Cyclin dependent kinase like 5.	Fragile X mental retardation 1.	0.447
ENSORLP00000031311	pink1	ENSORLP00000031311	ENSORLP00000020035	Uncharacterized protein.	PTEN induced kinase 1.	0.549
ENSORLP00000031311	tsc1	ENSORLP00000031311	ENSORLP00000018027	Uncharacterized protein.	TSC complex subunit 1b.	0.545
ENSORLP00000035838	H2L2U9_ORYLA	ENSORLP00000035838	ENSORLP00000000049	FERM_f0 domain-containing protein.	SH3 and multiple ankyrin repeat domains 2a.	0.902
ENSORLP00000039489	H2L8C2_ORYLA	ENSORLP00000039489	ENSORLP00000002093	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.947
H2L2U9_ORYLA	ENSORLP00000035838	ENSORLP00000000049	ENSORLP00000035838	SH3 and multiple ankyrin repeat domains 2a.	FERM_f0 domain-containing protein.	0.902
H2L8C2_ORYLA	ENSORLP00000039489	ENSORLP00000002093	ENSORLP00000039489	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.947
H2M7G4_ORYLA	LOC101164215	ENSORLP00000014419	ENSORLP00000024796	Si:dkey-280e21.3.	Uncharacterized protein.	0.475
H2M7G4_ORYLA	l1cam	ENSORLP00000014419	ENSORLP00000025913	Si:dkey-280e21.3.	L1 cell adhesion molecule, paralog a.	0.475
H2M7G4_ORYLA	rufy3	ENSORLP00000014419	ENSORLP00000024752	Si:dkey-280e21.3.	RUN and FYVE domain containing 3.	0.628
H2MMP5_ORYLA	cdk5	ENSORLP00000019991	ENSORLP00000021947	Microtubule-associated protein.	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.	0.717
H2MMP5_ORYLA	gap43	ENSORLP00000019991	ENSORLP00000036090	Microtubule-associated protein.	Growth associated protein 43.	0.442
LOC101154844	LOC101170271	ENSORLP00000044855	ENSORLP00000003150	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Nerve growth factor receptor a (TNFR superfamily, member 16).	0.419
LOC101154844	cdk5	ENSORLP00000044855	ENSORLP00000021947	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.	0.487
LOC101154844	pink1	ENSORLP00000044855	ENSORLP00000020035	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	PTEN induced kinase 1.	0.527
LOC101154844	psen2	ENSORLP00000044855	ENSORLP00000025023	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.449
LOC101154983	fmr1	ENSORLP00000014502	ENSORLP00000011409	Fragile X mental retardation, autosomal homolog 2.	Fragile X mental retardation 1.	0.964
LOC101154983	fxr1	ENSORLP00000014502	ENSORLP00000014777	Fragile X mental retardation, autosomal homolog 2.	Fragile X mental retardation, autosomal homolog 1.	0.912
LOC101156094	whrn	ENSORLP00000022185	ENSORLP00000041625	Whirlin b.	Whirlin a.	0.554