(112 nodes) Synaptic vesicle membrane network (Oryzias latipes)

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Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	UNC13A	Unc-13 homolog A. (1876 aa)
	LOC101172966	Syntaxin 6; Belongs to the syntaxin family. (249 aa)
	borcs5	BLOC-1 related complex subunit 5. (198 aa)
	H2L667_ORYLA	Uncharacterized protein. (317 aa)
	LOC101155198	Si:dkey-16l2.16. (210 aa)
	syt12	Synaptotagmin XII. (429 aa)
	slc18a2	Solute carrier family 18 member 2. (480 aa)
	LOC101173142	Synaptic vesicle glycoprotein 2. (427 aa)
	LOC101168222	Proline-rich transmembrane protein 1. (241 aa)
	scamp1	Secretory carrier-associated membrane protein. (337 aa)
	SYNDIG1	Synapse differentiation inducing 1. (267 aa)
	DNM1L	Dynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (721 aa)
	LOC101171191	Uncharacterized protein. (344 aa)
	LOC101164150	Aa_trans domain-containing protein. (522 aa)
	tmem163	Transmembrane protein 163. (280 aa)
	unc13a	Uncharacterized protein. (1484 aa)
	LOC101165386	Solute carrier family 32 member 1. (526 aa)
	slc17a6	Solute carrier family 17 member 6. (581 aa)
	LOC101158606	Synaptophysin-like 2b. (248 aa)
	H2LNM4_ORYLA	Si:ch73-343g19.4. (101 aa)
	SLC17A6	Solute carrier family 17 member 6b. (581 aa)
	LOC101156534	Synaptotagmin Vb. (447 aa)
	svop	SV2 related protein a. (540 aa)
	ATP6V0C	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (153 aa)
	LOC101171415	Synaptogyrin. (222 aa)
	LOC101167994	MFS domain-containing protein. (577 aa)
	SYNPR	Synaptoporin. (144 aa)
	LOC101161399	Multiple C2 domains, transmembrane 2a. (1033 aa)
	LOC101164956	Synaptogyrin. (237 aa)
	LOC101162836	Synaptotagmin Ib. (407 aa)
	LOC101157543	Synaptic vesicle glycoprotein 2Ca. (734 aa)
	LOC101158539	Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (455 aa)
	LAMP5	Lysosomal associated membrane protein family member 5. (274 aa)
	LOC101158102	Synaptophysin-like 2a. (233 aa)
	syngr1	Synaptogyrin 1a. (254 aa)
	LOC101169210	Si:dkey-32e23.4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (692 aa)
	LOC101165727	Solute carrier family 17 member 8. (580 aa)
	LOC101175655	Solute carrier family 17 member 7a. (586 aa)
	LOC101174347	Synapsin IIa. (467 aa)
	atp6ap2	ATPase H+ transporting accessory protein 2. (374 aa)
	LOC101159507	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (154 aa)
	LOC101160735	Uncharacterized protein. (229 aa)
	LOC101171486	Synaptotagmin IXb. (527 aa)
	LOC101157351	Synaptogyrin. (238 aa)
	LOC101173249	Zgc:92912. (121 aa)
	gad2	Glutamate decarboxylase 2. (586 aa)
	UNC13C	Unc-13 homolog C. (1122 aa)
	syngr3	Synaptogyrin. (230 aa)
	LOC101163826	Synapsin I. (631 aa)
	LOC101167334	Synaptophysin-like 1. (239 aa)
	LOC101155482	Otoferlin a. (1957 aa)
	LOC101168118	MARVEL domain-containing protein. (293 aa)
	LOC101159986	Synaptic vesicle glycoprotein 2Bb. (688 aa)
	LOC101162590	Synaptic vesicle glycoprotein 2Ba. (661 aa)
	LOC101165235	ATPase H+ transporting accessory protein 1b. (446 aa)
	LOC101164923	Synaptic vesicle glycoprotein 2A. (737 aa)
	renbp	Renin binding protein. (421 aa)
	H2MVI7_ORYLA	C2 domain-containing protein. (529 aa)
	atp6v1f	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa)
	LOC101159330	Unc-13 homolog Ba (C. elegans). (1200 aa)
	lrrk2	Leucine-rich repeat kinase 2. (2241 aa)
	stx10	Syntaxin 10. (247 aa)
	atp6ap1	ATPase H+ transporting accessory protein 1a. (482 aa)
	clta	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (226 aa)
	LOC101167855	Synaptoporin. (281 aa)
	LOC101157206	Uncharacterized protein. (430 aa)
	LOC101161175	SV2 related protein b. (549 aa)
	LOC101167118	Uncharacterized protein. (4117 aa)
	LOC101164413	Vesicle-associated membrane protein 1. (152 aa)
	ATP6V1B2	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (492 aa)
	SCAMP1	Secretory carrier-associated membrane protein. (347 aa)
	c6h16orf70	Si:dkey-102f14.5. (416 aa)
	syt1	Synaptotagmin Ia. (536 aa)
	LOC101167425	Wolfram syndrome 1a (wolframin). (1041 aa)
	RAB26	RAB26, member RAS oncogene family. (253 aa)
	LOC101158431	Secretory carrier-associated membrane protein. (195 aa)
	LOC101169372	MFS domain-containing protein. (737 aa)
	LOC101166118	Synaptotagmin VIIb. (671 aa)
	ENSORLP00000031025	Proline-rich transmembrane protein 2. (170 aa)
	LOC101171075	Secretory carrier-associated membrane protein. (230 aa)
	ENSORLP00000031713	Uncharacterized protein. (168 aa)
	LOC101172219	Uncharacterized protein. (164 aa)
	LOC101167694	Complexin 3b. (157 aa)
	TMEM163	Transmembrane protein 163a. (292 aa)
	snapin	SNAP associated protein. (133 aa)
	LOC101169108	Synaptotagmin VIIa. (742 aa)
	atp6v1ba	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (503 aa)
	ENSORLP00000035319	Aa_trans domain-containing protein. (425 aa)
	dtnbp1	Dystrobrevin binding protein 1b. (259 aa)
	wfs1	Wolfram syndrome 1b (wolframin). (960 aa)
	syn2	Uncharacterized protein. (813 aa)
	mctp1	Multiple C2 domains, transmembrane 1a. (924 aa)
	LOC101160211	Synaptophysin a. (289 aa)
	LOC101165300	Uncharacterized protein. (217 aa)
	SLC18A1	Solute carrier family 18 member A1. (541 aa)
	LOC101165044	Multiple C2 domains, transmembrane 2b. (873 aa)
	LOC101161357	Uncharacterized protein. (528 aa)
	LOC101156568	Bassoon (presynaptic cytomatrix protein) b. (3697 aa)
	SV2C	Synaptic vesicle glycoprotein 2C. (736 aa)
	LOC101159503	BH4_2 domain-containing protein. (230 aa)
	LOC101161806	Synaptotagmin IIa. (432 aa)
	UNC13B	Unc-13 homolog B. (1474 aa)
	LOC101159330-2	Uncharacterized protein. (293 aa)
	cltb	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (228 aa)
	LOC101168415	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (779 aa)
	UNC13C-2	Uncharacterized protein. (1427 aa)
	LOC101160130	Otoferlin b. (1629 aa)
	vamp2	Vesicle-associated membrane protein 2. (154 aa)
	LOC101174010	Synaptotagmin IXa. (562 aa)
	stx16	Syntaxin 16; Belongs to the syntaxin family. (302 aa)
	rab35	RAB35, member RAS oncogene family b. (201 aa)
	ENSORLP00000045963	Uncharacterized protein. (72 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP6V0C	ATP6V1B2	ENSORLP00000009034	ENSORLP00000027466	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.981
ATP6V0C	LOC101159507	ENSORLP00000009034	ENSORLP00000014921	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.900
ATP6V0C	LOC101165235	ENSORLP00000009034	ENSORLP00000020349	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	ATPase H+ transporting accessory protein 1b.	0.976
ATP6V0C	atp6ap1	ENSORLP00000009034	ENSORLP00000025007	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	ATPase H+ transporting accessory protein 1a.	0.973
ATP6V0C	atp6ap2	ENSORLP00000009034	ENSORLP00000014646	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	ATPase H+ transporting accessory protein 2.	0.938
ATP6V0C	atp6v1ba	ENSORLP00000009034	ENSORLP00000034915	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.992
ATP6V0C	atp6v1f	ENSORLP00000009034	ENSORLP00000023241	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.994
ATP6V1B2	ATP6V0C	ENSORLP00000027466	ENSORLP00000009034	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.981
ATP6V1B2	LOC101159507	ENSORLP00000027466	ENSORLP00000014921	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.981
ATP6V1B2	LOC101165235	ENSORLP00000027466	ENSORLP00000020349	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	ATPase H+ transporting accessory protein 1b.	0.976
ATP6V1B2	atp6ap1	ENSORLP00000027466	ENSORLP00000025007	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	ATPase H+ transporting accessory protein 1a.	0.976
ATP6V1B2	atp6ap2	ENSORLP00000027466	ENSORLP00000014646	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	ATPase H+ transporting accessory protein 2.	0.936
ATP6V1B2	atp6v1ba	ENSORLP00000027466	ENSORLP00000034915	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.900
ATP6V1B2	atp6v1f	ENSORLP00000027466	ENSORLP00000023241	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.997
DNM1L	LOC101164413	ENSORLP00000004521	ENSORLP00000026958	Dynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Vesicle-associated membrane protein 1.	0.444
DNM1L	LOC101168415	ENSORLP00000004521	ENSORLP00000041842	Dynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.901
DNM1L	LOC101169210	ENSORLP00000004521	ENSORLP00000013948	Dynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Si:dkey-32e23.4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.901
DNM1L	LOC101173249	ENSORLP00000004521	ENSORLP00000015396	Dynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Zgc:92912.	0.444
DNM1L	clta	ENSORLP00000004521	ENSORLP00000025777	Dynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.508
DNM1L	cltb	ENSORLP00000004521	ENSORLP00000041564	Dynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.508