(36 nodes) Positive regulation of TOR signaling network (Oryzias latipes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GPR137B	G protein-coupled receptor 137B. (377 aa)
	lamtor1	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (160 aa)
	lamtor2	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (190 aa)
	wdr59	WD repeat domain 59. (986 aa)
	ENSORLP00000034659	Reelin domain-containing protein. (259 aa)
	lars1	Leucyl-tRNA synthetase b; Belongs to the class-I aminoacyl-tRNA synthetase family. (1184 aa)
	rptor	Regulatory associated protein of MTOR, complex 1. (1372 aa)
	ENSORLP00000029099	Uncharacterized protein. (282 aa)
	LOC101169236	WW domain-containing protein. (544 aa)
	htr6	5-hydroxytryptamine (serotonin) receptor 6; Belongs to the G-protein coupled receptor 1 family. (455 aa)
	clec16a	C-type lectin domain containing 16A. (1094 aa)
	sec13	SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (320 aa)
	lamtor4	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (101 aa)
	lamtor3	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (132 aa)
	golph3	Uncharacterized protein. (323 aa)
	mios	Missing oocyte, meiosis regulator, homolog (Drosophila). (880 aa)
	slc38a9	Solute carrier family 38 member 9. (551 aa)
	rragc	Ras-related GTP binding Ca. (392 aa)
	klhl22	Kelch-like family member 22. (621 aa)
	rictor	RPTOR independent companion of MTOR, complex 2 a. (1679 aa)
	flcn	Folliculin. (558 aa)
	H2M111_ORYLA	Uncharacterized protein. (723 aa)
	LOC101159757	G protein-coupled receptor 137. (387 aa)
	LOC101162152	Ras-related GTP binding A. (315 aa)
	wdr24	WD repeat domain 24. (788 aa)
	lamtor5	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (91 aa)
	gas6	Growth arrest-specific 6. (684 aa)
	H2LIM0_ORYLA	Uncharacterized protein. (726 aa)
	LOC101166973	Golgi phosphoprotein 3. (293 aa)
	wac	WW domain containing adaptor with coiled-coil a. (544 aa)
	gpr137c	G protein-coupled receptor 137c. (451 aa)
	seh1l	SEH1-like (S. cerevisiae); Belongs to the WD repeat SEC13 family. (341 aa)
	ctns	Cystinosin, lysosomal cystine transporter. (498 aa)
	LOC101171801	G protein-coupled receptor 137Bb. (396 aa)
	fnip1	Folliculin interacting protein 1. (1246 aa)
	lepa	Leptin-A; May function as part of a signaling pathway that acts to regulate the size of the body fat depot. (185 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSORLP00000029099	ENSORLP00000034659	ENSORLP00000029099	ENSORLP00000034659	Uncharacterized protein.	Reelin domain-containing protein.	0.944
ENSORLP00000034659	ENSORLP00000029099	ENSORLP00000034659	ENSORLP00000029099	Reelin domain-containing protein.	Uncharacterized protein.	0.944
ENSORLP00000034659	H2LIM0_ORYLA	ENSORLP00000034659	ENSORLP00000005849	Reelin domain-containing protein.	Uncharacterized protein.	0.944
H2LIM0_ORYLA	ENSORLP00000034659	ENSORLP00000005849	ENSORLP00000034659	Uncharacterized protein.	Reelin domain-containing protein.	0.944
H2M111_ORYLA	LOC101162152	ENSORLP00000012090	ENSORLP00000011636	Uncharacterized protein.	Ras-related GTP binding A.	0.997
H2M111_ORYLA	flcn	ENSORLP00000012090	ENSORLP00000014181	Uncharacterized protein.	Folliculin.	0.992
H2M111_ORYLA	fnip1	ENSORLP00000012090	ENSORLP00000044929	Uncharacterized protein.	Folliculin interacting protein 1.	0.949
H2M111_ORYLA	lamtor1	ENSORLP00000012090	ENSORLP00000042166	Uncharacterized protein.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1.	0.993
H2M111_ORYLA	lamtor2	ENSORLP00000012090	ENSORLP00000041020	Uncharacterized protein.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2.	0.950
H2M111_ORYLA	lamtor3	ENSORLP00000012090	ENSORLP00000022638	Uncharacterized protein.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3.	0.992
H2M111_ORYLA	lamtor4	ENSORLP00000012090	ENSORLP00000024027	Uncharacterized protein.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4.	0.992
H2M111_ORYLA	lamtor5	ENSORLP00000012090	ENSORLP00000007862	Uncharacterized protein.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5.	0.994
H2M111_ORYLA	lars1	ENSORLP00000012090	ENSORLP00000031889	Uncharacterized protein.	Leucyl-tRNA synthetase b; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.513
H2M111_ORYLA	mios	ENSORLP00000012090	ENSORLP00000020716	Uncharacterized protein.	Missing oocyte, meiosis regulator, homolog (Drosophila).	0.927
H2M111_ORYLA	rictor	ENSORLP00000012090	ENSORLP00000016159	Uncharacterized protein.	RPTOR independent companion of MTOR, complex 2 a.	0.447
H2M111_ORYLA	rptor	ENSORLP00000012090	ENSORLP00000031829	Uncharacterized protein.	Regulatory associated protein of MTOR, complex 1.	0.996
H2M111_ORYLA	rragc	ENSORLP00000012090	ENSORLP00000018472	Uncharacterized protein.	Ras-related GTP binding Ca.	0.901
H2M111_ORYLA	sec13	ENSORLP00000012090	ENSORLP00000024783	Uncharacterized protein.	SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.	0.699
H2M111_ORYLA	seh1l	ENSORLP00000012090	ENSORLP00000004083	Uncharacterized protein.	SEH1-like (S. cerevisiae); Belongs to the WD repeat SEC13 family.	0.735
H2M111_ORYLA	slc38a9	ENSORLP00000012090	ENSORLP00000019343	Uncharacterized protein.	Solute carrier family 38 member 9.	0.916