(9 nodes) Response to fluid shear stress network (Oryzias latipes)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	xbp1	X-box binding protein 1. (259 aa)
	pkd1	Uncharacterized protein. (4114 aa)
	ptgs2	EGF-like domain-containing protein. (607 aa)
	nfe2l2	Nuclear factor, erythroid 2-like 2a. (605 aa)
	smad6	Mothers against decapentaplegic homolog. (488 aa)
	LOC101170165	Mothers against decapentaplegic homolog. (499 aa)
	ubiad1	UbiA prenyltransferase domain containing 1. (405 aa)
	smad7	Mothers against decapentaplegic homolog. (375 aa)
	pkd2	Polycystin-2; Component of a heteromeric calcium-permeable ion channel formed by PKD1 and PKD2 that is activated by interaction between PKD1 and a Wnt family member, such as WNT3A and WNT9B. Can also form a functional, homotetrameric ion channel (By similarity). Functions as non-selective, voltage-gated cation channel. Required for normal oscillation of Ca(2+) levels within cilia; these oscillations of the intraciliary Ca(2+) levels can trigger cytoplasmic Ca(2+) signaling cascades (By similarity). May contribute to the release of Ca(2+) stores from the endoplasmic reticulum (By simila [...] (946 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101170165	smad6	ENSORLP00000002767	ENSORLP00000008572	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.906
LOC101170165	smad7	ENSORLP00000002767	ENSORLP00000044215	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.908
pkd1	pkd2	ENSORLP00000024551	ENSORLP00000031188	Uncharacterized protein.	Polycystin-2; Component of a heteromeric calcium-permeable ion channel formed by PKD1 and PKD2 that is activated by interaction between PKD1 and a Wnt family member, such as WNT3A and WNT9B. Can also form a functional, homotetrameric ion channel (By similarity). Functions as non-selective, voltage-gated cation channel. Required for normal oscillation of Ca(2+) levels within cilia; these oscillations of the intraciliary Ca(2+) levels can trigger cytoplasmic Ca(2+) signaling cascades (By similarity). May contribute to the release of Ca(2+) stores from the endoplasmic reticulum (By simila [...]	0.956
pkd2	pkd1	ENSORLP00000031188	ENSORLP00000024551	Polycystin-2; Component of a heteromeric calcium-permeable ion channel formed by PKD1 and PKD2 that is activated by interaction between PKD1 and a Wnt family member, such as WNT3A and WNT9B. Can also form a functional, homotetrameric ion channel (By similarity). Functions as non-selective, voltage-gated cation channel. Required for normal oscillation of Ca(2+) levels within cilia; these oscillations of the intraciliary Ca(2+) levels can trigger cytoplasmic Ca(2+) signaling cascades (By similarity). May contribute to the release of Ca(2+) stores from the endoplasmic reticulum (By simila [...]	Uncharacterized protein.	0.956
smad6	LOC101170165	ENSORLP00000008572	ENSORLP00000002767	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.906
smad6	smad7	ENSORLP00000008572	ENSORLP00000044215	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.908
smad7	LOC101170165	ENSORLP00000044215	ENSORLP00000002767	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.908
smad7	smad6	ENSORLP00000044215	ENSORLP00000008572	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.908