(57 nodes) Multicellular organism growth network (Oryzias latipes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	taf10	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (186 aa)
	sp2	Sp2 transcription factor. (636 aa)
	tal2	T-cell acute lymphocytic leukemia 2. (112 aa)
	H2L4B7_ORYLA	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (737 aa)
	Mtor	Serine/threonine-protein kinase TOR. (1023 aa)
	LOC101160301	Amino acid transporter. (527 aa)
	LOC101167791	Amino acid transporter. (663 aa)
	LOC101160197	E1A binding protein p300 a. (2781 aa)
	SLITRK1	SLIT and NTRK like family member 1. (693 aa)
	slitrk6	SLIT and NTRK-like family, member 6. (801 aa)
	LOC101161131	Lysine (K)-specific demethylase 6A, like. (1465 aa)
	fkbp8	Peptidylprolyl isomerase. (401 aa)
	ankrd11	Ankyrin repeat domain 11. (2833 aa)
	atrx	ATRX chromatin remodeler. (2095 aa)
	LOC101173635	Selenoprotein M. (147 aa)
	LOC101175499	Activating transcription factor 5a. (503 aa)
	ar-alpha	Uncharacterized protein. (687 aa)
	LOC101171430	Uncharacterized protein. (1871 aa)
	LOC100049233	Androgen receptor beta subtype. (744 aa)
	LOC101170530	Ring finger and CCCH-type domains 2. (1143 aa)
	slc1a2	Amino acid transporter. (526 aa)
	wdr11	WD repeat domain 11. (1209 aa)
	H2ME95_ORYLA	Lysine (K)-specific demethylase 6A. (806 aa)
	LOC101166648	Amyloid beta (A4) precursor protein-binding, family A, member 1b. (1077 aa)
	smo	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (828 aa)
	zmpste24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (467 aa)
	ercc1	Excision repair cross-complementation group 1. (341 aa)
	ttc8	Tetratricopeptide repeat domain 8. (505 aa)
	LOC101172728	Tensin 2b. (1541 aa)
	LOC101168719	Uncharacterized protein. (185 aa)
	en1	Homeobox protein engrailed-like. (280 aa)
	Atm	Uncharacterized protein. (147 aa)
	ankrd12	Ankyrin repeat domain 12. (1906 aa)
	ENSORLP00000027619	TAN domain-containing protein. (321 aa)
	LOC101161906	Transmembrane p24 trafficking protein 2. (207 aa)
	wdtc1	WD and tetratricopeptide repeats 1. (674 aa)
	ENSORLP00000030299	DWNN domain-containing protein. (129 aa)
	LOC101163680	Activating transcription factor 5b. (504 aa)
	LOC101165700	Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1b. (306 aa)
	LOC105354225	Peptidylprolyl isomerase. (474 aa)
	ercc2	Excision repair cross-complementation group 2. (761 aa)
	LOC101168870	E1A binding protein p300 b. (2760 aa)
	rbbp6	RING-type domain-containing protein. (1344 aa)
	apba2	Amyloid beta (A4) precursor protein-binding, family A, member 2b. (919 aa)
	Unc79	Uncharacterized protein. (152 aa)
	pkdcc	Protein kinase domain containing, cytoplasmic b. (473 aa)
	ENSORLP00000039316	Uncharacterized protein. (281 aa)
	stk40	Serine/threonine kinase 40. (442 aa)
	LOC101160962	Uncharacterized protein. (1887 aa)
	ercc6	Excision repair cross-complementation group 6. (1342 aa)
	LOC101160001	ANK_REP_REGION domain-containing protein. (658 aa)
	LOC101160976	Amyloid beta (A4) precursor protein-binding, family A, member 2a. (820 aa)
	LOC101163390	Uncharacterized protein. (537 aa)
	palb2	PALB2_WD40 domain-containing protein. (1311 aa)
	smpd3	Sphingomyelin phosphodiesterase 3, neutral. (716 aa)
	tns2	Tensin 2a. (1822 aa)
	xrcc2	X-ray repair cross complementing 2. (313 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Atm	ENSORLP00000027619	ENSORLP00000026266	ENSORLP00000027619	Uncharacterized protein.	TAN domain-containing protein.	0.929
Atm	H2L4B7_ORYLA	ENSORLP00000026266	ENSORLP00000000606	Uncharacterized protein.	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	0.787
Atm	LOC101160001	ENSORLP00000026266	ENSORLP00000042806	Uncharacterized protein.	ANK_REP_REGION domain-containing protein.	0.488
Atm	LOC101171430	ENSORLP00000026266	ENSORLP00000011523	Uncharacterized protein.	Uncharacterized protein.	0.418
Atm	Mtor	ENSORLP00000026266	ENSORLP00000000608	Uncharacterized protein.	Serine/threonine-protein kinase TOR.	0.528
Atm	ankrd11	ENSORLP00000026266	ENSORLP00000007162	Uncharacterized protein.	Ankyrin repeat domain 11.	0.488
Atm	ankrd12	ENSORLP00000026266	ENSORLP00000026628	Uncharacterized protein.	Ankyrin repeat domain 12.	0.488
Atm	atrx	ENSORLP00000026266	ENSORLP00000007639	Uncharacterized protein.	ATRX chromatin remodeler.	0.418
Atm	ercc1	ENSORLP00000026266	ENSORLP00000020313	Uncharacterized protein.	Excision repair cross-complementation group 1.	0.574
Atm	ercc2	ENSORLP00000026266	ENSORLP00000032234	Uncharacterized protein.	Excision repair cross-complementation group 2.	0.719
Atm	palb2	ENSORLP00000026266	ENSORLP00000043989	Uncharacterized protein.	PALB2_WD40 domain-containing protein.	0.680
Atm	xrcc2	ENSORLP00000026266	ENSORLP00000045844	Uncharacterized protein.	X-ray repair cross complementing 2.	0.682
ENSORLP00000027619	Atm	ENSORLP00000027619	ENSORLP00000026266	TAN domain-containing protein.	Uncharacterized protein.	0.929
ENSORLP00000027619	H2L4B7_ORYLA	ENSORLP00000027619	ENSORLP00000000606	TAN domain-containing protein.	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	0.804
ENSORLP00000027619	LOC101160001	ENSORLP00000027619	ENSORLP00000042806	TAN domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.488
ENSORLP00000027619	LOC101171430	ENSORLP00000027619	ENSORLP00000011523	TAN domain-containing protein.	Uncharacterized protein.	0.418
ENSORLP00000027619	Mtor	ENSORLP00000027619	ENSORLP00000000608	TAN domain-containing protein.	Serine/threonine-protein kinase TOR.	0.528
ENSORLP00000027619	ankrd11	ENSORLP00000027619	ENSORLP00000007162	TAN domain-containing protein.	Ankyrin repeat domain 11.	0.488
ENSORLP00000027619	ankrd12	ENSORLP00000027619	ENSORLP00000026628	TAN domain-containing protein.	Ankyrin repeat domain 12.	0.488
ENSORLP00000027619	atrx	ENSORLP00000027619	ENSORLP00000007639	TAN domain-containing protein.	ATRX chromatin remodeler.	0.418