(22 nodes) Positive regulation of protein dephosphorylation network (Oryzias latipes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cdca2	PP1-binding domain-containing protein. (758 aa)
	LOC101174288	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (781 aa)
	smpd1	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (604 aa)
	LOC101174201	Angiotensin II receptor, type 2; Belongs to the G-protein coupled receptor 1 family. (418 aa)
	LOC101157631	Transforming growth factor beta; Belongs to the TGF-beta family. (444 aa)
	sppl3	Signal peptide peptidase 3. (383 aa)
	gba	Glucosylceramidase. (522 aa)
	cnep1r1	CTD nuclear envelope phosphatase 1 regulatory subunit 1. (115 aa)
	ambra1	Autophagy/beclin-1 regulator 1b. (1376 aa)
	sympk	Symplekin. (1212 aa)
	pink1	PTEN induced kinase 1. (577 aa)
	magi2	Membrane associated guanylate kinase, WW and PDZ domain containing 2a. (1331 aa)
	ppp1r7	Protein phosphatase 1, regulatory (inhibitor) subunit 7. (385 aa)
	ptpa	Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (324 aa)
	LOC101162120	Protein phosphatase 1, regulatory subunit 15B. (555 aa)
	tmem130	Transmembrane protein 130. (311 aa)
	vrk3	VRK serine/threonine kinase 3. (510 aa)
	LRRC43	Leucine rich repeat containing 43. (597 aa)
	LOC101173221	Membrane associated guanylate kinase, WW and PDZ domain containing 2b. (1528 aa)
	ptprc	Protein tyrosine phosphatase receptor type C. (1343 aa)
	ppp1r42	Protein phosphatase 1, regulatory subunit 42. (274 aa)
	ankle2	Ankyrin repeat and LEM domain containing 2. (966 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101162120	LRRC43	ENSORLP00000029487	ENSORLP00000034285	Protein phosphatase 1, regulatory subunit 15B.	Leucine rich repeat containing 43.	0.540
LOC101174288	ptprc	ENSORLP00000001587	ENSORLP00000035490	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	Protein tyrosine phosphatase receptor type C.	0.491
LRRC43	LOC101162120	ENSORLP00000034285	ENSORLP00000029487	Leucine rich repeat containing 43.	Protein phosphatase 1, regulatory subunit 15B.	0.540
gba	pink1	ENSORLP00000012639	ENSORLP00000020035	Glucosylceramidase.	PTEN induced kinase 1.	0.638
gba	smpd1	ENSORLP00000012639	ENSORLP00000005827	Glucosylceramidase.	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.	0.939
pink1	gba	ENSORLP00000020035	ENSORLP00000012639	PTEN induced kinase 1.	Glucosylceramidase.	0.638
ptprc	LOC101174288	ENSORLP00000035490	ENSORLP00000001587	Protein tyrosine phosphatase receptor type C.	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	0.491
smpd1	gba	ENSORLP00000005827	ENSORLP00000012639	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.	Glucosylceramidase.	0.939
smpd1	tmem130	ENSORLP00000005827	ENSORLP00000030529	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.	Transmembrane protein 130.	0.416
tmem130	smpd1	ENSORLP00000030529	ENSORLP00000005827	Transmembrane protein 130.	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.	0.416