STRINGSTRING
LOC111949269 LOC111949269 LOC101164385 LOC101164385 LOC101157631 LOC101157631 Fgf1 Fgf1 LOC101165892 LOC101165892 LOC101159013 LOC101159013 H2L9W7_ORYLA H2L9W7_ORYLA map2k5 map2k5 pik3r5 pik3r5 Fzd8 Fzd8 axin1 axin1 LOC101161650 LOC101161650 LOC101172518 LOC101172518 htr2b htr2b tenm1 tenm1 pdgfa pdgfa LOC101162428 LOC101162428 ern1 ern1 edn1 edn1 pik3cg pik3cg H2M3J6_ORYLA H2M3J6_ORYLA LOC101171139 LOC101171139 LOC101172593 LOC101172593 fzd4 fzd4 nox4 nox4 LOC101165149 LOC101165149 LOC101168659 LOC101168659 sash1 sash1 fgfr1 fgfr1 PIK3R5 PIK3R5 nek10 nek10 LOC101173126 LOC101173126 lrrk2 lrrk2 LOC101173120 LOC101173120 pdgfb pdgfb map3k7 map3k7 LOC101160820 LOC101160820 vegfa vegfa map3k13 map3k13 tpd52l1 tpd52l1 map2k7 map2k7 LOC100301586 LOC100301586 SAMD5-2 SAMD5-2 LOC101169592 LOC101169592 pdcd10 pdcd10 ptprc ptprc pdgfc pdgfc ENSORLP00000036607 ENSORLP00000036607 LOC101169209 LOC101169209 LOC101166855 LOC101166855 map3k4 map3k4 ajuba ajuba LOC101155494 LOC101155494 fgf18 fgf18 il34 il34 tnfrsf11a tnfrsf11a LOC105356874 LOC105356874
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC111949269Uncharacterized protein. (927 aa)
LOC101164385Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (383 aa)
LOC101157631Transforming growth factor beta; Belongs to the TGF-beta family. (444 aa)
Fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (159 aa)
LOC101165892EGF-like domain-containing protein. (162 aa)
LOC101159013Si:rp71-17i16.5; Belongs to the PI3/PI4-kinase family. (1106 aa)
H2L9W7_ORYLAUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
map2k5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (445 aa)
pik3r5Phosphoinositide-3-kinase, regulatory subunit 5. (883 aa)
Fzd8Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. (573 aa)
axin1Axin 1. (854 aa)
LOC101161650Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (157 aa)
LOC101172518Dickkopf WNT signaling pathway inhibitor 1a. (244 aa)
htr2b5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled. (473 aa)
tenm1Teneurin transmembrane protein 1. (2760 aa)
pdgfaPlatelet-derived growth factor alpha polypeptide b; Belongs to the PDGF/VEGF growth factor family. (227 aa)
LOC101162428Endoplasmic reticulum to nucleus signaling 2. (963 aa)
ern1Uncharacterized protein. (1071 aa)
edn1Endothelin 1. (220 aa)
pik3cgPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1121 aa)
H2M3J6_ORYLAUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (564 aa)
LOC101171139Platelet-derived growth factor alpha polypeptide a; Belongs to the PDGF/VEGF growth factor family. (199 aa)
LOC101172593Tumor necrosis factor a (TNF superfamily, member 2). (279 aa)
fzd4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (529 aa)
nox4FAD-binding FR-type domain-containing protein. (556 aa)
LOC101165149Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (510 aa)
LOC101168659Dual specificity phosphatase 19a. (207 aa)
sash1SAM and SH3 domain containing 1a. (1225 aa)
fgfr1Fibroblast growth factor receptor. (833 aa)
PIK3R5Phosphoinositide-3-kinase regulatory subunit 5. (861 aa)
nek10NIMA-related kinase 10. (998 aa)
LOC101173126Dopamine receptor D4a; Belongs to the G-protein coupled receptor 1 family. (382 aa)
lrrk2Leucine-rich repeat kinase 2. (2241 aa)
LOC101173120G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (390 aa)
pdgfbPlatelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (553 aa)
map3k7Mitogen-activated protein kinase kinase kinase 7. (595 aa)
LOC101160820SCY domain-containing protein. (131 aa)
vegfaVascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (214 aa)
map3k13Mitogen-activated protein kinase kinase kinase. (1002 aa)
tpd52l1Tpd52 like 1. (220 aa)
map2k7Mitogen-activated protein kinase kinase 7. (477 aa)
LOC100301586CD40 molecule, TNF receptor superfamily member 5. (305 aa)
SAMD5-2SAM domain-containing protein. (178 aa)
LOC101169592Dual specificity phosphatase 19b. (208 aa)
pdcd10Programmed cell death 10b. (210 aa)
ptprcProtein tyrosine phosphatase receptor type C. (1343 aa)
pdgfcPlatelet derived growth factor c; Belongs to the PDGF/VEGF growth factor family. (342 aa)
ENSORLP00000036607Uncharacterized protein. (251 aa)
LOC101169209Uncharacterized protein. (283 aa)
LOC101166855Transforming growth factor, alpha. (254 aa)
map3k4Mitogen-activated protein kinase kinase kinase 4. (1590 aa)
ajubaAjuba. (694 aa)
LOC101155494Uncharacterized protein. (883 aa)
fgf18Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
il34Interleukin 34. (236 aa)
tnfrsf11aTumor necrosis factor receptor superfamily, member 11a, NFKB activator. (639 aa)
LOC105356874Protein kinase domain-containing protein. (501 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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