(21 nodes) Regulation of viral genome replication network (Oryzias latipes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ddb1	Damage-specific DNA binding protein 1. (1126 aa)
	LOC101164979	Transcription activation suppressor b. (1819 aa)
	adar	Adenosine deaminase RNA specific. (1336 aa)
	LOC101172593	Tumor necrosis factor a (TNF superfamily, member 2). (279 aa)
	morc2	MORC family CW-type zinc finger 2. (847 aa)
	LOC100144382	Eukaryotic translation initiation factor 2-alpha kinase 2. (638 aa)
	H2MEC6_ORYLA	Poly [ADP-ribose] polymerase. (359 aa)
	bcl2	BCL2 apoptosis regulator b. (202 aa)
	ifih1	Interferon induced with helicase C domain 1. (974 aa)
	pde12	Phosphodiesterase 12. (589 aa)
	ppie	Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (313 aa)
	fkbp6	Peptidylprolyl isomerase. (338 aa)
	LOC110016550	Eukaryotic translation initiation factor 2-alpha kinase 2. (678 aa)
	aicda	Activation-induced cytidine deaminase. (211 aa)
	top2b	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1599 aa)
	ppid	Peptidylprolyl isomerase D. (379 aa)
	mphosph8	Uncharacterized protein. (867 aa)
	LOC101155422	Uncharacterized protein. (115 aa)
	n4bp1	Nedd4 binding protein 1. (996 aa)
	znfx1	Zinc finger, NFX1-type containing 1. (1904 aa)
	top2a	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1571 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC100144382	adar	ENSORLP00000015562	ENSORLP00000012489	Eukaryotic translation initiation factor 2-alpha kinase 2.	Adenosine deaminase RNA specific.	0.582
LOC100144382	ifih1	ENSORLP00000015562	ENSORLP00000021147	Eukaryotic translation initiation factor 2-alpha kinase 2.	Interferon induced with helicase C domain 1.	0.765
LOC101164979	mphosph8	ENSORLP00000012333	ENSORLP00000038582	Transcription activation suppressor b.	Uncharacterized protein.	0.773
LOC101172593	bcl2	ENSORLP00000013121	ENSORLP00000021005	Tumor necrosis factor a (TNF superfamily, member 2).	BCL2 apoptosis regulator b.	0.572
LOC110016550	adar	ENSORLP00000023678	ENSORLP00000012489	Eukaryotic translation initiation factor 2-alpha kinase 2.	Adenosine deaminase RNA specific.	0.582
LOC110016550	ifih1	ENSORLP00000023678	ENSORLP00000021147	Eukaryotic translation initiation factor 2-alpha kinase 2.	Interferon induced with helicase C domain 1.	0.765
adar	LOC100144382	ENSORLP00000012489	ENSORLP00000015562	Adenosine deaminase RNA specific.	Eukaryotic translation initiation factor 2-alpha kinase 2.	0.582
adar	LOC110016550	ENSORLP00000012489	ENSORLP00000023678	Adenosine deaminase RNA specific.	Eukaryotic translation initiation factor 2-alpha kinase 2.	0.582
adar	aicda	ENSORLP00000012489	ENSORLP00000026417	Adenosine deaminase RNA specific.	Activation-induced cytidine deaminase.	0.403
adar	ifih1	ENSORLP00000012489	ENSORLP00000021147	Adenosine deaminase RNA specific.	Interferon induced with helicase C domain 1.	0.576
adar	znfx1	ENSORLP00000012489	ENSORLP00000007662	Adenosine deaminase RNA specific.	Zinc finger, NFX1-type containing 1.	0.641
aicda	adar	ENSORLP00000026417	ENSORLP00000012489	Activation-induced cytidine deaminase.	Adenosine deaminase RNA specific.	0.403
bcl2	LOC101172593	ENSORLP00000021005	ENSORLP00000013121	BCL2 apoptosis regulator b.	Tumor necrosis factor a (TNF superfamily, member 2).	0.572
ifih1	LOC100144382	ENSORLP00000021147	ENSORLP00000015562	Interferon induced with helicase C domain 1.	Eukaryotic translation initiation factor 2-alpha kinase 2.	0.765
ifih1	LOC110016550	ENSORLP00000021147	ENSORLP00000023678	Interferon induced with helicase C domain 1.	Eukaryotic translation initiation factor 2-alpha kinase 2.	0.765
ifih1	adar	ENSORLP00000021147	ENSORLP00000012489	Interferon induced with helicase C domain 1.	Adenosine deaminase RNA specific.	0.576
mphosph8	LOC101164979	ENSORLP00000038582	ENSORLP00000012333	Uncharacterized protein.	Transcription activation suppressor b.	0.773
ppid	ppie	ENSORLP00000037163	ENSORLP00000021843	Peptidylprolyl isomerase D.	Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.	0.473
ppie	ppid	ENSORLP00000021843	ENSORLP00000037163	Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.	Peptidylprolyl isomerase D.	0.473
znfx1	adar	ENSORLP00000007662	ENSORLP00000012489	Zinc finger, NFX1-type containing 1.	Adenosine deaminase RNA specific.	0.641