(56 nodes) Fat cell differentiation network (Oryzias latipes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ctbp1	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (443 aa)
	ENSORLP00000033347	CCAAT enhancer binding protein delta. (138 aa)
	LOC101171058	Uncharacterized protein. (566 aa)
	LOC101162856	Transmembrane protein 120B. (338 aa)
	ENSORLP00000034403	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (1540 aa)
	cby1	Chibby homolog 1 (Drosophila). (134 aa)
	nr4a1	Nuclear receptor subfamily 4, group A, member 1. (571 aa)
	LOC101155940	BSCL2 lipid droplet biogenesis associated, seipin, like. (365 aa)
	LOC101155422	Uncharacterized protein. (115 aa)
	ENSORLP00000039466	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (1375 aa)
	LOC101169730	G_PROTEIN_RECEP_F1_2 domain-containing protein. (332 aa)
	ctbp2	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (458 aa)
	trim32	Tripartite motif containing 32. (622 aa)
	Plac8	Placenta associated 8, tandem duplicate 1. (96 aa)
	prdm16	Si:ch211-263k4.2. (1400 aa)
	socs1	Suppressor of cytokine signaling 1. (199 aa)
	med1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1782 aa)
	nr4a3	Nuclear receptor subfamily 4, group A, member 3. (612 aa)
	ENSORLP00000043858	Si:ch211-272n13.3. (250 aa)
	ENSORLP00000044390	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (1450 aa)
	LOC101168870	E1A binding protein p300 b. (2760 aa)
	LOC101160989	Zinc finger protein 516. (879 aa)
	LOC101163680	Activating transcription factor 5b. (504 aa)
	ENSORLP00000030280	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (303 aa)
	LOC101165550	Uncharacterized protein. (585 aa)
	LOC101158320	Aldedh domain-containing protein. (527 aa)
	ZNF516	Zinc finger protein 516. (1055 aa)
	fam120b	Family with sequence similarity 120B. (727 aa)
	bbs1	Bardet-Biedl syndrome 1. (583 aa)
	bbs7	Bardet-Biedl syndrome 7. (714 aa)
	nr4a2	Nuclear receptor subfamily 4, group A, member 2b. (600 aa)
	LOC101166126	BSCL2 lipid droplet biogenesis associated, seipin. (394 aa)
	ttc8	Tetratricopeptide repeat domain 8. (505 aa)
	aldh6a1	Aldehyde dehydrogenase 6 family member A1. (525 aa)
	bbs9	Bardet-Biedl syndrome 9. (998 aa)
	LOC101155601	CCAAT enhancer binding protein beta. (286 aa)
	LOC101172185	Transmembrane protein 120A. (347 aa)
	sirt1	Deacetylase sirtuin-type domain-containing protein. (680 aa)
	H2MBJ4_ORYLA	Uncharacterized protein. (306 aa)
	mkks	McKusick-Kaufman syndrome. (564 aa)
	dhrs7b	Dehydrogenase/reductase (SDR family) member 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (325 aa)
	LOC101173961	Zgc:103681. (337 aa)
	cntn2	Contactin 2. (1034 aa)
	lamb3	Uncharacterized protein. (1255 aa)
	ptgs2	EGF-like domain-containing protein. (607 aa)
	steap4	STEAP family member 4. (472 aa)
	LOC101175499	Activating transcription factor 5a. (503 aa)
	LOC101170279	Adrenoceptor beta 2, surface a. (415 aa)
	Retreg1	Reticulophagy regulator 1. (351 aa)
	LOC101168811	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (448 aa)
	LOC101158706	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (448 aa)
	Adrb1	Adrenoceptor beta 1. (403 aa)
	LOC101160197	E1A binding protein p300 a. (2781 aa)
	Ankrd26	CCDC144C domain-containing protein. (283 aa)
	H2L8Z5_ORYLA	DUF3496 domain-containing protein. (481 aa)
	bbs4	Bardet-Biedl syndrome 4. (535 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Adrb1	LOC101170279	ENSORLP00000006043	ENSORLP00000009383	Adrenoceptor beta 1.	Adrenoceptor beta 2, surface a.	0.503
Ankrd26	ENSORLP00000043858	ENSORLP00000002329	ENSORLP00000043858	CCDC144C domain-containing protein.	Si:ch211-272n13.3.	0.893
Ankrd26	H2L8Z5_ORYLA	ENSORLP00000002329	ENSORLP00000002328	CCDC144C domain-containing protein.	DUF3496 domain-containing protein.	0.880
ENSORLP00000033347	LOC101155601	ENSORLP00000033347	ENSORLP00000018839	CCAAT enhancer binding protein delta.	CCAAT enhancer binding protein beta.	0.824
ENSORLP00000033347	LOC101163680	ENSORLP00000033347	ENSORLP00000030861	CCAAT enhancer binding protein delta.	Activating transcription factor 5b.	0.438
ENSORLP00000033347	LOC101175499	ENSORLP00000033347	ENSORLP00000009479	CCAAT enhancer binding protein delta.	Activating transcription factor 5a.	0.438
ENSORLP00000043858	Ankrd26	ENSORLP00000043858	ENSORLP00000002329	Si:ch211-272n13.3.	CCDC144C domain-containing protein.	0.893
ENSORLP00000043858	H2L8Z5_ORYLA	ENSORLP00000043858	ENSORLP00000002328	Si:ch211-272n13.3.	DUF3496 domain-containing protein.	0.825
H2L8Z5_ORYLA	Ankrd26	ENSORLP00000002328	ENSORLP00000002329	DUF3496 domain-containing protein.	CCDC144C domain-containing protein.	0.880
H2L8Z5_ORYLA	ENSORLP00000043858	ENSORLP00000002328	ENSORLP00000043858	DUF3496 domain-containing protein.	Si:ch211-272n13.3.	0.825
LOC101155601	ENSORLP00000033347	ENSORLP00000018839	ENSORLP00000033347	CCAAT enhancer binding protein beta.	CCAAT enhancer binding protein delta.	0.824
LOC101155601	LOC101160197	ENSORLP00000018839	ENSORLP00000003103	CCAAT enhancer binding protein beta.	E1A binding protein p300 a.	0.738
LOC101155601	LOC101163680	ENSORLP00000018839	ENSORLP00000030861	CCAAT enhancer binding protein beta.	Activating transcription factor 5b.	0.446
LOC101155601	LOC101168870	ENSORLP00000018839	ENSORLP00000032567	CCAAT enhancer binding protein beta.	E1A binding protein p300 b.	0.738
LOC101155601	LOC101175499	ENSORLP00000018839	ENSORLP00000009479	CCAAT enhancer binding protein beta.	Activating transcription factor 5a.	0.446
LOC101155601	prdm16	ENSORLP00000018839	ENSORLP00000041247	CCAAT enhancer binding protein beta.	Si:ch211-263k4.2.	0.731
LOC101158320	aldh6a1	ENSORLP00000027073	ENSORLP00000020416	Aldedh domain-containing protein.	Aldehyde dehydrogenase 6 family member A1.	0.900
LOC101158706	LOC101160989	ENSORLP00000006778	ENSORLP00000031157	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Zinc finger protein 516.	0.428
LOC101158706	ZNF516	ENSORLP00000006778	ENSORLP00000026307	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Zinc finger protein 516.	0.428
LOC101158706	med1	ENSORLP00000006778	ENSORLP00000043584	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.435