10 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Fgf1	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (159 aa)
	LOC101161259	ATP-binding cassette, sub-family G (WHITE), member 4a. (642 aa)
	srebf1	Sterol regulatory element binding transcription factor 1. (1159 aa)
	rusc1	Uncharacterized protein. (1876 aa)
	abcg1	ATP-binding cassette, sub-family G (WHITE), member 1. (639 aa)
	scap	SREBF chaperone. (1355 aa)
	LOC101164423	ABC transporter domain-containing protein. (648 aa)
	srebf2	Sterol regulatory element binding transcription factor 2. (1179 aa)
	podn	Podocan. (614 aa)
	LOC101161650	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (157 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101161259	LOC101164423	ENSORLP00000009370	ENSORLP00000019247	ATP-binding cassette, sub-family G (WHITE), member 4a.	ABC transporter domain-containing protein.	0.901
LOC101164423	LOC101161259	ENSORLP00000019247	ENSORLP00000009370	ABC transporter domain-containing protein.	ATP-binding cassette, sub-family G (WHITE), member 4a.	0.901
abcg1	srebf2	ENSORLP00000040993	ENSORLP00000018394	ATP-binding cassette, sub-family G (WHITE), member 1.	Sterol regulatory element binding transcription factor 2.	0.489
scap	srebf1	ENSORLP00000032248	ENSORLP00000011832	SREBF chaperone.	Sterol regulatory element binding transcription factor 1.	0.968
scap	srebf2	ENSORLP00000032248	ENSORLP00000018394	SREBF chaperone.	Sterol regulatory element binding transcription factor 2.	0.968
srebf1	scap	ENSORLP00000011832	ENSORLP00000032248	Sterol regulatory element binding transcription factor 1.	SREBF chaperone.	0.968
srebf1	srebf2	ENSORLP00000011832	ENSORLP00000018394	Sterol regulatory element binding transcription factor 1.	Sterol regulatory element binding transcription factor 2.	0.497
srebf2	abcg1	ENSORLP00000018394	ENSORLP00000040993	Sterol regulatory element binding transcription factor 2.	ATP-binding cassette, sub-family G (WHITE), member 1.	0.489
srebf2	scap	ENSORLP00000018394	ENSORLP00000032248	Sterol regulatory element binding transcription factor 2.	SREBF chaperone.	0.968
srebf2	srebf1	ENSORLP00000018394	ENSORLP00000011832	Sterol regulatory element binding transcription factor 2.	Sterol regulatory element binding transcription factor 1.	0.497