(15 nodes) Regulation of T-helper cell differentiation network (Oryzias latipes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSORLP00000045949	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta. (274 aa)
	LOC101171170	MALT paracaspase 1. (811 aa)
	LOC101158194	MALT paracaspase 3. (557 aa)
	LOC101158686	MALT paracaspase 2. (843 aa)
	tbx21	T-box transcription factor 21. (619 aa)
	LOC101160820	SCY domain-containing protein. (131 aa)
	myb	Uncharacterized protein. (592 aa)
	LOC101158138	Ring finger and CCCH-type domains 1b. (1116 aa)
	LOC101170545	Zinc finger CCCH-type containing 12A. (621 aa)
	hlx	H2.0-like homeo box 1 (Drosophila). (387 aa)
	LOC101170530	Ring finger and CCCH-type domains 2. (1143 aa)
	ZC3H12A	Zinc finger CCCH-type containing 12A. (270 aa)
	ripk2	Receptor-interacting serine-threonine kinase 2. (590 aa)
	nfkbid	ANK_REP_REGION domain-containing protein. (453 aa)
	H2L4N6_ORYLA	Uncharacterized protein. (780 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSORLP00000045949	LOC101170545	ENSORLP00000045949	ENSORLP00000018100	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta.	Zinc finger CCCH-type containing 12A.	0.423
ENSORLP00000045949	ZC3H12A	ENSORLP00000045949	ENSORLP00000011872	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta.	Zinc finger CCCH-type containing 12A.	0.423
H2L4N6_ORYLA	ripk2	ENSORLP00000000732	ENSORLP00000010554	Uncharacterized protein.	Receptor-interacting serine-threonine kinase 2.	0.435
LOC101158138	LOC101170530	ENSORLP00000020077	ENSORLP00000012569	Ring finger and CCCH-type domains 1b.	Ring finger and CCCH-type domains 2.	0.673
LOC101170530	LOC101158138	ENSORLP00000012569	ENSORLP00000020077	Ring finger and CCCH-type domains 2.	Ring finger and CCCH-type domains 1b.	0.673
LOC101170545	ENSORLP00000045949	ENSORLP00000018100	ENSORLP00000045949	Zinc finger CCCH-type containing 12A.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta.	0.423
ZC3H12A	ENSORLP00000045949	ENSORLP00000011872	ENSORLP00000045949	Zinc finger CCCH-type containing 12A.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta.	0.423
hlx	tbx21	ENSORLP00000015094	ENSORLP00000032374	H2.0-like homeo box 1 (Drosophila).	T-box transcription factor 21.	0.565
ripk2	H2L4N6_ORYLA	ENSORLP00000010554	ENSORLP00000000732	Receptor-interacting serine-threonine kinase 2.	Uncharacterized protein.	0.435
tbx21	hlx	ENSORLP00000032374	ENSORLP00000015094	T-box transcription factor 21.	H2.0-like homeo box 1 (Drosophila).	0.565