(20 nodes) Regulation of osteoclast differentiation network (Oryzias latipes)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	H2L4B7_ORYLA	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (737 aa)
	Mtor	Serine/threonine-protein kinase TOR. (1023 aa)
	LOC101171801	G protein-coupled receptor 137Bb. (396 aa)
	TNFRSF11B	TNF receptor superfamily member 11b. (416 aa)
	LOC101172593	Tumor necrosis factor a (TNF superfamily, member 2). (279 aa)
	LOC101168287	Colony stimulating factor 1b (macrophage). (301 aa)
	LOC101159060	Leucine rich repeat containing 17. (456 aa)
	tfe3	Transcription factor binding to IGHM enhancer 3b. (512 aa)
	LOC101155601	CCAAT enhancer binding protein beta. (286 aa)
	ocstamp	Osteoclast stimulatory transmembrane protein. (466 aa)
	H2MJT0_ORYLA	Uncharacterized protein. (589 aa)
	inpp5d	Inositol polyphosphate-5-phosphatase D. (1092 aa)
	tnfaip6	Tumor necrosis factor, alpha-induced protein 6. (256 aa)
	Nf1	Uncharacterized protein. (506 aa)
	tmem178a	Transmembrane protein 178. (303 aa)
	MITF	Melanocyte inducing transcription factor b. (511 aa)
	LOC101169121	Peroxisome proliferator-activated receptor gamma, coactivator 1 beta. (924 aa)
	LOC101163732	Microphthalmia-associated transcription factor 2 isoform m. (406 aa)
	tmem64	Transmembrane protein 64. (352 aa)
	LOC101174799	BHLH domain-containing protein. (450 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H2L4B7_ORYLA	LOC101163732	ENSORLP00000000606	ENSORLP00000037247	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	Microphthalmia-associated transcription factor 2 isoform m.	0.479
H2L4B7_ORYLA	LOC101174799	ENSORLP00000000606	ENSORLP00000044809	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	BHLH domain-containing protein.	0.479
H2L4B7_ORYLA	MITF	ENSORLP00000000606	ENSORLP00000033348	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	Melanocyte inducing transcription factor b.	0.479
H2L4B7_ORYLA	Mtor	ENSORLP00000000606	ENSORLP00000000608	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	Serine/threonine-protein kinase TOR.	0.968
H2L4B7_ORYLA	tfe3	ENSORLP00000000606	ENSORLP00000017722	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	Transcription factor binding to IGHM enhancer 3b.	0.479
H2MJT0_ORYLA	Nf1	ENSORLP00000018929	ENSORLP00000026133	Uncharacterized protein.	Uncharacterized protein.	0.943
LOC101155601	LOC101172593	ENSORLP00000018839	ENSORLP00000013121	CCAAT enhancer binding protein beta.	Tumor necrosis factor a (TNF superfamily, member 2).	0.485
LOC101163732	H2L4B7_ORYLA	ENSORLP00000037247	ENSORLP00000000606	Microphthalmia-associated transcription factor 2 isoform m.	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	0.479
LOC101163732	MITF	ENSORLP00000037247	ENSORLP00000033348	Microphthalmia-associated transcription factor 2 isoform m.	Melanocyte inducing transcription factor b.	0.905
LOC101163732	Mtor	ENSORLP00000037247	ENSORLP00000000608	Microphthalmia-associated transcription factor 2 isoform m.	Serine/threonine-protein kinase TOR.	0.479
LOC101163732	tfe3	ENSORLP00000037247	ENSORLP00000017722	Microphthalmia-associated transcription factor 2 isoform m.	Transcription factor binding to IGHM enhancer 3b.	0.892
LOC101168287	LOC101172593	ENSORLP00000013158	ENSORLP00000013121	Colony stimulating factor 1b (macrophage).	Tumor necrosis factor a (TNF superfamily, member 2).	0.496
LOC101172593	LOC101155601	ENSORLP00000013121	ENSORLP00000018839	Tumor necrosis factor a (TNF superfamily, member 2).	CCAAT enhancer binding protein beta.	0.485
LOC101172593	LOC101168287	ENSORLP00000013121	ENSORLP00000013158	Tumor necrosis factor a (TNF superfamily, member 2).	Colony stimulating factor 1b (macrophage).	0.496
LOC101172593	tnfaip6	ENSORLP00000013121	ENSORLP00000023555	Tumor necrosis factor a (TNF superfamily, member 2).	Tumor necrosis factor, alpha-induced protein 6.	0.607
LOC101174799	H2L4B7_ORYLA	ENSORLP00000044809	ENSORLP00000000606	BHLH domain-containing protein.	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	0.479
LOC101174799	Mtor	ENSORLP00000044809	ENSORLP00000000608	BHLH domain-containing protein.	Serine/threonine-protein kinase TOR.	0.479
MITF	H2L4B7_ORYLA	ENSORLP00000033348	ENSORLP00000000606	Melanocyte inducing transcription factor b.	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	0.479
MITF	LOC101163732	ENSORLP00000033348	ENSORLP00000037247	Melanocyte inducing transcription factor b.	Microphthalmia-associated transcription factor 2 isoform m.	0.905
MITF	Mtor	ENSORLP00000033348	ENSORLP00000000608	Melanocyte inducing transcription factor b.	Serine/threonine-protein kinase TOR.	0.479