STRINGSTRING
lepa lepa H2L4B7_ORYLA H2L4B7_ORYLA Mtor Mtor agrn agrn anapc2 anapc2 sash3 sash3 bbs4 bbs4 ppib ppib LOC101160237 LOC101160237 slc44a4 slc44a4 map2k5 map2k5 LOC101155037 LOC101155037 bmpr2 bmpr2 zfpm2 zfpm2 LOC101155643 LOC101155643 n6amt1 n6amt1 LOC101172489 LOC101172489 ist1 ist1 LOC101164972 LOC101164972 hpn hpn LOC101164147 LOC101164147 LOC101156534 LOC101156534 LOC101157966 LOC101157966 islr2 islr2 sema7a sema7a exosc2 exosc2 usp47 usp47 wnt2bb wnt2bb adam10 adam10 sfrp2 sfrp2 LOC101157368 LOC101157368 ddx49 ddx49 LOC101158778 LOC101158778 edn1 edn1 1-sf 1-sf supv3l1 supv3l1 LOC101168287 LOC101168287 nsmf nsmf LOC101171428 LOC101171428 H2M7G4_ORYLA H2M7G4_ORYLA zfyve27 zfyve27 extl3 extl3 dbnl dbnl LOC101167158 LOC101167158 wnt3 wnt3 hlx hlx mkks mkks spast spast LOC101160424 LOC101160424 derl2 derl2 disc1 disc1 srf srf LOC100049402 LOC100049402 klhl22 klhl22 smo smo nol12 nol12 LOC101164044 LOC101164044 CDKL5 CDKL5 rftn1 rftn1 bcl2 bcl2 Zpr1 Zpr1 exosc4 exosc4 ino80 ino80 prkn prkn fgfr1op fgfr1op dbn1 dbn1 rufy3 rufy3 LOC101164215 LOC101164215 fn1 fn1 l1cam l1cam LOC101157206 LOC101157206 gpam gpam mul1 mul1 LOC101174300 LOC101174300 LOC101158526 LOC101158526 ghrh ghrh syt1 syt1 LOC101167425 LOC101167425 LOC101171344 LOC101171344 LOC101166797 LOC101166797 ENSORLP00000029926 ENSORLP00000029926 ppard ppard rptor rptor LOC105358811 LOC105358811 LOC101171477 LOC101171477 LOC101155634 LOC101155634 psmd10 psmd10 LOC101170246 LOC101170246 rnf157 rnf157 plaa plaa wnt3a wnt3a parp2 parp2 lgi1 lgi1 ucn ucn wfs1 wfs1 LOC101174816 LOC101174816 LOC101166116 LOC101166116 ENSORLP00000039626 ENSORLP00000039626 LOC101171872 LOC101171872 akap6 akap6 trim32 trim32 LOC101166140 LOC101166140 LOC101161806 LOC101161806 rusc1 rusc1 LOC105357487 LOC105357487 LOC101165277 LOC101165277 cib1 cib1 shtn1 shtn1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
lepaLeptin-A; May function as part of a signaling pathway that acts to regulate the size of the body fat depot. (185 aa)
H2L4B7_ORYLAMechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (737 aa)
MtorSerine/threonine-protein kinase TOR. (1023 aa)
agrnAgrin. (1950 aa)
anapc2Anaphase promoting complex subunit 2; Belongs to the cullin family. (802 aa)
sash3SAM and SH3 domain containing 3. (391 aa)
bbs4Bardet-Biedl syndrome 4. (535 aa)
ppibPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
LOC101160237Activity-dependent neuroprotector homeobox b. (1048 aa)
slc44a4Solute carrier family 44 member 4; Belongs to the CTL (choline transporter-like) family. (714 aa)
map2k5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (445 aa)
LOC101155037Transforming growth factor beta; Belongs to the TGF-beta family. (420 aa)
bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1056 aa)
zfpm2Zinc finger protein, FOG family member 2a. (1170 aa)
LOC101155643Rho family GTPase 2. (232 aa)
n6amt1N-6 adenine-specific DNA methyltransferase 1. (218 aa)
LOC101172489ADAM metallopeptidase domain 10b. (784 aa)
ist1IST1 factor associated with ESCRT-III. (346 aa)
LOC101164972Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
hpnHepsin; Belongs to the peptidase S1 family. (427 aa)
LOC101164147Nerve growth factor b (beta polypeptide); Belongs to the NGF-beta family. (198 aa)
LOC101156534Synaptotagmin Vb. (447 aa)
LOC101157966Leucine-rich, glioma inactivated 1a. (543 aa)
islr2Immunoglobulin superfamily containing leucine-rich repeat 2. (712 aa)
sema7aSemaphorin 7A; Belongs to the semaphorin family. (525 aa)
exosc2Exosome component 2. (293 aa)
usp47Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1365 aa)
wnt2bbProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
adam10Uncharacterized protein. (747 aa)
sfrp2Secreted frizzled-related protein 2. (290 aa)
LOC101157368Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family. (291 aa)
ddx49DEAD (Asp-Glu-Ala-Asp) box polypeptide 49; Belongs to the DEAD box helicase family. (469 aa)
LOC101158778COMM domain containing 5. (211 aa)
edn1Endothelin 1. (220 aa)
1-sfZP domain-containing protein. (420 aa)
supv3l1SUV3-like helicase. (779 aa)
LOC101168287Colony stimulating factor 1b (macrophage). (301 aa)
nsmfNMDA receptor synaptonuclear signaling and neuronal migration factor a. (618 aa)
LOC101171428FZ domain-containing protein. (337 aa)
H2M7G4_ORYLASi:dkey-280e21.3. (335 aa)
zfyve27Zinc finger, FYVE domain containing 27. (419 aa)
extl3Exostosin-like glycosyltransferase 3; Belongs to the glycosyltransferase 47 family. (915 aa)
dbnlDrebrin-like b. (390 aa)
LOC101167158Growth hormone secretagogue receptor b; Belongs to the G-protein coupled receptor 1 family. (430 aa)
wnt3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
hlxH2.0-like homeo box 1 (Drosophila). (387 aa)
mkksMcKusick-Kaufman syndrome. (564 aa)
spastSpastin; Belongs to the AAA ATPase family. (474 aa)
LOC101160424ADNP homeobox 2b. (1132 aa)
derl2Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
disc1DISC1 scaffold protein. (814 aa)
srfSerum response factor b. (611 aa)
LOC100049402Somatolactin; Selectively regulates proliferation and morphogenesis of neural-crest derived pigment cells; Belongs to the somatotropin/prolactin family. (230 aa)
klhl22Kelch-like family member 22. (621 aa)
smoSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (828 aa)
nol12Nucleolar protein 12. (230 aa)
LOC101164044Uncharacterized protein; Belongs to the semaphorin family. (665 aa)
CDKL5Cyclin dependent kinase like 5. (996 aa)
rftn1Uncharacterized protein. (616 aa)
bcl2BCL2 apoptosis regulator b. (202 aa)
Zpr1ZPR1 zinc finger. (454 aa)
exosc4Exosome component 4. (244 aa)
ino80INO80 complex ATPase subunit. (1547 aa)
prknE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (466 aa)
fgfr1opFOP_dimer domain-containing protein. (405 aa)
dbn1Drebrin 1. (602 aa)
rufy3RUN and FYVE domain containing 3. (673 aa)
LOC101164215Uncharacterized protein. (1289 aa)
fn1Fibronectin-1. (2503 aa)
l1camL1 cell adhesion molecule, paralog a. (1275 aa)
LOC101157206Uncharacterized protein. (430 aa)
gpamGlycerol-3-phosphate acyltransferase 1, mitochondrial. (823 aa)
mul1Mitochondrial E3 ubiquitin protein ligase 1b. (382 aa)
LOC101174300Parvalbumin 9; Belongs to the parvalbumin family. (158 aa)
LOC101158526Rho family GTPase 2. (234 aa)
ghrhGrowth hormone releasing hormone. (141 aa)
syt1Synaptotagmin Ia. (536 aa)
LOC101167425Wolfram syndrome 1a (wolframin). (1041 aa)
LOC101171344Raftlin, lipid raft linker 1a. (669 aa)
LOC101166797Parvalbumin 8; Belongs to the parvalbumin family. (122 aa)
ENSORLP00000029926Uncharacterized protein. (211 aa)
ppardUncharacterized protein. (517 aa)
rptorRegulatory associated protein of MTOR, complex 1. (1372 aa)
LOC105358811MADS-box domain-containing protein. (552 aa)
LOC101171477Uncharacterized protein; Belongs to the semaphorin family. (638 aa)
LOC101155634Si:ch211-113g11.6; Belongs to the semaphorin family. (637 aa)
psmd10Proteasome 26S subunit, non-ATPase 10. (226 aa)
LOC101170246Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (617 aa)
rnf157Ring finger protein 157. (697 aa)
plaaPhospholipase A2-activating protein. (797 aa)
wnt3aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
parp2Poly [ADP-ribose] polymerase. (649 aa)
lgi1Leucine-rich, glioma inactivated 1b. (553 aa)
ucnUrotensin 1. (132 aa)
wfs1Wolfram syndrome 1b (wolframin). (960 aa)
LOC101174816Cyclin-dependent kinase-like 5. (1153 aa)
LOC101166116CDKN2A interacting protein. (323 aa)
ENSORLP00000039626Frataxin. (185 aa)
LOC101171872ADAM metallopeptidase domain 17a. (850 aa)
akap6A kinase (PRKA) anchor protein 6. (2292 aa)
trim32Tripartite motif containing 32. (622 aa)
LOC101166140Si:dkey-40c11.2. (750 aa)
LOC101161806Synaptotagmin IIa. (432 aa)
rusc1Uncharacterized protein. (1876 aa)
LOC105357487Activin_recp domain-containing protein. (762 aa)
LOC101165277ADAM metallopeptidase domain 17b. (844 aa)
cib1Calcium and integrin binding 1 (calmyrin). (189 aa)
shtn1Shootin 1. (491 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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