(51 nodes) Protein N-terminus binding network (Oryzias latipes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101174813	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (384 aa)
	mau2	MAU2 sister chromatid cohesion factor. (598 aa)
	LOC101169275	MRG domain-containing protein. (335 aa)
	LOC101161547	Ras association domain family member 1. (570 aa)
	stx5	Syntaxin 5A; Belongs to the syntaxin family. (329 aa)
	SMARCE1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (427 aa)
	pex19	Peroxisomal biogenesis factor 19. (312 aa)
	ercc4	Excision repair cross-complementation group 4. (889 aa)
	RASSF1	Ras association domain family member 1. (364 aa)
	CFAP36	Cilia and flagella associated protein 36. (447 aa)
	LOC101155643	Rho family GTPase 2. (232 aa)
	ercc5	Excision repair cross-complementation group 5. (1078 aa)
	dctn4	Dynactin 4. (463 aa)
	LOC101168369	Charged multivesicular body protein 6a. (208 aa)
	LOC101171415	Synaptogyrin. (222 aa)
	LOC101164956	Synaptogyrin. (237 aa)
	alg2	ALG2 alpha-1,3/1,6-mannosyltransferase. (405 aa)
	scfd1	Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family. (631 aa)
	syngr1	Synaptogyrin 1a. (254 aa)
	men1	Multiple endocrine neoplasia I. (691 aa)
	LOC101157351	Synaptogyrin. (238 aa)
	snf8	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (257 aa)
	exoc2	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (922 aa)
	syngr3	Synaptogyrin. (230 aa)
	parp1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1015 aa)
	LOC101161879	Inhibitor of DNA binding 1, HLH protein. (159 aa)
	tsc1	TSC complex subunit 1b. (1198 aa)
	exoc4	Exocyst complex component 4. (983 aa)
	bivm	Basic, immunoglobulin-like variable motif containing. (506 aa)
	H2MN86_ORYLA	ADP-ribosylation factor 6b. (112 aa)
	fez1	Fasciculation and elongation protein zeta 1 (zygin I). (405 aa)
	hypk	Huntingtin interacting protein K. (121 aa)
	chmp6	Charged multivesicular body protein 6. (221 aa)
	Atm	Uncharacterized protein. (147 aa)
	ENSORLP00000027619	TAN domain-containing protein. (321 aa)
	LOC101158526	Rho family GTPase 2. (234 aa)
	exoc5	Exocyst complex component 5. (717 aa)
	alox5ap	Arachidonate 5-lipoxygenase-activating protein. (157 aa)
	ENSORLP00000031311	Uncharacterized protein. (248 aa)
	ercc2	Excision repair cross-complementation group 2. (761 aa)
	hax1	HCLS1 associated protein X-1. (282 aa)
	LOC101167464	Death-domain associated protein. (729 aa)
	gtf2h3	General transcription factor IIH, polypeptide 3. (326 aa)
	ENSORLP00000036355	Uncharacterized protein. (102 aa)
	nfe2	Nuclear factor, erythroid 2. (471 aa)
	LOC101170839	Mortality factor 4 like 1. (323 aa)
	LOC101163074	Si:ch211-25d12.7. (261 aa)
	mnat1	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
	pex14	Peroxisomal biogenesis factor 14. (374 aa)
	ercc6	Excision repair cross-complementation group 6. (1342 aa)
	LOC101167186	Methyl CpG binding protein 2. (1004 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Atm	ENSORLP00000027619	ENSORLP00000026266	ENSORLP00000027619	Uncharacterized protein.	TAN domain-containing protein.	0.929
Atm	LOC101167464	ENSORLP00000026266	ENSORLP00000033835	Uncharacterized protein.	Death-domain associated protein.	0.415
Atm	bivm	ENSORLP00000026266	ENSORLP00000019674	Uncharacterized protein.	Basic, immunoglobulin-like variable motif containing.	0.618
Atm	ercc2	ENSORLP00000026266	ENSORLP00000032234	Uncharacterized protein.	Excision repair cross-complementation group 2.	0.719
Atm	ercc4	ENSORLP00000026266	ENSORLP00000003684	Uncharacterized protein.	Excision repair cross-complementation group 4.	0.621
Atm	ercc5	ENSORLP00000026266	ENSORLP00000006287	Uncharacterized protein.	Excision repair cross-complementation group 5.	0.618
ENSORLP00000027619	Atm	ENSORLP00000027619	ENSORLP00000026266	TAN domain-containing protein.	Uncharacterized protein.	0.929
ENSORLP00000027619	LOC101167464	ENSORLP00000027619	ENSORLP00000033835	TAN domain-containing protein.	Death-domain associated protein.	0.415
ENSORLP00000027619	bivm	ENSORLP00000027619	ENSORLP00000019674	TAN domain-containing protein.	Basic, immunoglobulin-like variable motif containing.	0.618
ENSORLP00000027619	ercc2	ENSORLP00000027619	ENSORLP00000032234	TAN domain-containing protein.	Excision repair cross-complementation group 2.	0.719
ENSORLP00000027619	ercc4	ENSORLP00000027619	ENSORLP00000003684	TAN domain-containing protein.	Excision repair cross-complementation group 4.	0.621
ENSORLP00000027619	ercc5	ENSORLP00000027619	ENSORLP00000006287	TAN domain-containing protein.	Excision repair cross-complementation group 5.	0.618
ENSORLP00000031311	men1	ENSORLP00000031311	ENSORLP00000014617	Uncharacterized protein.	Multiple endocrine neoplasia I.	0.598
ENSORLP00000031311	tsc1	ENSORLP00000031311	ENSORLP00000018027	Uncharacterized protein.	TSC complex subunit 1b.	0.545
ENSORLP00000036355	men1	ENSORLP00000036355	ENSORLP00000014617	Uncharacterized protein.	Multiple endocrine neoplasia I.	0.485
H2MN86_ORYLA	exoc2	ENSORLP00000020187	ENSORLP00000015863	ADP-ribosylation factor 6b.	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.	0.590
H2MN86_ORYLA	exoc4	ENSORLP00000020187	ENSORLP00000018215	ADP-ribosylation factor 6b.	Exocyst complex component 4.	0.570
H2MN86_ORYLA	exoc5	ENSORLP00000020187	ENSORLP00000030639	ADP-ribosylation factor 6b.	Exocyst complex component 5.	0.746
H2MN86_ORYLA	stx5	ENSORLP00000020187	ENSORLP00000002800	ADP-ribosylation factor 6b.	Syntaxin 5A; Belongs to the syntaxin family.	0.541
LOC101155643	exoc2	ENSORLP00000005748	ENSORLP00000015863	Rho family GTPase 2.	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.	0.406