STRINGSTRING
mib1 mib1 hhex hhex LOC101157279 LOC101157279 vps52 vps52 LOC101155037 LOC101155037 wdr55 wdr55 yap1 yap1 VANGL2 VANGL2 LOC101156084 LOC101156084 tp73 tp73 hnf1b hnf1b LOC101156758 LOC101156758 LOC101165094 LOC101165094 nipbl nipbl LOC101167144 LOC101167144 rnpc3 rnpc3 LOC101156754 LOC101156754 H2LU88_ORYLA H2LU88_ORYLA nkx2-3 nkx2-3 msc msc sfrp2 sfrp2 Epg5 Epg5 invs invs sav1 sav1 ednr ednr shh shh LOC101172593 LOC101172593 H2M5I5_ORYLA H2M5I5_ORYLA LOC101158386 LOC101158386 LOC101171428 LOC101171428 hlx hlx ruvbl2 ruvbl2 chd8 chd8 foxf2 foxf2 prdm1b prdm1b LOC105357073 LOC105357073 fgfr2 fgfr2 clmp clmp foxl1 foxl1 me-t me-t smo smo id2 id2 tbx1 tbx1 LOC101157720 LOC101157720 tp63 tp63 prdm1 prdm1 myf5 myf5 ascl1 ascl1 tbx20 tbx20 bcl2 bcl2 LOC101168243 LOC101168243 gata4 gata4 gata6 gata6 LOC100049225 LOC100049225 prkci prkci LOC110014793 LOC110014793 il6st il6st utp25 utp25 pkd1 pkd1 pitx2 pitx2 ENSORLP00000025959 ENSORLP00000025959 nkx3-2 nkx3-2 hand2 hand2 med24 med24 mb mb klf5 klf5 ezh2 ezh2 ahi1 ahi1 tcf21 tcf21 foxa3 foxa3 LOC101168331 LOC101168331 IKZF5 IKZF5 MYOCD MYOCD LOC101166715 LOC101166715 pdgfc pdgfc gata5 gata5 ENSORLP00000035859 ENSORLP00000035859 LOC101160830 LOC101160830 rb1 rb1 NKX2-3 NKX2-3 ezh1 ezh1 pkdcc pkdcc pdx1 pdx1 wtip wtip agr2 agr2 LOC101161541 LOC101161541 myod1 myod1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mib1Mindbomb E3 ubiquitin protein ligase 1. (1081 aa)
hhexHomeobox domain-containing protein. (469 aa)
LOC101157279Uncharacterized protein. (619 aa)
vps52VPS52 subunit of GARP complex. (724 aa)
LOC101155037Transforming growth factor beta; Belongs to the TGF-beta family. (420 aa)
wdr55WD repeat-containing protein 55; Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis, including thymus development; Belongs to the WD repeat WDR55 family. (401 aa)
yap1Transcriptional coactivator YAP1; Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis (By similarity). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. (440 aa)
VANGL2Vang-like protein. (525 aa)
LOC101156084G protein-coupled receptor 22b. (438 aa)
tp73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (540 aa)
hnf1bHNF1 homeobox Ba. (555 aa)
LOC101156758Uncharacterized protein. (382 aa)
LOC101165094Cordon-bleu WH2 repeat protein. (1444 aa)
nipblNipped-B protein. (2335 aa)
LOC101167144IKAROS family zinc finger 5. (418 aa)
rnpc3RNA-binding region (RNP1, RRM) containing 3. (500 aa)
LOC101156754Nipped-B protein. (2658 aa)
H2LU88_ORYLANK3 homeobox 3. (137 aa)
nkx2-3NK2 homeobox 3. (341 aa)
mscMusculin (activated B-cell factor-1). (166 aa)
sfrp2Secreted frizzled-related protein 2. (290 aa)
Epg5Uncharacterized protein. (323 aa)
invsInversin. (963 aa)
sav1Salvador family WW domain containing protein 1. (391 aa)
ednrG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (413 aa)
shhHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (414 aa)
LOC101172593Tumor necrosis factor a (TNF superfamily, member 2). (279 aa)
H2M5I5_ORYLANK2 transcription factor related 7. (150 aa)
LOC101158386Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family. (419 aa)
LOC101171428FZ domain-containing protein. (337 aa)
hlxH2.0-like homeo box 1 (Drosophila). (387 aa)
ruvbl2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (459 aa)
chd8Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2553 aa)
foxf2Forkhead box F2. (383 aa)
prdm1bPrdm1b. (775 aa)
LOC105357073G_PROTEIN_RECEP_F1_2 domain-containing protein. (418 aa)
fgfr2Fibroblast growth factor receptor. (832 aa)
clmpUncharacterized protein. (384 aa)
foxl1Forkhead box L1. (326 aa)
me-tMe-Tam. (419 aa)
smoSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (828 aa)
id2Inhibitor of DNA binding 2a. (137 aa)
tbx1T-box transcription factor 1. (503 aa)
LOC101157720Kruppel-like factor 5 like. (424 aa)
tp63Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (683 aa)
prdm1Prdm1a. (845 aa)
myf5Myogenic factor. (240 aa)
ascl1Achaete-scute family bHLH transcription factor 1a. (178 aa)
tbx20T-box transcription factor 20. (439 aa)
bcl2BCL2 apoptosis regulator b. (202 aa)
LOC101168243Forkhead box F2a. (376 aa)
gata4GATA binding protein 4. (388 aa)
gata6GATA binding protein 6. (489 aa)
LOC100049225Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family. (427 aa)
prkciProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (554 aa)
LOC110014793Histone domain-containing protein. (149 aa)
il6stUncharacterized protein. (868 aa)
utp25UTP25 small subunit processor component. (750 aa)
pkd1Uncharacterized protein. (4114 aa)
pitx2Homeobox protein. (366 aa)
ENSORLP00000025959PR domain containing 1b, with ZNF domain. (606 aa)
nkx3-2NK3 homeobox 2. (263 aa)
hand2Heart and neural crest derivatives expressed 2. (232 aa)
med24Mediator complex subunit 24. (985 aa)
mbMyoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. (147 aa)
klf5Progesterone immunomodulatory binding factor 1. (498 aa)
ezh2Uncharacterized protein. (775 aa)
ahi1Abelson helper integration site 1. (854 aa)
tcf21Transcription factor 21. (171 aa)
foxa3Me-FKH1. (453 aa)
LOC101168331Uncharacterized protein. (312 aa)
IKZF5IKAROS family zinc finger 5. (411 aa)
MYOCDMyocardin. (884 aa)
LOC101166715Uncharacterized protein; Belongs to the potassium channel family. (719 aa)
pdgfcPlatelet derived growth factor c; Belongs to the PDGF/VEGF growth factor family. (342 aa)
gata5GATA binding protein 5. (364 aa)
ENSORLP00000035859Homeobox domain-containing protein. (188 aa)
LOC101160830Uncharacterized protein. (259 aa)
rb1Retinoblastoma 1. (916 aa)
NKX2-3NK2 homeobox 3. (351 aa)
ezh1Uncharacterized protein. (807 aa)
pkdccProtein kinase domain containing, cytoplasmic b. (473 aa)
pdx1Pancreatic and duodenal homeobox 1. (262 aa)
wtipWT1 interacting protein. (699 aa)
agr2Anterior gradient 2. (164 aa)
LOC101161541Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family. (695 aa)
myod1Myogenic factor. (297 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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