(20 nodes) Brain morphogenesis network (Oryzias latipes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	slc6a4	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (671 aa)
	mkks	McKusick-Kaufman syndrome. (564 aa)
	lamc1	Uncharacterized protein. (1595 aa)
	LOC101156825	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (579 aa)
	ctnna1	Catenin (cadherin-associated protein), alpha 1. (929 aa)
	bbs4	Bardet-Biedl syndrome 4. (535 aa)
	LOC101172571	FA complementation group D2. (1518 aa)
	uchl5	Ubiquitin carboxyl-terminal hydrolase. (329 aa)
	lamc3	Laminin, gamma 3. (1645 aa)
	znf335	Zinc finger protein 335. (1618 aa)
	fancc	FA complementation group C. (654 aa)
	foxh1	Forkhead box H1. (511 aa)
	ctnna2	Catenin (cadherin-associated protein), alpha 2. (905 aa)
	Nf1	Uncharacterized protein. (506 aa)
	bbs1	Bardet-Biedl syndrome 1. (583 aa)
	gsx2	GS homeobox 2. (238 aa)
	crppa	CDP-L-ribitol pyrophosphorylase A. (442 aa)
	H2MJT0_ORYLA	Uncharacterized protein. (589 aa)
	cyp26a1	Cytochrome P450 26A1; Belongs to the cytochrome P450 family. (488 aa)
	smo	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (828 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H2MJT0_ORYLA	Nf1	ENSORLP00000018929	ENSORLP00000026133	Uncharacterized protein.	Uncharacterized protein.	0.943
LOC101172571	fancc	ENSORLP00000042398	ENSORLP00000033538	FA complementation group D2.	FA complementation group C.	0.998
Nf1	H2MJT0_ORYLA	ENSORLP00000026133	ENSORLP00000018929	Uncharacterized protein.	Uncharacterized protein.	0.943
bbs1	bbs4	ENSORLP00000025258	ENSORLP00000002011	Bardet-Biedl syndrome 1.	Bardet-Biedl syndrome 4.	0.988
bbs1	mkks	ENSORLP00000025258	ENSORLP00000015280	Bardet-Biedl syndrome 1.	McKusick-Kaufman syndrome.	0.434
bbs1	smo	ENSORLP00000025258	ENSORLP00000018001	Bardet-Biedl syndrome 1.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.807
bbs4	bbs1	ENSORLP00000002011	ENSORLP00000025258	Bardet-Biedl syndrome 4.	Bardet-Biedl syndrome 1.	0.988
bbs4	smo	ENSORLP00000002011	ENSORLP00000018001	Bardet-Biedl syndrome 4.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.682
ctnna1	ctnna2	ENSORLP00000009022	ENSORLP00000029237	Catenin (cadherin-associated protein), alpha 1.	Catenin (cadherin-associated protein), alpha 2.	0.901
ctnna2	ctnna1	ENSORLP00000029237	ENSORLP00000009022	Catenin (cadherin-associated protein), alpha 2.	Catenin (cadherin-associated protein), alpha 1.	0.901
fancc	LOC101172571	ENSORLP00000033538	ENSORLP00000042398	FA complementation group C.	FA complementation group D2.	0.998
mkks	bbs1	ENSORLP00000015280	ENSORLP00000025258	McKusick-Kaufman syndrome.	Bardet-Biedl syndrome 1.	0.434
smo	bbs1	ENSORLP00000018001	ENSORLP00000025258	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	Bardet-Biedl syndrome 1.	0.807
smo	bbs4	ENSORLP00000018001	ENSORLP00000002011	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	Bardet-Biedl syndrome 4.	0.682