(13 nodes) Regulation of nitric-oxide synthase activity network (Oryzias latipes)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	LOC101161367	GTP cyclohydrolase 2. (236 aa)
	cav3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
	dhfr	Dihydrofolate reductase. (189 aa)
	htr2b	5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled. (473 aa)
	LOC101161673	Apolipoprotein Eb. (265 aa)
	npr3	ANF_receptor domain-containing protein. (480 aa)
	scarb1	Scavenger receptor class B, member 1; Belongs to the CD36 family. (532 aa)
	LOC101169209	Uncharacterized protein. (283 aa)
	LOC101168423	GTP cyclohydrolase 1. (257 aa)
	s100a1	Protein S100; Belongs to the S-100 family. (99 aa)
	lepa	Leptin-A; May function as part of a signaling pathway that acts to regulate the size of the body fat depot. (185 aa)
	LOC101166399	Apolipoprotein Ea. (262 aa)
	ENSORLP00000045591	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (130 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSORLP00000045591	cav3	ENSORLP00000045591	ENSORLP00000000896	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.555
LOC101161367	dhfr	ENSORLP00000023428	ENSORLP00000006371	GTP cyclohydrolase 2.	Dihydrofolate reductase.	0.471
LOC101161673	LOC101166399	ENSORLP00000017533	ENSORLP00000045105	Apolipoprotein Eb.	Apolipoprotein Ea.	0.566
LOC101161673	LOC101169209	ENSORLP00000017533	ENSORLP00000036862	Apolipoprotein Eb.	Uncharacterized protein.	0.503
LOC101161673	scarb1	ENSORLP00000017533	ENSORLP00000028225	Apolipoprotein Eb.	Scavenger receptor class B, member 1; Belongs to the CD36 family.	0.644
LOC101166399	LOC101161673	ENSORLP00000045105	ENSORLP00000017533	Apolipoprotein Ea.	Apolipoprotein Eb.	0.566
LOC101168423	dhfr	ENSORLP00000038392	ENSORLP00000006371	GTP cyclohydrolase 1.	Dihydrofolate reductase.	0.471
LOC101169209	LOC101161673	ENSORLP00000036862	ENSORLP00000017533	Uncharacterized protein.	Apolipoprotein Eb.	0.503
LOC101169209	lepa	ENSORLP00000036862	ENSORLP00000045049	Uncharacterized protein.	Leptin-A; May function as part of a signaling pathway that acts to regulate the size of the body fat depot.	0.558
cav3	ENSORLP00000045591	ENSORLP00000000896	ENSORLP00000045591	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.555
cav3	scarb1	ENSORLP00000000896	ENSORLP00000028225	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Scavenger receptor class B, member 1; Belongs to the CD36 family.	0.484
dhfr	LOC101161367	ENSORLP00000006371	ENSORLP00000023428	Dihydrofolate reductase.	GTP cyclohydrolase 2.	0.471
dhfr	LOC101168423	ENSORLP00000006371	ENSORLP00000038392	Dihydrofolate reductase.	GTP cyclohydrolase 1.	0.471
lepa	LOC101169209	ENSORLP00000045049	ENSORLP00000036862	Leptin-A; May function as part of a signaling pathway that acts to regulate the size of the body fat depot.	Uncharacterized protein.	0.558
scarb1	LOC101161673	ENSORLP00000028225	ENSORLP00000017533	Scavenger receptor class B, member 1; Belongs to the CD36 family.	Apolipoprotein Eb.	0.644
scarb1	cav3	ENSORLP00000028225	ENSORLP00000000896	Scavenger receptor class B, member 1; Belongs to the CD36 family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.484