(38 nodes) Protein kinase A binding network (Oryzias latipes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	gsk3b	Glycogen synthase kinase 3 beta, genome duplicate a. (216 aa)
	arfgef2	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited). (1836 aa)
	LOC101159349	Protein kinase, cAMP-dependent, regulatory, type II, alpha A. (391 aa)
	prkar1a	Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) b. (380 aa)
	prkar2b	Protein kinase cAMP-dependent type II regulatory subunit beta. (409 aa)
	LOC101160681	WH2 domain-containing protein. (450 aa)
	LOC101168720	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (438 aa)
	prkar1b	Protein kinase, cAMP-dependent, regulatory, type I, beta. (380 aa)
	LOC101165595	Zgc:109889. (553 aa)
	wasf3	WASP family member 3b. (486 aa)
	dact1	Dishevelled binding antagonist of beta catenin 1. (870 aa)
	akap10	A kinase (PRKA) anchor protein 10. (608 aa)
	wasf2	WASP family member 2. (471 aa)
	H2M7Z9_ORYLA	Uncharacterized protein. (494 aa)
	acbd3	Acyl-Coenzyme A binding domain containing 3. (546 aa)
	H2MJK6_ORYLA	Uncharacterized protein. (91 aa)
	Akap1	KH domain-containing protein. (231 aa)
	akap17a	A kinase (PRKA) anchor protein 17A. (648 aa)
	gskip	Gsk3b interacting protein. (173 aa)
	LOC101164255	Si:ch211-106h4.9. (1145 aa)
	H2MW65_ORYLA	Protein kinase, cAMP-dependent, regulatory, type II, alpha, B. (232 aa)
	lrrk2	Leucine-rich repeat kinase 2. (2241 aa)
	akap7	Uncharacterized protein. (501 aa)
	prrc1	Proline-rich coiled-coil 1. (420 aa)
	sphkap	SPHK1 interactor, AKAP domain containing. (1540 aa)
	ENSORLP00000030873	PALM2-AKAP2 fusion. (722 aa)
	ENSORLP00000031239	Si:dkeyp-81f3.4. (168 aa)
	LOC101166715	Uncharacterized protein; Belongs to the potassium channel family. (719 aa)
	dact2	Dishevelled-binding antagonist of beta-catenin 2. (821 aa)
	akap12	A kinase (PRKA) anchor protein 12b. (1419 aa)
	arfgef1	ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited). (1920 aa)
	dact3	Uncharacterized protein. (640 aa)
	akap6	A kinase (PRKA) anchor protein 6. (2292 aa)
	LOC110016650	Speriolin_C domain-containing protein. (298 aa)
	wasf1	WASP family member 1. (583 aa)
	LOC101156518	Uncharacterized protein. (636 aa)
	LOC101161541	Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family. (695 aa)
	LOC101160344	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily. (480 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Akap1	ENSORLP00000031239	ENSORLP00000018953	ENSORLP00000031239	KH domain-containing protein.	Si:dkeyp-81f3.4.	0.400
Akap1	H2MW65_ORYLA	ENSORLP00000018953	ENSORLP00000023083	KH domain-containing protein.	Protein kinase, cAMP-dependent, regulatory, type II, alpha, B.	0.695
Akap1	LOC101159349	ENSORLP00000018953	ENSORLP00000003822	KH domain-containing protein.	Protein kinase, cAMP-dependent, regulatory, type II, alpha A.	0.695
Akap1	akap10	ENSORLP00000018953	ENSORLP00000013676	KH domain-containing protein.	A kinase (PRKA) anchor protein 10.	0.501
Akap1	akap12	ENSORLP00000018953	ENSORLP00000037744	KH domain-containing protein.	A kinase (PRKA) anchor protein 12b.	0.559
Akap1	akap6	ENSORLP00000018953	ENSORLP00000039971	KH domain-containing protein.	A kinase (PRKA) anchor protein 6.	0.560
Akap1	akap7	ENSORLP00000018953	ENSORLP00000026749	KH domain-containing protein.	Uncharacterized protein.	0.560
Akap1	prkar1a	ENSORLP00000018953	ENSORLP00000004817	KH domain-containing protein.	Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) b.	0.695
Akap1	prkar1b	ENSORLP00000018953	ENSORLP00000010584	KH domain-containing protein.	Protein kinase, cAMP-dependent, regulatory, type I, beta.	0.695
Akap1	prkar2b	ENSORLP00000018953	ENSORLP00000005487	KH domain-containing protein.	Protein kinase cAMP-dependent type II regulatory subunit beta.	0.695
ENSORLP00000030873	H2M7Z9_ORYLA	ENSORLP00000030873	ENSORLP00000014610	PALM2-AKAP2 fusion.	Uncharacterized protein.	0.899
ENSORLP00000031239	Akap1	ENSORLP00000031239	ENSORLP00000018953	Si:dkeyp-81f3.4.	KH domain-containing protein.	0.400
ENSORLP00000031239	H2MW65_ORYLA	ENSORLP00000031239	ENSORLP00000023083	Si:dkeyp-81f3.4.	Protein kinase, cAMP-dependent, regulatory, type II, alpha, B.	0.678
ENSORLP00000031239	LOC101159349	ENSORLP00000031239	ENSORLP00000003822	Si:dkeyp-81f3.4.	Protein kinase, cAMP-dependent, regulatory, type II, alpha A.	0.678
ENSORLP00000031239	prkar1a	ENSORLP00000031239	ENSORLP00000004817	Si:dkeyp-81f3.4.	Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) b.	0.678
ENSORLP00000031239	prkar1b	ENSORLP00000031239	ENSORLP00000010584	Si:dkeyp-81f3.4.	Protein kinase, cAMP-dependent, regulatory, type I, beta.	0.678
ENSORLP00000031239	prkar2b	ENSORLP00000031239	ENSORLP00000005487	Si:dkeyp-81f3.4.	Protein kinase cAMP-dependent type II regulatory subunit beta.	0.678
H2M7Z9_ORYLA	ENSORLP00000030873	ENSORLP00000014610	ENSORLP00000030873	Uncharacterized protein.	PALM2-AKAP2 fusion.	0.899
H2MW65_ORYLA	Akap1	ENSORLP00000023083	ENSORLP00000018953	Protein kinase, cAMP-dependent, regulatory, type II, alpha, B.	KH domain-containing protein.	0.695
H2MW65_ORYLA	ENSORLP00000031239	ENSORLP00000023083	ENSORLP00000031239	Protein kinase, cAMP-dependent, regulatory, type II, alpha, B.	Si:dkeyp-81f3.4.	0.678