STRINGSTRING
TGFBR2 TGFBR2 slc10a7 slc10a7 LOC101171247 LOC101171247 WNT7A WNT7A sema3d sema3d FGF6-2 FGF6-2 smpd3 smpd3 LOC105357487 LOC105357487 cyp26b1 cyp26b1 itgb8 itgb8 dlx3 dlx3 dlx5 dlx5 LOC100301625 LOC100301625 H2LKM3_ORYLA H2LKM3_ORYLA LOC101167529 LOC101167529 bmp6 bmp6 sox6b sox6b anxa6 anxa6 H2LSA7_ORYLA H2LSA7_ORYLA LOC101163987 LOC101163987 LOC101156305 LOC101156305 sfrp2 sfrp2 LOC101160069 LOC101160069 edn1 edn1 LOC101172843 LOC101172843 bmp2 bmp2 bmp5 bmp5 runx2 runx2 LOC101162457 LOC101162457 ccn1 ccn1 LOC101155025 LOC101155025 LOC101170723 LOC101170723 cnmd cnmd LOC101171428 LOC101171428 Wnt7a Wnt7a LOC101173146 LOC101173146 mkks mkks uxs1 uxs1 foxc1 foxc1 srf srf bmp4 bmp4 LOC101162832 LOC101162832 serpinh1 serpinh1 zmpste24 zmpste24 tbx1 tbx1 HAND1 HAND1 FGF6 FGF6 smarcal1 smarcal1 evc evc CYTL1 CYTL1 msx1 msx1 cdh2 cdh2 dlx2 dlx2 snai2 snai2 LOC101172864 LOC101172864 LOC101160370 LOC101160370 LOC101170824 LOC101170824 pkd1 pkd1 sec23a sec23a bbs1 bbs1 ift80 ift80 tsku tsku MEF2D MEF2D gnptab gnptab il-17a/f-1 il-17a/f-1 bmpr1b bmpr1b ext2 ext2 OTOR OTOR LOC105358811 LOC105358811 LOC101174373 LOC101174373 LOC101170808 LOC101170808 trip11 trip11 LOC101167660 LOC101167660 wnt5b wnt5b sox5 sox5 LOC101173202 LOC101173202 ENSORLP00000035411 ENSORLP00000035411 creb3l2 creb3l2 sulf1 sulf1 snx19 snx19 LOC101160830 LOC101160830 rb1 rb1 barx1 barx1 LOC101156556 LOC101156556 eif2ak3 eif2ak3 fgf18 fgf18 LOC101169470 LOC101169470 LOC111949083 LOC111949083 mgp mgp LOC101155422 LOC101155422 CCN3 CCN3 dlx1 dlx1 LOC101163346 LOC101163346 LOC101171739 LOC101171739 LOC101169384 LOC101169384 il-17a/f-3 il-17a/f-3 LOC101155279 LOC101155279 fgf8 fgf8 bmpr2 bmpr2 yap1 yap1 DDRGK1 DDRGK1 LOC101157631 LOC101157631 sox6a sox6a Nog Nog fgf3 fgf3 H2L3P1_ORYLA H2L3P1_ORYLA fgf4 fgf4 LOC101158262 LOC101158262
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (540 aa)
slc10a7Sodium/bile acid cotransporter; Does not show transport activity towards bile acids or steroid sulfates; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. (378 aa)
LOC101171247RAP1A, member of RAS oncogene family a. (202 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
sema3dSema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D; Belongs to the semaphorin family. (792 aa)
FGF6-2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
smpd3Sphingomyelin phosphodiesterase 3, neutral. (716 aa)
LOC105357487Activin_recp domain-containing protein. (762 aa)
cyp26b1Cytochrome P450 26B1; Belongs to the cytochrome P450 family. (512 aa)
itgb8Integrin beta; Belongs to the integrin beta chain family. (745 aa)
dlx3Distal-less homeobox 3b. (278 aa)
dlx5Distal-less homeobox 5a. (296 aa)
LOC100301625Forkhead box Q2. (281 aa)
H2LKM3_ORYLAIg-like domain-containing protein. (246 aa)
LOC101167529RAP1A, member of RAS oncogene family b. (185 aa)
bmp6Bone morphogenetic protein 6. (424 aa)
sox6bSRY-box containing gene 6b. (804 aa)
anxa6Annexin. (699 aa)
H2LSA7_ORYLANoggin; Belongs to the noggin family. (215 aa)
LOC101163987Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (530 aa)
LOC101156305Transmembrane anterior posterior transformation 1b. (643 aa)
sfrp2Secreted frizzled-related protein 2. (290 aa)
LOC101160069Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (448 aa)
edn1Endothelin 1. (220 aa)
LOC101172843Uncharacterized protein. (543 aa)
bmp2TGF_BETA_2 domain-containing protein. (413 aa)
bmp5Bone morphogenetic protein 5. (417 aa)
runx2Runt-related transcription factor. (461 aa)
LOC101162457RNA polymerase I and III subunit D. (153 aa)
ccn1Cellular communication network factor 1. (376 aa)
LOC101155025Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
LOC101170723Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (369 aa)
cnmdChondromodulin-I. (316 aa)
LOC101171428FZ domain-containing protein. (337 aa)
Wnt7aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (329 aa)
LOC101173146Bone morphogenetic protein 7b. (427 aa)
mkksMcKusick-Kaufman syndrome. (564 aa)
uxs1UDP-glucuronate decarboxylase 1. (418 aa)
foxc1Forkhead box C1a. (465 aa)
srfSerum response factor b. (611 aa)
bmp4Bone morphogenetic protein 4. (441 aa)
LOC101162832Extracellular sulfatase. (885 aa)
serpinh1Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b; Belongs to the serpin family. (445 aa)
zmpste24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (467 aa)
tbx1T-box transcription factor 1. (503 aa)
HAND1Heart and neural crest derivatives expressed 1. (191 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (198 aa)
smarcal1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (893 aa)
evcUncharacterized protein. (984 aa)
CYTL1Cytokine like 1. (173 aa)
msx1Muscle segment homeobox 1a. (275 aa)
cdh2Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (908 aa)
dlx2Homeobox domain-containing protein. (277 aa)
snai2Snail family zinc finger 2. (260 aa)
LOC101172864Uncharacterized protein. (255 aa)
LOC101160370Runt-related transcription factor. (417 aa)
LOC101170824Uncharacterized protein. (867 aa)
pkd1Uncharacterized protein. (4114 aa)
sec23aProtein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (611 aa)
bbs1Bardet-Biedl syndrome 1. (583 aa)
ift80Intraflagellar transport 80 homolog (Chlamydomonas). (786 aa)
tskuTsukushi small leucine rich proteoglycan homolog (Xenopus laevis). (352 aa)
MEF2DMyocyte enhancer factor 2D. (562 aa)
gnptabN-acetylglucosamine-1-phosphate transferase subunits alpha and beta. (1234 aa)
il-17a/f-1Interleukin-17A/F-1. (152 aa)
bmpr1bSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
ext2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (719 aa)
OTOROtoraplin. (129 aa)
LOC105358811MADS-box domain-containing protein. (552 aa)
LOC101174373Myocyte enhancer factor 2d. (614 aa)
LOC101170808Epiphycan. (322 aa)
trip11Thyroid hormone receptor interactor 11. (1959 aa)
LOC101167660Chondromodulin. (327 aa)
wnt5bProtein Wnt-5b; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity). (436 aa)
sox5HMG box domain-containing protein. (880 aa)
LOC101173202RUNX family transcription factor 1. (574 aa)
ENSORLP00000035411Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (114 aa)
creb3l2cAMP responsive element binding protein 3-like 2. (544 aa)
sulf1Sulfatase 1. (1151 aa)
snx19Sorting nexin 19b. (950 aa)
LOC101160830Uncharacterized protein. (259 aa)
rb1Retinoblastoma 1. (916 aa)
barx1BARX homeobox 1. (240 aa)
LOC101156556Transmembrane anterior posterior transformation 1a. (602 aa)
eif2ak3Protein kinase domain-containing protein. (1094 aa)
fgf18Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
LOC101169470Activated leukocyte cell adhesion molecule b. (592 aa)
LOC111949083Forkhead box C1. (471 aa)
mgpGla domain-containing protein. (122 aa)
LOC101155422Uncharacterized protein. (115 aa)
CCN3Cellular communication network factor 3. (366 aa)
dlx1Distal-less homeobox 1a. (253 aa)
LOC101163346Bone morphogenetic protein 16. (516 aa)
LOC101171739Si:dkey-49n23.1; Belongs to the semaphorin family. (808 aa)
LOC101169384Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (523 aa)
il-17a/f-3Interleukin-17A/F-3. (157 aa)
LOC101155279AT rich interactive domain 5A (MRF1-like). (565 aa)
fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1056 aa)
yap1Transcriptional coactivator YAP1; Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis (By similarity). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. (440 aa)
DDRGK1DDRGK domain containing 1. (290 aa)
LOC101157631Transforming growth factor beta; Belongs to the TGF-beta family. (444 aa)
sox6aHMG box domain-containing protein. (814 aa)
NogNoggin; Belongs to the noggin family. (229 aa)
fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (245 aa)
H2L3P1_ORYLAExtracellular matrix protein 1a. (122 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (188 aa)
LOC101158262Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (921 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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