(43 nodes) Regulation of stress fiber assembly network (Oryzias latipes)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	nrp1	Neuropilin; Belongs to the neuropilin family. (938 aa)
	LOC101157330	Synaptopodin 2-like b. (1189 aa)
	LOC105355609	F11 receptor, tandem duplicate 1. (298 aa)
	lpar1	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (352 aa)
	pak2	Non-specific serine/threonine protein kinase. (532 aa)
	LOC101169804	Epithelial cell adhesion molecule. (386 aa)
	nf2	Neurofibromin 2a (merlin). (610 aa)
	LOC101169001	Rho GTPase activating protein 6. (732 aa)
	LOC101169249	Non-specific serine/threonine protein kinase. (514 aa)
	ENSORLP00000031311	Uncharacterized protein. (248 aa)
	LOC101162133	Prostaglandin E receptor 4 (subtype EP4) a; Belongs to the G-protein coupled receptor 1 family. (471 aa)
	frmd7	FERM domain-containing protein. (764 aa)
	LOC111948201	Stathmin; Belongs to the stathmin family. (163 aa)
	limch1	LIM and calponin homology domains 1b. (1051 aa)
	ppm1f	Protein phosphatase, Mg2+/Mn2+ dependent, 1F. (432 aa)
	tgfb3	Transforming growth factor beta; Belongs to the TGF-beta family. (405 aa)
	ttc8	Tetratricopeptide repeat domain 8. (505 aa)
	LOC101169721	Apolipoprotein A-Ib. (323 aa)
	LOC101158525	Rap guanine nucleotide exchange factor (GEF) 3. (798 aa)
	itgb1bp1	Integrin beta 1 binding protein 1. (198 aa)
	rhpn2	Rhophilin, Rho GTPase binding protein 2. (686 aa)
	LOC101169401	ArfGAP with SH3 domain, ankyrin repeat and PH domain 3. (1014 aa)
	tsc1	TSC complex subunit 1b. (1198 aa)
	ppm1e	Protein phosphatase, Mg2+/Mn2+ dependent, 1E. (616 aa)
	rgcc	Regulator of cell cycle. (154 aa)
	rhpn1	Rhophilin, Rho GTPase binding protein 1. (684 aa)
	wnt11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
	bag4	BCL2 associated athanogene 4. (385 aa)
	mkks	McKusick-Kaufman syndrome. (564 aa)
	LOC101155815	Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
	LOC101162072	Prostaglandin E receptor 4 (subtype EP4) c; Belongs to the G-protein coupled receptor 1 family. (478 aa)
	cgnl1	Cingulin-like 1. (1300 aa)
	LOC101155575	Uncharacterized protein. (1806 aa)
	tesk1	Si:dkeyp-75h12.2. (680 aa)
	serpinf2	SERPIN domain-containing protein; Belongs to the serpin family. (476 aa)
	ptger4	G_PROTEIN_RECEP_F1_2 domain-containing protein. (443 aa)
	LOC101162621	Neurofibromin 2b (merlin). (604 aa)
	LOC101168985	Testis associated actin remodelling kinase 2. (490 aa)
	bbs4	Bardet-Biedl syndrome 4. (535 aa)
	LOC101155699	Protein S100; Belongs to the S-100 family. (96 aa)
	Mtor	Serine/threonine-protein kinase TOR. (1023 aa)
	H2L4B7_ORYLA	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (737 aa)
	LOC101158994	Protein kinase domain-containing protein. (670 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSORLP00000031311	H2L4B7_ORYLA	ENSORLP00000031311	ENSORLP00000000606	Uncharacterized protein.	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	0.850
ENSORLP00000031311	Mtor	ENSORLP00000031311	ENSORLP00000000608	Uncharacterized protein.	Serine/threonine-protein kinase TOR.	0.850
ENSORLP00000031311	bbs4	ENSORLP00000031311	ENSORLP00000002011	Uncharacterized protein.	Bardet-Biedl syndrome 4.	0.408
ENSORLP00000031311	mkks	ENSORLP00000031311	ENSORLP00000015280	Uncharacterized protein.	McKusick-Kaufman syndrome.	0.581
ENSORLP00000031311	nrp1	ENSORLP00000031311	ENSORLP00000042087	Uncharacterized protein.	Neuropilin; Belongs to the neuropilin family.	0.407
ENSORLP00000031311	tsc1	ENSORLP00000031311	ENSORLP00000018027	Uncharacterized protein.	TSC complex subunit 1b.	0.545
ENSORLP00000031311	ttc8	ENSORLP00000031311	ENSORLP00000020588	Uncharacterized protein.	Tetratricopeptide repeat domain 8.	0.408
H2L4B7_ORYLA	ENSORLP00000031311	ENSORLP00000000606	ENSORLP00000031311	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.850
H2L4B7_ORYLA	Mtor	ENSORLP00000000606	ENSORLP00000000608	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	Serine/threonine-protein kinase TOR.	0.968
H2L4B7_ORYLA	tsc1	ENSORLP00000000606	ENSORLP00000018027	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	TSC complex subunit 1b.	0.850
LOC101155815	tgfb3	ENSORLP00000011426	ENSORLP00000020737	Transforming growth factor beta; Belongs to the TGF-beta family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.901
LOC101162621	LOC101169249	ENSORLP00000003763	ENSORLP00000035392	Neurofibromin 2b (merlin).	Non-specific serine/threonine protein kinase.	0.540
LOC101162621	pak2	ENSORLP00000003763	ENSORLP00000039536	Neurofibromin 2b (merlin).	Non-specific serine/threonine protein kinase.	0.540
LOC101169249	LOC101162621	ENSORLP00000035392	ENSORLP00000003763	Non-specific serine/threonine protein kinase.	Neurofibromin 2b (merlin).	0.540
LOC101169249	nf2	ENSORLP00000035392	ENSORLP00000037017	Non-specific serine/threonine protein kinase.	Neurofibromin 2a (merlin).	0.540
LOC101169249	pak2	ENSORLP00000035392	ENSORLP00000039536	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase.	0.900
Mtor	ENSORLP00000031311	ENSORLP00000000608	ENSORLP00000031311	Serine/threonine-protein kinase TOR.	Uncharacterized protein.	0.850
Mtor	H2L4B7_ORYLA	ENSORLP00000000608	ENSORLP00000000606	Serine/threonine-protein kinase TOR.	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	0.968
Mtor	tsc1	ENSORLP00000000608	ENSORLP00000018027	Serine/threonine-protein kinase TOR.	TSC complex subunit 1b.	0.850
bbs4	ENSORLP00000031311	ENSORLP00000002011	ENSORLP00000031311	Bardet-Biedl syndrome 4.	Uncharacterized protein.	0.408