(26 nodes) Cardiac muscle cell development network (Oryzias latipes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cyp26a1	Cytochrome P450 26A1; Belongs to the cytochrome P450 family. (488 aa)
	sgcb	Sarcoglycan, beta (dystrophin-associated glycoprotein). (312 aa)
	H2L4B7_ORYLA	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (737 aa)
	Mtor	Serine/threonine-protein kinase TOR. (1023 aa)
	csrp3	Cysteine and glycine-rich protein 3 (cardiac LIM protein). (193 aa)
	LOC101159505	Titin-cap (telethonin). (179 aa)
	adprhl1	ADP-ribosylhydrolase like 1. (1026 aa)
	alpk2	Uncharacterized protein. (1429 aa)
	LRRC10B	Leucine rich repeat containing 10B. (405 aa)
	nkx2-5	Homeobox domain-containing protein. (319 aa)
	H2M122_ORYLA	Uncharacterized protein. (1268 aa)
	bmp2	TGF_BETA_2 domain-containing protein. (413 aa)
	alpk3	Uncharacterized protein. (1586 aa)
	srf	Serum response factor b. (611 aa)
	zmpste24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (467 aa)
	atg5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	lrrc10	Leucine rich repeat containing 10. (275 aa)
	LOC101169259	Ankyrin repeat and SOCS box containing 2a, tandem duplicate 1. (639 aa)
	map2k4	Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (428 aa)
	LOC105358811	MADS-box domain-containing protein. (552 aa)
	opa1	OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1034 aa)
	LOC101157940	Uncharacterized protein. (1846 aa)
	LOC101157753	Ankyrin repeat and SOCS box containing 2b. (581 aa)
	LOC101161098	Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily. (463 aa)
	maml1	Mastermind-like transcriptional coactivator 1. (989 aa)
	ENSORLP00000038844	Uncharacterized protein. (138 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSORLP00000038844	H2M122_ORYLA	ENSORLP00000038844	ENSORLP00000012102	Uncharacterized protein.	Uncharacterized protein.	0.917
ENSORLP00000038844	LOC101159505	ENSORLP00000038844	ENSORLP00000004223	Uncharacterized protein.	Titin-cap (telethonin).	0.491
H2L4B7_ORYLA	Mtor	ENSORLP00000000606	ENSORLP00000000608	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	Serine/threonine-protein kinase TOR.	0.968
H2L4B7_ORYLA	atg5	ENSORLP00000000606	ENSORLP00000019636	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.459
H2M122_ORYLA	ENSORLP00000038844	ENSORLP00000012102	ENSORLP00000038844	Uncharacterized protein.	Uncharacterized protein.	0.917
H2M122_ORYLA	LOC101159505	ENSORLP00000012102	ENSORLP00000004223	Uncharacterized protein.	Titin-cap (telethonin).	0.534
H2M122_ORYLA	csrp3	ENSORLP00000012102	ENSORLP00000000955	Uncharacterized protein.	Cysteine and glycine-rich protein 3 (cardiac LIM protein).	0.405
LOC101159505	ENSORLP00000038844	ENSORLP00000004223	ENSORLP00000038844	Titin-cap (telethonin).	Uncharacterized protein.	0.491
LOC101159505	H2M122_ORYLA	ENSORLP00000004223	ENSORLP00000012102	Titin-cap (telethonin).	Uncharacterized protein.	0.534
LOC101159505	csrp3	ENSORLP00000004223	ENSORLP00000000955	Titin-cap (telethonin).	Cysteine and glycine-rich protein 3 (cardiac LIM protein).	0.695
LOC101161098	map2k4	ENSORLP00000037389	ENSORLP00000029769	Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.	0.901
LOC105358811	nkx2-5	ENSORLP00000031967	ENSORLP00000009208	MADS-box domain-containing protein.	Homeobox domain-containing protein.	0.518
LOC105358811	srf	ENSORLP00000031967	ENSORLP00000016334	MADS-box domain-containing protein.	Serum response factor b.	0.905
Mtor	H2L4B7_ORYLA	ENSORLP00000000608	ENSORLP00000000606	Serine/threonine-protein kinase TOR.	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	0.968
Mtor	atg5	ENSORLP00000000608	ENSORLP00000019636	Serine/threonine-protein kinase TOR.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.459
atg5	H2L4B7_ORYLA	ENSORLP00000019636	ENSORLP00000000606	Autophagy protein 5; Involved in autophagic vesicle formation.	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	0.459
atg5	Mtor	ENSORLP00000019636	ENSORLP00000000608	Autophagy protein 5; Involved in autophagic vesicle formation.	Serine/threonine-protein kinase TOR.	0.459
atg5	opa1	ENSORLP00000019636	ENSORLP00000032749	Autophagy protein 5; Involved in autophagic vesicle formation.	OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.478
csrp3	H2M122_ORYLA	ENSORLP00000000955	ENSORLP00000012102	Cysteine and glycine-rich protein 3 (cardiac LIM protein).	Uncharacterized protein.	0.405
csrp3	LOC101159505	ENSORLP00000000955	ENSORLP00000004223	Cysteine and glycine-rich protein 3 (cardiac LIM protein).	Titin-cap (telethonin).	0.695