(48 nodes) Convergent extension network (Oryzias latipes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101159857	Angiomotin like 2b. (688 aa)
	ofd1	OFD1 centriole and centriolar satellite protein. (1078 aa)
	LOC101167011	Tyrosine-protein kinase. (526 aa)
	lrrc6	Leucine rich repeat containing 6. (504 aa)
	ENSORLP00000036098	Dynein assembly factor 1, axonemal. (317 aa)
	def6	DEF6 guanine nucleotide exchange factor a. (619 aa)
	wnt5b	Protein Wnt-5b; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity). (436 aa)
	ctnnb1	Catenin (cadherin-associated protein), beta 1. (783 aa)
	ppp1r12a	Protein phosphatase 1, regulatory subunit 12A. (1174 aa)
	LOC101160003	Mothers against decapentaplegic homolog. (464 aa)
	tab2	TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (733 aa)
	LOC101157019	Tyrosine-protein kinase. (537 aa)
	adgra3	Adhesion G protein-coupled receptor A3; Belongs to the G-protein coupled receptor 2 family. (1350 aa)
	PTK7	Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1072 aa)
	mcub	MCU domain-containing protein. (337 aa)
	LOC101162321	Tyrosine-protein kinase. (547 aa)
	LOC101172864	Uncharacterized protein. (255 aa)
	cdh2	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (908 aa)
	amotl2	Angiomotin like 2a. (697 aa)
	KLHL12	BTB domain-containing protein. (598 aa)
	LOC101162828	Mesoderm posterior ba. (262 aa)
	H2MGX0_ORYLA	Transmembrane protein 237a. (201 aa)
	me-t	Me-Tam. (419 aa)
	tdp2	Tyrosyl-DNA phosphodiesterase 2b. (359 aa)
	H2MA54_ORYLA	Uncharacterized protein. (489 aa)
	TMEM216	Transmembrane protein 216. (143 aa)
	Mcu	Mitochondrial calcium uniporter. (331 aa)
	YES1	Tyrosine-protein kinase. (550 aa)
	LOC101171428	FZ domain-containing protein. (337 aa)
	gdf3	Growth differentiation factor 3. (376 aa)
	nphp3	Nephronophthisis 3. (1220 aa)
	lrrc1	Leucine rich repeat containing 1. (497 aa)
	bmp2	TGF_BETA_2 domain-containing protein. (413 aa)
	chrd	Chordin; Belongs to the chordin family. (946 aa)
	LOC101160069	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (448 aa)
	invs	Inversin. (963 aa)
	sfrp2	Secreted frizzled-related protein 2. (290 aa)
	LOC101168365	Protein phosphatase 1 regulatory subunit. (908 aa)
	LOC101167529	RAP1A, member of RAS oncogene family b. (185 aa)
	LOC101168447	BTB domain-containing protein. (514 aa)
	desi2	Desumoylating isopeptidase 2. (212 aa)
	VANGL2	Vang-like protein. (525 aa)
	LOC101160267	Mitochondrial calcium uniporter dominant negative beta subunit. (317 aa)
	fibp	Fibroblast growth factor (acidic) intracellular binding protein a. (357 aa)
	LOC101163233	Uncharacterized protein. (626 aa)
	LOC101158262	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (921 aa)
	LOC101166111	Transmembrane protein 237b. (404 aa)
	LOC101171247	RAP1A, member of RAS oncogene family a. (202 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSORLP00000036098	lrrc6	ENSORLP00000036098	ENSORLP00000041179	Dynein assembly factor 1, axonemal.	Leucine rich repeat containing 6.	0.604
H2MA54_ORYLA	LOC101167529	ENSORLP00000015402	ENSORLP00000007312	Uncharacterized protein.	RAP1A, member of RAS oncogene family b.	0.410
H2MA54_ORYLA	LOC101171247	ENSORLP00000015402	ENSORLP00000042612	Uncharacterized protein.	RAP1A, member of RAS oncogene family a.	0.410
H2MA54_ORYLA	LOC101172864	ENSORLP00000015402	ENSORLP00000021855	Uncharacterized protein.	Uncharacterized protein.	0.410
H2MA54_ORYLA	PTK7	ENSORLP00000015402	ENSORLP00000026392	Uncharacterized protein.	Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.435
H2MA54_ORYLA	VANGL2	ENSORLP00000015402	ENSORLP00000003569	Uncharacterized protein.	Vang-like protein.	0.596
H2MA54_ORYLA	ctnnb1	ENSORLP00000015402	ENSORLP00000031608	Uncharacterized protein.	Catenin (cadherin-associated protein), beta 1.	0.405
H2MGX0_ORYLA	TMEM216	ENSORLP00000017864	ENSORLP00000014505	Transmembrane protein 237a.	Transmembrane protein 216.	0.403
LOC101157019	LOC101162321	ENSORLP00000029844	ENSORLP00000022375	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.940
LOC101157019	LOC101167011	ENSORLP00000029844	ENSORLP00000041511	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.901
LOC101157019	YES1	ENSORLP00000029844	ENSORLP00000014039	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.940
LOC101157019	ctnnb1	ENSORLP00000029844	ENSORLP00000031608	Tyrosine-protein kinase.	Catenin (cadherin-associated protein), beta 1.	0.934
LOC101158262	cdh2	ENSORLP00000000094	ENSORLP00000021380	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.901
LOC101158262	ctnnb1	ENSORLP00000000094	ENSORLP00000031608	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Catenin (cadherin-associated protein), beta 1.	0.903
LOC101159857	amotl2	ENSORLP00000020369	ENSORLP00000019350	Angiomotin like 2b.	Angiomotin like 2a.	0.903
LOC101160003	bmp2	ENSORLP00000030196	ENSORLP00000012259	Mothers against decapentaplegic homolog.	TGF_BETA_2 domain-containing protein.	0.753
LOC101160003	chrd	ENSORLP00000030196	ENSORLP00000011912	Mothers against decapentaplegic homolog.	Chordin; Belongs to the chordin family.	0.578
LOC101160003	ctnnb1	ENSORLP00000030196	ENSORLP00000031608	Mothers against decapentaplegic homolog.	Catenin (cadherin-associated protein), beta 1.	0.425
LOC101160069	LOC101171428	ENSORLP00000011063	ENSORLP00000013980	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	FZ domain-containing protein.	0.824
LOC101160069	PTK7	ENSORLP00000011063	ENSORLP00000026392	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.544