STRINGSTRING
pdgfc pdgfc LOC101172160 LOC101172160 ppib ppib LOC101160197 LOC101160197 bmpr2 bmpr2 LOC101167327 LOC101167327 cyp26b1 cyp26b1 LOC101162917 LOC101162917 sh2b3 sh2b3 kat2a kat2a itgb6 itgb6 ankrd11 ankrd11 SEMA4D SEMA4D LOC101167529 LOC101167529 vkorc1 vkorc1 SRC SRC anxa6 anxa6 ebp ebp H2LWC6_ORYLA H2LWC6_ORYLA trim45 trim45 LOC101160069 LOC101160069 pex7 pex7 LOC101163577 LOC101163577 LOC101172843 LOC101172843 LOC101170217 LOC101170217 mcph1 mcph1 foxn3 foxn3 LOC101172732 LOC101172732 LOC101159205 LOC101159205 ptpn6 ptpn6 srf srf LOC101159060 LOC101159060 bmp4 bmp4 atg9a atg9a LOC101162832 LOC101162832 phex phex serpinh1 serpinh1 zmpste24 zmpste24 LOC101170303 LOC101170303 LOC101161968 LOC101161968 LOC101170140 LOC101170140 LOC101165235 LOC101165235 evc evc msx1 msx1 dhrs3 dhrs3 sp5 sp5 LOC101172864 LOC101172864 LOC101170824 LOC101170824 chad chad atp6ap1 atp6ap1 frem1 frem1 bbx bbx ift80 ift80 tsku tsku LOC100529177 LOC100529177 gp1bb gp1bb MEF2D MEF2D gnptab gnptab ext2 ext2 LOC101165801 LOC101165801 LOC101160143 LOC101160143 LOC101171906 LOC101171906 LOC105358811 LOC105358811 LOC101174373 LOC101174373 LOC101168870 LOC101168870 LOC101170808 LOC101170808 trip11 trip11 wnt5b wnt5b edar edar nsd2 nsd2 rab23 rab23 ptprc ptprc H2L3P1_ORYLA H2L3P1_ORYLA sulf1 sulf1 LOC101164480 LOC101164480 ABI1 ABI1 mbtps2 mbtps2 fgf18 fgf18 ptpn11 ptpn11 LOC101174256 LOC101174256 LOC101163346 LOC101163346 lepr lepr TGFBR2 TGFBR2 slc38a10 slc38a10 LOC101171247 LOC101171247 LOC101175197 LOC101175197 LOC105357487 LOC105357487 med1 med1 smpd3 smpd3 fgf4 fgf4
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pdgfcPlatelet derived growth factor c; Belongs to the PDGF/VEGF growth factor family. (342 aa)
LOC101172160Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
ppibPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
LOC101160197E1A binding protein p300 a. (2781 aa)
bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1056 aa)
LOC101167327FAM20C golgi associated secretory pathway kinase. (554 aa)
cyp26b1Cytochrome P450 26B1; Belongs to the cytochrome P450 family. (512 aa)
LOC101162917Fras1 related extracellular matrix 1b. (1904 aa)
sh2b3SH2B adaptor protein 3. (724 aa)
kat2aHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (810 aa)
itgb6Integrin beta; Belongs to the integrin beta chain family. (757 aa)
ankrd11Ankyrin repeat domain 11. (2833 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (903 aa)
LOC101167529RAP1A, member of RAS oncogene family b. (185 aa)
vkorc1Vitamin K epoxide reductase complex, subunit 1. (167 aa)
SRCTyrosine-protein kinase. (544 aa)
anxa6Annexin. (699 aa)
ebpEBP cholestenol delta-isomerase. (259 aa)
H2LWC6_ORYLAUncharacterized protein. (260 aa)
trim45Tripartite motif containing 45. (571 aa)
LOC101160069Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (448 aa)
pex7Peroxisomal biogenesis factor 7. (326 aa)
LOC101163577FAM20C golgi associated secretory pathway kinase a. (568 aa)
LOC101172843Uncharacterized protein. (543 aa)
LOC101170217Abl-interactor 1b. (496 aa)
mcph1Uncharacterized protein. (590 aa)
foxn3Checkpoint suppressor 1. (478 aa)
LOC101172732Glycoprotein IX (platelet). (248 aa)
LOC101159205Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (794 aa)
ptpn6Protein tyrosine phosphatase non-receptor type 6. (582 aa)
srfSerum response factor b. (611 aa)
LOC101159060Leucine rich repeat containing 17. (456 aa)
bmp4Bone morphogenetic protein 4. (441 aa)
atg9aAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (850 aa)
LOC101162832Extracellular sulfatase. (885 aa)
phexPhosphate regulating endopeptidase homolog, X-linked. (719 aa)
serpinh1Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b; Belongs to the serpin family. (445 aa)
zmpste24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (467 aa)
LOC101170303Semaphorin 4e; Belongs to the semaphorin family. (768 aa)
LOC101161968Si:ch211-129c21.1; Belongs to the semaphorin family. (803 aa)
LOC101170140Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (392 aa)
LOC101165235ATPase H+ transporting accessory protein 1b. (446 aa)
evcUncharacterized protein. (984 aa)
msx1Muscle segment homeobox 1a. (275 aa)
dhrs3Dehydrogenase/reductase (SDR family) member 3b; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa)
sp5Sp5 transcription factor a. (371 aa)
LOC101172864Uncharacterized protein. (255 aa)
LOC101170824Uncharacterized protein. (867 aa)
chadChondroadherin. (359 aa)
atp6ap1ATPase H+ transporting accessory protein 1a. (482 aa)
frem1Fras1 related extracellular matrix 1a. (2073 aa)
bbxBBX high mobility group box domain containing. (815 aa)
ift80Intraflagellar transport 80 homolog (Chlamydomonas). (786 aa)
tskuTsukushi small leucine rich proteoglycan homolog (Xenopus laevis). (352 aa)
LOC100529177Gla domain-containing protein. (222 aa)
gp1bbGlycoprotein Ib platelet subunit beta. (207 aa)
MEF2DMyocyte enhancer factor 2D. (562 aa)
gnptabN-acetylglucosamine-1-phosphate transferase subunits alpha and beta. (1234 aa)
ext2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (719 aa)
LOC101165801NGFI-A binding protein 2 (EGR1 binding protein 2). (495 aa)
LOC101160143Uncharacterized protein. (1132 aa)
LOC101171906Golgi glycoprotein 1a. (1198 aa)
LOC105358811MADS-box domain-containing protein. (552 aa)
LOC101174373Myocyte enhancer factor 2d. (614 aa)
LOC101168870E1A binding protein p300 b. (2760 aa)
LOC101170808Epiphycan. (322 aa)
trip11Thyroid hormone receptor interactor 11. (1959 aa)
wnt5bProtein Wnt-5b; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity). (436 aa)
edarTumor necrosis factor receptor superfamily member EDAR; Receptor for EDA (By similarity). May mediate the activation of NF-kappa-B and JNK. (514 aa)
nsd2Nuclear receptor binding SET domain protein 2. (1283 aa)
rab23RAB23, member RAS oncogene family. (235 aa)
ptprcProtein tyrosine phosphatase receptor type C. (1343 aa)
H2L3P1_ORYLAExtracellular matrix protein 1a. (122 aa)
sulf1Sulfatase 1. (1151 aa)
LOC101164480Tyrosine-protein kinase. (551 aa)
ABI1Abl-interactor 1a. (641 aa)
mbtps2Membrane-bound transcription factor peptidase, site 2. (1155 aa)
fgf18Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
ptpn11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa)
LOC101174256Phosphatase, orphan 2. (244 aa)
LOC101163346Bone morphogenetic protein 16. (516 aa)
leprLeptin recepter. (1074 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (540 aa)
slc38a10Solute carrier family 38 member 10. (1083 aa)
LOC101171247RAP1A, member of RAS oncogene family a. (202 aa)
LOC101175197Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (809 aa)
LOC105357487Activin_recp domain-containing protein. (762 aa)
med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1782 aa)
smpd3Sphingomyelin phosphodiesterase 3, neutral. (716 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (188 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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