(16 nodes) Lung morphogenesis network (Oryzias latipes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101171361	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (305 aa)
	LOC101171145	Sprouty RTK signaling antagonist 2. (342 aa)
	LOC101164972	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
	hhip	Hedgehog interacting protein. (703 aa)
	hps1	HPS1 biogenesis of lysosomal organelles complex 3 subunit 1. (680 aa)
	wnt2bb	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
	dag1	Dystroglycan 1. (868 aa)
	srf	Serum response factor b. (611 aa)
	ctsh	Cathepsin H; Belongs to the peptidase C1 family. (324 aa)
	tcf21	Transcription factor 21. (171 aa)
	LOC105358811	MADS-box domain-containing protein. (552 aa)
	LOC101174943	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family. (2042 aa)
	LOC101165732	Peptidase S72 domain-containing protein. (901 aa)
	ctsz	Cathepsin Z; Belongs to the peptidase C1 family. (355 aa)
	stk40	Serine/threonine kinase 40. (442 aa)
	TGFBR2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (540 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101165732	dag1	ENSORLP00000037673	ENSORLP00000013717	Peptidase S72 domain-containing protein.	Dystroglycan 1.	0.902
LOC101171361	ctsh	ENSORLP00000004777	ENSORLP00000029179	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.	Cathepsin H; Belongs to the peptidase C1 family.	0.483
LOC105358811	srf	ENSORLP00000031967	ENSORLP00000016334	MADS-box domain-containing protein.	Serum response factor b.	0.905
ctsh	LOC101171361	ENSORLP00000029179	ENSORLP00000004777	Cathepsin H; Belongs to the peptidase C1 family.	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.	0.483
ctsh	ctsz	ENSORLP00000029179	ENSORLP00000038800	Cathepsin H; Belongs to the peptidase C1 family.	Cathepsin Z; Belongs to the peptidase C1 family.	0.483
ctsz	ctsh	ENSORLP00000038800	ENSORLP00000029179	Cathepsin Z; Belongs to the peptidase C1 family.	Cathepsin H; Belongs to the peptidase C1 family.	0.483
dag1	LOC101165732	ENSORLP00000013717	ENSORLP00000037673	Dystroglycan 1.	Peptidase S72 domain-containing protein.	0.902
srf	LOC105358811	ENSORLP00000016334	ENSORLP00000031967	Serum response factor b.	MADS-box domain-containing protein.	0.905