(92 nodes) Skeletal muscle organ development network (Oryzias latipes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101157279	Uncharacterized protein. (619 aa)
	LOC101165461	Myosin IXAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2214 aa)
	H2L8C2_ORYLA	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1125 aa)
	LOC101166743	HP domain-containing protein. (1630 aa)
	HOMER1	Homer scaffold protein 1. (376 aa)
	LOC101160197	E1A binding protein p300 a. (2781 aa)
	ripor3	RIPOR family member 3. (787 aa)
	LOC111949086	BTB domain-containing protein. (644 aa)
	LOC101161247	SET and MYND domain containing 1b. (489 aa)
	MYOZ1	Myozenin 1. (315 aa)
	LOC101164848	Supervillin d. (1481 aa)
	r3hdm2	R3H domain containing 2. (1069 aa)
	nphs1	NPHS1 adhesion molecule, nephrin. (1180 aa)
	LOC101164517	Ankyrin repeat domain 33ba. (535 aa)
	lamc1	Uncharacterized protein. (1595 aa)
	p2rx2	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (412 aa)
	hoxc8	Homeobox C10a. (376 aa)
	LOC101161576	RNA binding motif protein 24b. (237 aa)
	msc	Musculin (activated B-cell factor-1). (166 aa)
	popdc2	Popeye domain containing 2. (379 aa)
	LOC101163175	Homer scaffold protein 1b. (359 aa)
	unc45b	Unc-45 myosin chaperone B. (931 aa)
	LOC101166589	Kelch-like family member 40b. (612 aa)
	shh	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (414 aa)
	cemip2	Cell migration inducing hyaluronidase 2. (1386 aa)
	dag1	Dystroglycan 1. (868 aa)
	LOC101159335	SET and MYND domain containing 2a. (435 aa)
	bin3	Bridging integrator 3. (251 aa)
	LOC101173073	Uncharacterized protein. (478 aa)
	LOC101163271	RNA binding protein fox-1 homolog; RNA-binding protein that regulates alternative splicing events. (387 aa)
	LOC101156509	Uncharacterized protein. (639 aa)
	dner	Delta/notch-like EGF repeat containing. (757 aa)
	LOC101164434	Kelch-like family member 40a. (651 aa)
	hlx	H2.0-like homeo box 1 (Drosophila). (387 aa)
	LOC101168893	Kell metallo-endopeptidase (Kell blood group). (799 aa)
	rbm24	RNA binding motif protein 24a. (232 aa)
	LOC101158568	QKI, KH domain containing, RNA binding a. (343 aa)
	LOC101168402	Ankyrin repeat domain 33Bb. (528 aa)
	ripor2	RHO family interacting cell polarization regulator 2. (1127 aa)
	LMOD3	Leiomodin 3. (643 aa)
	smo	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (828 aa)
	gtf3c5	General transcription factor IIIC, polypeptide 5. (530 aa)
	selenon	Selenoprotein N. (555 aa)
	smyd2	SET and MYND domain containing 2b. (447 aa)
	H2MJT0_ORYLA	Uncharacterized protein. (589 aa)
	LOC101157720	Kruppel-like factor 5 like. (424 aa)
	six1	SIX homeobox 1a. (284 aa)
	myog	Myogenin. (248 aa)
	LOC101167500	Myosin, light chain 1, alkali; skeletal, fast. (194 aa)
	disp1	Dispatched homolog 1 (Drosophila). (1362 aa)
	myf5	Myogenic factor. (240 aa)
	myf6	Myogenic factor 6. (253 aa)
	LOC101171790	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (457 aa)
	klhl41	Kelch-like family member 41a. (597 aa)
	cdk5	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	LOC101169259	Ankyrin repeat and SOCS box containing 2a, tandem duplicate 1. (639 aa)
	LOC101170393	Myozenin 2b. (215 aa)
	popdc3	Popeye domain containing 3. (303 aa)
	atf3	Activating transcription factor 3. (212 aa)
	phox2b	Paired like homeobox 2Bb. (285 aa)
	Nf1	Uncharacterized protein. (506 aa)
	LOC101171744	Ankyrin repeat domain 33Aa. (449 aa)
	MEF2D	Myocyte enhancer factor 2D. (562 aa)
	meox2	Mesenchyme homeobox 2a. (366 aa)
	klf5	Progesterone immunomodulatory binding factor 1. (498 aa)
	taz	Tafazzin family protein; Belongs to the taffazin family. (262 aa)
	mstn	TGF_BETA_2 domain-containing protein. (424 aa)
	LOC101165521	Myozenin 2a. (267 aa)
	hlf	HLF transcription factor, PAR bZIP family member b. (317 aa)
	mylpf	Myosin light chain, phosphorylatable, fast skeletal muscle a. (297 aa)
	tcf21	Transcription factor 21. (171 aa)
	LOC101168331	Uncharacterized protein. (312 aa)
	bves	Blood vessel epicardial substance. (356 aa)
	LOC101174373	Myocyte enhancer factor 2d. (614 aa)
	LOC101168870	E1A binding protein p300 b. (2760 aa)
	LOC105357454	Myogenic factor. (245 aa)
	ENSORLP00000033705	Spatacsin_C domain-containing protein. (1073 aa)
	stac3	SH3 and cysteine rich domain 3. (346 aa)
	gpcpd1	Glycerophosphocholine phosphodiesterase 1. (667 aa)
	LOC101157753	Ankyrin repeat and SOCS box containing 2b. (581 aa)
	LOC101173138	Ankyrin repeat domain 33Ab. (448 aa)
	rb1	Retinoblastoma 1. (916 aa)
	LOC101156720	R3H domain containing 1. (996 aa)
	LOC101165732	Peptidase S72 domain-containing protein. (901 aa)
	gdf5	Growth differentiation factor 5. (567 aa)
	LOC101171064	Growth differentiation factor 6a. (437 aa)
	lamc3	Laminin, gamma 3. (1645 aa)
	ENSORLP00000039489	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (198 aa)
	LOC101171509	Uncharacterized protein. (1003 aa)
	svil	Supervillin a. (2193 aa)
	ENSORLP00000045591	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (130 aa)
	myod1	Myogenic factor. (297 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSORLP00000039489	ENSORLP00000045591	ENSORLP00000039489	ENSORLP00000045591	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.507
ENSORLP00000039489	H2L8C2_ORYLA	ENSORLP00000039489	ENSORLP00000002093	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.947
ENSORLP00000045591	ENSORLP00000039489	ENSORLP00000045591	ENSORLP00000039489	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.507
ENSORLP00000045591	H2L8C2_ORYLA	ENSORLP00000045591	ENSORLP00000002093	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.507
ENSORLP00000045591	LOC101165461	ENSORLP00000045591	ENSORLP00000002083	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Myosin IXAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.507
ENSORLP00000045591	LOC101165732	ENSORLP00000045591	ENSORLP00000037673	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Peptidase S72 domain-containing protein.	0.484
ENSORLP00000045591	dag1	ENSORLP00000045591	ENSORLP00000013717	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Dystroglycan 1.	0.484
H2L8C2_ORYLA	ENSORLP00000039489	ENSORLP00000002093	ENSORLP00000039489	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.947
H2L8C2_ORYLA	ENSORLP00000045591	ENSORLP00000002093	ENSORLP00000045591	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.507
H2MJT0_ORYLA	Nf1	ENSORLP00000018929	ENSORLP00000026133	Uncharacterized protein.	Uncharacterized protein.	0.943
LMOD3	LOC101165521	ENSORLP00000016913	ENSORLP00000029347	Leiomodin 3.	Myozenin 2a.	0.520
LMOD3	LOC101167500	ENSORLP00000016913	ENSORLP00000020004	Leiomodin 3.	Myosin, light chain 1, alkali; skeletal, fast.	0.595
LMOD3	LOC101170393	ENSORLP00000016913	ENSORLP00000024234	Leiomodin 3.	Myozenin 2b.	0.520
LMOD3	mylpf	ENSORLP00000016913	ENSORLP00000030314	Leiomodin 3.	Myosin light chain, phosphorylatable, fast skeletal muscle a.	0.497
LOC101157720	LOC101160197	ENSORLP00000019259	ENSORLP00000003103	Kruppel-like factor 5 like.	E1A binding protein p300 a.	0.483
LOC101157720	LOC101168870	ENSORLP00000019259	ENSORLP00000032567	Kruppel-like factor 5 like.	E1A binding protein p300 b.	0.483
LOC101158568	LOC101163271	ENSORLP00000015716	ENSORLP00000014121	QKI, KH domain containing, RNA binding a.	RNA binding protein fox-1 homolog; RNA-binding protein that regulates alternative splicing events.	0.521
LOC101160197	LOC101157720	ENSORLP00000003103	ENSORLP00000019259	E1A binding protein p300 a.	Kruppel-like factor 5 like.	0.483
LOC101160197	LOC101168331	ENSORLP00000003103	ENSORLP00000031698	E1A binding protein p300 a.	Uncharacterized protein.	0.483
LOC101160197	LOC101174373	ENSORLP00000003103	ENSORLP00000031999	E1A binding protein p300 a.	Myocyte enhancer factor 2d.	0.462