STRINGSTRING
LOC101157279 LOC101157279 LOC101157631 LOC101157631 Fgf1 Fgf1 LOC101157923 LOC101157923 ppp3r1 ppp3r1 fgf7 fgf7 LOC101160197 LOC101160197 bmpr2 bmpr2 zfpm2 zfpm2 LOC101171361 LOC101171361 itgb6 itgb6 dlx3 dlx3 LOC101171145 LOC101171145 axin1 axin1 H2LL82_ORYLA H2LL82_ORYLA LOC101164972 LOC101164972 LOC101161650 LOC101161650 eda eda lef1 lef1 hhip hhip hps1 hps1 msc msc wnt2bb wnt2bb LOC101156989 LOC101156989 sav1 sav1 aimp2 aimp2 LOC101170530 LOC101170530 phf14 phf14 tab1 tab1 dag1 dag1 H2M6M6_ORYLA H2M6M6_ORYLA Hydin Hydin srf srf LOC101157986 LOC101157986 phex phex LOC101169939 LOC101169939 bag6 bag6 LOC101165887 LOC101165887 adamtsl2 adamtsl2 SP3 SP3 pkd1 pkd1 phox2b phox2b PTK7 PTK7 LOC101168674 LOC101168674 hspb11 hspb11 ctsh ctsh tcf21 tcf21 atxn1l atxn1l LOC105358811 LOC105358811 timeless timeless LOC101168870 LOC101168870 LOC101160446 LOC101160446 LOC101174943 LOC101174943 itga3 itga3 LOC101165732 LOC101165732 LOC101155494 LOC101155494 pkdcc pkdcc fgf18 fgf18 ctsz ctsz errfi1 errfi1 stk40 stk40 LOC101174785 LOC101174785 LOC101155067 LOC101155067 TGFBR2 TGFBR2 wdpcp wdpcp LOC105357487 LOC105357487 smpd3 smpd3 rspo2 rspo2 LOC101174756 LOC101174756
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101157279Uncharacterized protein. (619 aa)
LOC101157631Transforming growth factor beta; Belongs to the TGF-beta family. (444 aa)
Fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (159 aa)
LOC101157923Insulin-like growth factor binding protein 5a. (253 aa)
ppp3r1Uncharacterized protein. (170 aa)
fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (205 aa)
LOC101160197E1A binding protein p300 a. (2781 aa)
bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1056 aa)
zfpm2Zinc finger protein, FOG family member 2a. (1170 aa)
LOC101171361Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (305 aa)
itgb6Integrin beta; Belongs to the integrin beta chain family. (757 aa)
dlx3Distal-less homeobox 3b. (278 aa)
LOC101171145Sprouty RTK signaling antagonist 2. (342 aa)
axin1Axin 1. (854 aa)
H2LL82_ORYLASi:ch211-267e7.3. (388 aa)
LOC101164972Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
LOC101161650Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (157 aa)
edaEctodysplasin A; Belongs to the tumor necrosis factor family. (364 aa)
lef1Lymphoid enhancer-binding factor 1. (379 aa)
hhipHedgehog interacting protein. (703 aa)
hps1HPS1 biogenesis of lysosomal organelles complex 3 subunit 1. (680 aa)
mscMusculin (activated B-cell factor-1). (166 aa)
wnt2bbProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
LOC101156989Endothelin 2. (166 aa)
sav1Salvador family WW domain containing protein 1. (391 aa)
aimp2Aminoacyl tRNA synthetase complex interacting multifunctional protein 2. (298 aa)
LOC101170530Ring finger and CCCH-type domains 2. (1143 aa)
phf14PHD finger protein 14. (923 aa)
tab1TGF-beta activated kinase 1/MAP3K7 binding protein 1. (504 aa)
dag1Dystroglycan 1. (868 aa)
H2M6M6_ORYLAStructural maintenance of chromosomes flexible hinge domain containing 1. (1384 aa)
HydinUncharacterized protein. (694 aa)
srfSerum response factor b. (611 aa)
LOC101157986Sp3b transcription factor. (614 aa)
phexPhosphate regulating endopeptidase homolog, X-linked. (719 aa)
LOC101169939RPGRIP1 like. (1240 aa)
bag6BCL2 associated athanogene 6. (1195 aa)
LOC101165887ETS transcription factor ELK1. (571 aa)
adamtsl2ADAMTS-like 2. (903 aa)
SP3Sp3a transcription factor. (668 aa)
pkd1Uncharacterized protein. (4114 aa)
phox2bPaired like homeobox 2Bb. (285 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1072 aa)
LOC101168674Uncharacterized protein. (179 aa)
hspb11Zgc:158640. (134 aa)
ctshCathepsin H; Belongs to the peptidase C1 family. (324 aa)
tcf21Transcription factor 21. (171 aa)
atxn1lAtaxin 1-like. (815 aa)
LOC105358811MADS-box domain-containing protein. (552 aa)
timelessTimeless circadian clock. (1244 aa)
LOC101168870E1A binding protein p300 b. (2760 aa)
LOC101160446Si:dkey-91i10.2. (1200 aa)
LOC101174943Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family. (2042 aa)
itga3Integrin, alpha 3b; Belongs to the integrin alpha chain family. (1075 aa)
LOC101165732Peptidase S72 domain-containing protein. (901 aa)
LOC101155494Uncharacterized protein. (883 aa)
pkdccProtein kinase domain containing, cytoplasmic b. (473 aa)
fgf18Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
ctszCathepsin Z; Belongs to the peptidase C1 family. (355 aa)
errfi1ERBB receptor feedback inhibitor 1a. (422 aa)
stk40Serine/threonine kinase 40. (442 aa)
LOC101174785TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (587 aa)
LOC101155067Insulin-like growth factor binding protein 5a. (266 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (540 aa)
wdpcpWD repeat containing planar cell polarity effector. (686 aa)
LOC105357487Activin_recp domain-containing protein. (762 aa)
smpd3Sphingomyelin phosphodiesterase 3, neutral. (716 aa)
rspo2R-spondin-2. (245 aa)
LOC101174756Uncharacterized protein. (115 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.