STRINGSTRING
kremen1 kremen1 LOC101160793 LOC101160793 csnk1g1 csnk1g1 USP34 USP34 LOC100125464 LOC100125464 pfdn5 pfdn5 tpbg tpbg TLE3 TLE3 LOC101163121 LOC101163121 cthrc1 cthrc1 LOC105356509 LOC105356509 VANGL2 VANGL2 dab2 dab2 usp50 usp50 usp8 usp8 H2LE41_ORYLA H2LE41_ORYLA ILK ILK H2LHW8_ORYLA H2LHW8_ORYLA bambi bambi ppm1b ppm1b LOC101172012 LOC101172012 axin1 axin1 TLE4 TLE4 bicc1 bicc1 ubac2 ubac2 LOC101168937 LOC101168937 FAM53B FAM53B RNF146 RNF146 rspo3 rspo3 LOC101172518 LOC101172518 eda eda LOC100049394 LOC100049394 CCNY CCNY LOC101159369 LOC101159369 amer2 amer2 LOC101168720 LOC101168720 nkx2-5 nkx2-5 LOC101157602 LOC101157602 usp47 usp47 sfrp5 sfrp5 LOC101171257 LOC101171257 notum notum nkd2 nkd2 LOC101175090 LOC101175090 sfrp2 sfrp2 tmem131l tmem131l gprc5b gprc5b LOC101165003 LOC101165003 LOC101159441 LOC101159441 LOC101172235 LOC101172235 H2LYZ3_ORYLA H2LYZ3_ORYLA LOC101170947 LOC101170947 tmem170b tmem170b pin1 pin1 H2M0Q7_ORYLA H2M0Q7_ORYLA H2M1P0_ORYLA H2M1P0_ORYLA dact1 dact1 LOC101156612 LOC101156612 lmbr1 lmbr1 frmd8 frmd8 fzd4 fzd4 LOC101170581 LOC101170581 H2M614_ORYLA H2M614_ORYLA LOC101171428 LOC101171428 adgra2 adgra2 lzts2 lzts2 atp6ap2 atp6ap2 LOC101164686 LOC101164686 sox13 sox13 chd8 chd8 wnt11 wnt11 apc2 apc2 LOC101157515 LOC101157515 LOC101168409 LOC101168409 cyld cyld LOC101163809 LOC101163809 nkd1 nkd1 LOC101161673 LOC101161673 LOC101161767 LOC101161767 TBL1XR1 TBL1XR1 mks1 mks1 csnk1e csnk1e rspo1 rspo1 LOC101162828 LOC101162828 GID8 GID8 LOC101171824 LOC101171824 LOC101156325 LOC101156325 scyl2 scyl2 stk11 stk11 znf703 znf703 ppm1a ppm1a H2MMT5_ORYLA H2MMT5_ORYLA LOC101167083 LOC101167083 tnn tnn gskip gskip sostdc1 sostdc1 LOC101157205 LOC101157205 tle5 tle5 ttc21b ttc21b H2MRC6_ORYLA H2MRC6_ORYLA csnk1d csnk1d lats1 lats1 LOC101170720 LOC101170720 Grem1 Grem1 gsk3b gsk3b jade1 jade1 lrrk2 lrrk2 csnk1a1 csnk1a1 LOC101159459 LOC101159459 PTK7 PTK7 ccny ccny LOC101162607 LOC101162607 sox7 sox7 LOC101171501 LOC101171501 apc apc LOC101157691 LOC101157691 LOC101157048 LOC101157048 ddit3 ddit3 lmbr1l lmbr1l CSNK1G2 CSNK1G2 ENSORLP00000032097 ENSORLP00000032097 LOC101158122 LOC101158122 LOC101157442 LOC101157442 LOC101159847 LOC101159847 LOC105356552 LOC105356552 RNF220 RNF220 lats2 lats2 LOC101158175 LOC101158175 ushbp1 ushbp1 AXIN2 AXIN2 LOC101164849 LOC101164849 LOC101159317 LOC101159317 cby1 cby1 ankrd6 ankrd6 LOC101168449 LOC101168449 lgr5 lgr5 LOC101172590 LOC101172590 LOC101155494 LOC101155494 nle1 nle1 dact3 dact3 LOC101169782 LOC101169782 LOC101167576 LOC101167576 ZNF703 ZNF703 LOC101166883 LOC101166883 wls wls LOC101168073 LOC101168073 ubr5 ubr5 sfrp1 sfrp1 tmem64 tmem64 dkk2 dkk2 LOC105353570 LOC105353570 shisa3 shisa3 LOC101174248 LOC101174248 lgr4 lgr4 ENSORLP00000042326 ENSORLP00000042326 ENSORLP00000042504 ENSORLP00000042504 LYPD6 LYPD6 LOC101156518 LOC101156518 znrf3 znrf3 gpc5 gpc5 LOC101162248 LOC101162248 PRDM15 PRDM15 LOC101154844 LOC101154844 LOC101160344 LOC101160344 LOC101166399 LOC101166399 rspo2 rspo2 nphp4 nphp4 ENSORLP00000045591 ENSORLP00000045591 prkn prkn ENSORLP00000045928 ENSORLP00000045928 LOC101165057 LOC101165057
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
kremen1Kringle containing transmembrane protein 1. (425 aa)
LOC101160793Transmembrane protein 198b. (362 aa)
csnk1g1Casein kinase 1, gamma 1; Belongs to the protein kinase superfamily. (472 aa)
USP34Ubiquitin specific peptidase 34; Belongs to the peptidase C19 family. (2781 aa)
LOC100125464Uncharacterized protein. (736 aa)
pfdn5Prefoldin 5. (154 aa)
tpbgTrophoblast glycoprotein b. (375 aa)
TLE3TLE family member 3, transcriptional corepressor. (783 aa)
LOC101163121Cyclin Y-like 1; Belongs to the cyclin family. (432 aa)
cthrc1Collagen triple helix repeat containing 1b. (229 aa)
LOC105356509Casein kinase 1, epsilon; Belongs to the protein kinase superfamily. (416 aa)
VANGL2Vang-like protein. (525 aa)
dab2DAB adaptor protein 2. (761 aa)
usp50Ubiquitin carboxyl-terminal hydrolase. (745 aa)
usp8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1078 aa)
H2LE41_ORYLALRRCT domain-containing protein. (319 aa)
ILKIntegrin linked kinase. (452 aa)
H2LHW8_ORYLATrophoblast glycoprotein-like. (409 aa)
bambiBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (257 aa)
ppm1bProtein phosphatase, Mg2+/Mn2+ dependent, 1Ba. (402 aa)
LOC101172012Uncharacterized protein. (452 aa)
axin1Axin 1. (854 aa)
TLE4Uncharacterized protein. (756 aa)
bicc1BicC family RNA binding protein 1a. (963 aa)
ubac2UBA domain containing 2. (332 aa)
LOC101168937Ring finger protein 220b. (554 aa)
FAM53BUncharacterized protein. (448 aa)
RNF146Ring finger protein 146. (375 aa)
rspo3R-spondin-3. (328 aa)
LOC101172518Dickkopf WNT signaling pathway inhibitor 1a. (244 aa)
edaEctodysplasin A; Belongs to the tumor necrosis factor family. (364 aa)
LOC100049394TLE family member 3, transcriptional corepressor. (754 aa)
CCNYCYCLIN domain-containing protein; Belongs to the cyclin family. (347 aa)
LOC101159369Protein phosphatase, Mg2+/Mn2+ dependent, 1Na (putative). (447 aa)
amer2APC membrane recruitment protein 2. (574 aa)
LOC101168720Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (438 aa)
nkx2-5Homeobox domain-containing protein. (319 aa)
LOC101157602Dickkopf WNT signaling pathway inhibitor 3a. (266 aa)
usp47Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1365 aa)
sfrp5Secreted frizzled-related protein 5. (319 aa)
LOC101171257Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (343 aa)
notumNotum, palmitoleoyl-protein carboxylesterase a. (496 aa)
nkd2NKD inhibitor of WNT signaling pathway 2a. (460 aa)
LOC101175090Sclerostin domain containing 1b. (188 aa)
sfrp2Secreted frizzled-related protein 2. (290 aa)
tmem131lTransmembrane 131 like. (1513 aa)
gprc5bG protein-coupled receptor, class C, group 5, member Ba. (400 aa)
LOC101165003Transducin (beta)-like 1 X-linked receptor 1b. (528 aa)
LOC101159441Axin 2 (conductin, axil). (841 aa)
LOC101172235Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (445 aa)
H2LYZ3_ORYLAUncharacterized protein. (267 aa)
LOC101170947Protein phosphatase, Mg2+/Mn2+ dependent, 1Nb (putative). (430 aa)
tmem170bTransmembrane protein 170B. (127 aa)
pin1Peptidyl-prolyl cis-trans isomerase. (156 aa)
H2M0Q7_ORYLAAPC membrane recruitment protein 1. (960 aa)
H2M1P0_ORYLAGlypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (583 aa)
dact1Dishevelled binding antagonist of beta catenin 1. (870 aa)
LOC101156612Protein phosphatase, Mg2+/Mn2+ dependent, 1Bb. (474 aa)
lmbr1Limb development membrane protein 1; Belongs to the LIMR family. (492 aa)
frmd8FERM domain containing 8. (473 aa)
fzd4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (529 aa)
LOC101170581Glypican 5b; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (616 aa)
H2M614_ORYLAANK_REP_REGION domain-containing protein. (281 aa)
LOC101171428FZ domain-containing protein. (337 aa)
adgra2Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1368 aa)
lzts2Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family. (709 aa)
atp6ap2ATPase H+ transporting accessory protein 2. (374 aa)
LOC101164686OTU deubiquitinase with linear linkage specificity a. (712 aa)
sox13SRY-box transcription factor 13. (588 aa)
chd8Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2553 aa)
wnt11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
apc2APC regulator of WNT signaling pathway 2. (2227 aa)
LOC101157515Notum pectinacetylesterase 2. (507 aa)
LOC101168409Frizzled related protein. (314 aa)
cyldCylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family. (918 aa)
LOC101163809Cylindromatosis (turban tumor syndrome), b. (707 aa)
nkd1NKD inhibitor of WNT signaling pathway 1. (446 aa)
LOC101161673Apolipoprotein Eb. (265 aa)
LOC101161767TLE_N domain-containing protein. (203 aa)
TBL1XR1Uncharacterized protein. (515 aa)
mks1MKS transition zone complex subunit 1. (563 aa)
csnk1eProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (413 aa)
rspo1Uncharacterized protein. (270 aa)
LOC101162828Mesoderm posterior ba. (262 aa)
GID8Uncharacterized protein. (229 aa)
LOC101171824DUF4203 domain-containing protein. (342 aa)
LOC101156325DUF4203 domain-containing protein. (334 aa)
scyl2SCY1 like pseudokinase 2. (925 aa)
stk11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (438 aa)
znf703Zinc finger protein 703. (587 aa)
ppm1aProtein phosphatase, Mg2+/Mn2+ dependent, 1Aa. (388 aa)
H2MMT5_ORYLAGlypican 5c; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (359 aa)
LOC101167083Transmembrane protein 198a. (389 aa)
tnnTenascin N. (834 aa)
gskipGsk3b interacting protein. (173 aa)
sostdc1Sclerostin domain containing 1a. (218 aa)
LOC101157205TLE family member 2, transcriptional corepressor a. (776 aa)
tle5TLE family member 5, transcriptional modulator. (196 aa)
ttc21bTetratricopeptide repeat domain 21B. (1321 aa)
H2MRC6_ORYLARing finger protein 146. (316 aa)
csnk1dCasein kinase 1, delta b; Belongs to the protein kinase superfamily. (405 aa)
lats1Large tumor suppressor kinase 1. (1063 aa)
LOC101170720Transducin beta like 1 X-linked. (513 aa)
Grem1Gremlin 1a, DAN family BMP antagonist. (165 aa)
gsk3bGlycogen synthase kinase 3 beta, genome duplicate a. (216 aa)
jade1Jade family PHD finger 1. (886 aa)
lrrk2Leucine-rich repeat kinase 2. (2241 aa)
csnk1a1Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily. (353 aa)
LOC101159459Uncharacterized protein. (428 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1072 aa)
ccnyCyclin Y; Belongs to the cyclin family. (356 aa)
LOC101162607Leucine zipper, putative tumor suppressor family member 3b. (1091 aa)
sox7Uncharacterized protein. (407 aa)
LOC101171501Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
apcAPC regulator of WNT signaling pathway. (2204 aa)
LOC101157691Sizzled. (283 aa)
LOC101157048WNK lysine deficient protein kinase 2. (2286 aa)
ddit3CCAAT/enhancer-binding protein-homologous protein. (308 aa)
lmbr1lLimb development membrane protein 1-like; Belongs to the LIMR family. (492 aa)
CSNK1G2Casein kinase 1 gamma 2; Belongs to the protein kinase superfamily. (415 aa)
ENSORLP00000032097Uncharacterized protein. (189 aa)
LOC101158122Poly [ADP-ribose] polymerase. (1283 aa)
LOC101157442TLE family member 2, transcriptional corepressor b. (727 aa)
LOC101159847Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family. (779 aa)
LOC105356552PH domain-containing protein. (1284 aa)
RNF220Uncharacterized protein. (266 aa)
lats2Large tumor suppressor kinase 2. (1156 aa)
LOC101158175Cyclin Y like 1; Belongs to the cyclin family. (339 aa)
ushbp1Usher syndrome 1C binding protein 1. (693 aa)
AXIN2Axin 2. (791 aa)
LOC101164849Protein FAM53B; Acts as a regulator of Wnt signaling pathway by regulating beta-catenin (ctnnb1) nuclear localization. (411 aa)
LOC101159317Trophoblast glycoprotein a. (367 aa)
cby1Chibby homolog 1 (Drosophila). (134 aa)
ankrd6Ankyrin repeat domain 6b. (705 aa)
LOC101168449Cylindromatosis (turban tumor syndrome), like; Belongs to the peptidase C19 family. (769 aa)
lgr5G_PROTEIN_RECEP_F1_2 domain-containing protein. (909 aa)
LOC101172590Bicaudal C homolog 2. (895 aa)
LOC101155494Uncharacterized protein. (883 aa)
nle1Notchless homolog 1 (Drosophila). (478 aa)
dact3Uncharacterized protein. (640 aa)
LOC101169782Insulin-like growth factor binding protein 6b. (201 aa)
LOC101167576Uncharacterized protein. (943 aa)
ZNF703Zinc finger protein 703. (557 aa)
LOC101166883X-linked inhibitor of apoptosis. (408 aa)
wlsWnt ligand secretion mediator. (554 aa)
LOC101168073Ring finger protein 220a. (379 aa)
ubr5Ubiquitin protein ligase E3 component n-recognin 5. (2859 aa)
sfrp1Uncharacterized protein. (306 aa)
tmem64Transmembrane protein 64. (352 aa)
dkk2Dickkopf WNT signaling pathway inhibitor 2. (272 aa)
LOC105353570Poly [ADP-ribose] polymerase. (1266 aa)
shisa3Shisa family member 3. (271 aa)
LOC101174248G protein-coupled receptor, class C, group 5, member Bb. (417 aa)
lgr4Leucine-rich repeat containing G protein-coupled receptor 4. (975 aa)
ENSORLP00000042326Dickkopf_N domain-containing protein. (172 aa)
ENSORLP00000042504Dickkopf WNT signaling pathway inhibitor 3b. (307 aa)
LYPD6LY6/PLAUR domain containing 6. (168 aa)
LOC101156518Uncharacterized protein. (636 aa)
znrf3Zinc and ring finger 3. (871 aa)
gpc5Glypican 5a; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (564 aa)
LOC101162248Uncharacterized protein. (227 aa)
PRDM15PR/SET domain 15. (1119 aa)
LOC101154844Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (410 aa)
LOC101160344Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily. (480 aa)
LOC101166399Apolipoprotein Ea. (262 aa)
rspo2R-spondin-2. (245 aa)
nphp4Uncharacterized protein. (1491 aa)
ENSORLP00000045591Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (130 aa)
prknE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (466 aa)
ENSORLP00000045928Catenin, beta interacting protein 1. (83 aa)
LOC101165057GID complex subunit 8 homolog b (S. cerevisiae). (228 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (30%) [HD]