STRINGSTRING
pln pln scn3b scn3b nup155 nup155 LOC101169720 LOC101169720 LOC101173369 LOC101173369 zmpste24 zmpste24 LOC101162070 LOC101162070 gja5 gja5 RNF207 RNF207 ENSORLP00000033307 ENSORLP00000033307 kcne4 kcne4 LOC101166715 LOC101166715 LOC101173191 LOC101173191 scn2b scn2b LOC101161541 LOC101161541 LOC101159760 LOC101159760
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
plnCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (53 aa)
scn3bSodium channel, voltage-gated, type III, beta. (216 aa)
nup155Nucleoporin 155. (1368 aa)
LOC101169720Sodium channel, voltage-gated, type IV, beta a. (232 aa)
LOC101173369Junction plakoglobin a. (733 aa)
zmpste24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (467 aa)
LOC101162070Sodium channel, voltage-gated, type I, beta a. (275 aa)
gja5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (371 aa)
RNF207Ring finger protein 207. (616 aa)
ENSORLP00000033307Uncharacterized protein. (126 aa)
kcne4Potassium voltage-gated channel, Isk-related family, member 4. (176 aa)
LOC101166715Uncharacterized protein; Belongs to the potassium channel family. (719 aa)
LOC101173191Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (345 aa)
scn2bSodium channel, voltage-gated, type II, beta. (220 aa)
LOC101161541Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family. (695 aa)
LOC101159760Ig-like domain-containing protein. (235 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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