(18 nodes) I-SMAD binding network (Oryzias latipes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101169523	Mothers against decapentaplegic homolog. (425 aa)
	LOC101170165	Mothers against decapentaplegic homolog. (499 aa)
	axin1	Axin 1. (854 aa)
	SMAD4	Mothers against decapentaplegic homolog. (510 aa)
	smad3	Mothers against decapentaplegic homolog. (425 aa)
	smad6	Mothers against decapentaplegic homolog. (488 aa)
	smad1	Mothers against decapentaplegic homolog. (471 aa)
	ints8	Integrator complex subunit 8. (1000 aa)
	LOC101159441	Axin 2 (conductin, axil). (841 aa)
	smad2	Mothers against decapentaplegic homolog. (473 aa)
	LOC101159109	Mothers against decapentaplegic homolog. (467 aa)
	smad9	Mothers against decapentaplegic homolog. (467 aa)
	LOC101173916	Mothers against decapentaplegic homolog. (538 aa)
	LOC101160003	Mothers against decapentaplegic homolog. (464 aa)
	AXIN2	Axin 2. (791 aa)
	LOC101155494	Uncharacterized protein. (883 aa)
	smad7	Mothers against decapentaplegic homolog. (375 aa)
	LOC101163504	Mothers against decapentaplegic homolog. (528 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AXIN2	LOC101155494	ENSORLP00000035131	ENSORLP00000038069	Axin 2.	Uncharacterized protein.	0.668
AXIN2	LOC101159441	ENSORLP00000035131	ENSORLP00000011155	Axin 2.	Axin 2 (conductin, axil).	0.552
AXIN2	axin1	ENSORLP00000035131	ENSORLP00000006039	Axin 2.	Axin 1.	0.667
LOC101155494	AXIN2	ENSORLP00000038069	ENSORLP00000035131	Uncharacterized protein.	Axin 2.	0.668
LOC101155494	LOC101159441	ENSORLP00000038069	ENSORLP00000011155	Uncharacterized protein.	Axin 2 (conductin, axil).	0.675
LOC101155494	axin1	ENSORLP00000038069	ENSORLP00000006039	Uncharacterized protein.	Axin 1.	0.552
LOC101159109	LOC101160003	ENSORLP00000019646	ENSORLP00000030196	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.737
LOC101159109	LOC101163504	ENSORLP00000019646	ENSORLP00000045202	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.979
LOC101159109	LOC101169523	ENSORLP00000019646	ENSORLP00000002748	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.900
LOC101159109	LOC101170165	ENSORLP00000019646	ENSORLP00000002767	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.937
LOC101159109	LOC101173916	ENSORLP00000019646	ENSORLP00000029700	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.979
LOC101159109	SMAD4	ENSORLP00000019646	ENSORLP00000006328	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.988
LOC101159109	smad1	ENSORLP00000019646	ENSORLP00000009247	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.736
LOC101159109	smad2	ENSORLP00000019646	ENSORLP00000014831	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.543
LOC101159109	smad3	ENSORLP00000019646	ENSORLP00000008548	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.549
LOC101159109	smad6	ENSORLP00000019646	ENSORLP00000008572	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.946
LOC101159109	smad7	ENSORLP00000019646	ENSORLP00000044215	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.937
LOC101159109	smad9	ENSORLP00000019646	ENSORLP00000028879	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.733
LOC101159441	AXIN2	ENSORLP00000011155	ENSORLP00000035131	Axin 2 (conductin, axil).	Axin 2.	0.552
LOC101159441	LOC101155494	ENSORLP00000011155	ENSORLP00000038069	Axin 2 (conductin, axil).	Uncharacterized protein.	0.675