(32 nodes) Response to interleukin-1 network (Oryzias latipes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rbmx	RNA binding motif protein X-linked. (420 aa)
	smpd1	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (604 aa)
	LOC101163093	Immunoresponsive gene 1, like. (498 aa)
	ripk2	Receptor-interacting serine-threonine kinase 2. (590 aa)
	pcsk1	Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (765 aa)
	LOC101166594	Ribosomal protein S6 kinase. (807 aa)
	LOC101157257	Uncharacterized protein. (548 aa)
	ZC3H12A	Zinc finger CCCH-type containing 12A. (270 aa)
	cited1	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1. (158 aa)
	gclc	Glutamate-cysteine ligase, catalytic subunit. (592 aa)
	LOC101170545	Zinc finger CCCH-type containing 12A. (621 aa)
	LOC101158138	Ring finger and CCCH-type domains 1b. (1116 aa)
	YTHDC2	YTH domain containing 2. (1284 aa)
	LOC101157495	Zmp:0000000936. (644 aa)
	LOC101161187	P/Homo B domain-containing protein; Belongs to the peptidase S8 family. (573 aa)
	LOC101160820	SCY domain-containing protein. (131 aa)
	LOC101167564	Ribosomal protein S6 kinase. (787 aa)
	usp10	Ubiquitin carboxyl-terminal hydrolase. (882 aa)
	map2k7	Mitogen-activated protein kinase kinase 7. (477 aa)
	LOC100301586	CD40 molecule, TNF receptor superfamily member 5. (305 aa)
	LOC105356773	Zmp:0000000936. (653 aa)
	LOC101167461	NK3 homeobox 1. (188 aa)
	LOC101170161	SCY domain-containing protein. (96 aa)
	LOC101169209	Uncharacterized protein. (283 aa)
	traf6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (569 aa)
	akap12	A kinase (PRKA) anchor protein 12b. (1419 aa)
	st18	ST18 C2H2C-type zinc finger transcription factor. (1111 aa)
	LOC101166698	Protein kinase domain-containing protein. (721 aa)
	acod1	Aconitate decarboxylase 1. (478 aa)
	tnfrsf11a	Tumor necrosis factor receptor superfamily, member 11a, NFKB activator. (639 aa)
	LOC101162278	Chemokine (C-C motif) ligand 25b. (96 aa)
	tank	TRAF family member-associated NFKB activator. (345 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC100301586	LOC101169209	ENSORLP00000033631	ENSORLP00000036862	CD40 molecule, TNF receptor superfamily member 5.	Uncharacterized protein.	0.581
LOC100301586	tnfrsf11a	ENSORLP00000033631	ENSORLP00000044345	CD40 molecule, TNF receptor superfamily member 5.	Tumor necrosis factor receptor superfamily, member 11a, NFKB activator.	0.505
LOC100301586	traf6	ENSORLP00000033631	ENSORLP00000001290	CD40 molecule, TNF receptor superfamily member 5.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.960
LOC101157257	LOC101166698	ENSORLP00000011538	ENSORLP00000040412	Uncharacterized protein.	Protein kinase domain-containing protein.	0.739
LOC101157257	LOC101169209	ENSORLP00000011538	ENSORLP00000036862	Uncharacterized protein.	Uncharacterized protein.	0.888
LOC101157257	traf6	ENSORLP00000011538	ENSORLP00000001290	Uncharacterized protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.770
LOC101157495	LOC101166698	ENSORLP00000029776	ENSORLP00000040412	Zmp:0000000936.	Protein kinase domain-containing protein.	0.739
LOC101157495	LOC101169209	ENSORLP00000029776	ENSORLP00000036862	Zmp:0000000936.	Uncharacterized protein.	0.886
LOC101157495	traf6	ENSORLP00000029776	ENSORLP00000001290	Zmp:0000000936.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.770
LOC101160820	LOC101162278	ENSORLP00000030164	ENSORLP00000044456	SCY domain-containing protein.	Chemokine (C-C motif) ligand 25b.	0.816
LOC101162278	LOC101160820	ENSORLP00000044456	ENSORLP00000030164	Chemokine (C-C motif) ligand 25b.	SCY domain-containing protein.	0.816
LOC101162278	LOC101170161	ENSORLP00000044456	ENSORLP00000036036	Chemokine (C-C motif) ligand 25b.	SCY domain-containing protein.	0.565
LOC101163093	acod1	ENSORLP00000007735	ENSORLP00000043171	Immunoresponsive gene 1, like.	Aconitate decarboxylase 1.	0.902
LOC101166594	LOC101167564	ENSORLP00000010872	ENSORLP00000031000	Ribosomal protein S6 kinase.	Ribosomal protein S6 kinase.	0.901
LOC101166698	LOC101157257	ENSORLP00000040412	ENSORLP00000011538	Protein kinase domain-containing protein.	Uncharacterized protein.	0.739
LOC101166698	LOC101157495	ENSORLP00000040412	ENSORLP00000029776	Protein kinase domain-containing protein.	Zmp:0000000936.	0.739
LOC101166698	LOC101169209	ENSORLP00000040412	ENSORLP00000036862	Protein kinase domain-containing protein.	Uncharacterized protein.	0.773
LOC101166698	LOC105356773	ENSORLP00000040412	ENSORLP00000035228	Protein kinase domain-containing protein.	Zmp:0000000936.	0.739
LOC101166698	map2k7	ENSORLP00000040412	ENSORLP00000032905	Protein kinase domain-containing protein.	Mitogen-activated protein kinase kinase 7.	0.457
LOC101166698	ripk2	ENSORLP00000040412	ENSORLP00000010554	Protein kinase domain-containing protein.	Receptor-interacting serine-threonine kinase 2.	0.614