(51 nodes) Positive regulation of leukocyte proliferation network (Oryzias latipes)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101172133	ATPase family AAA domain containing 5b. (959 aa)
	card11	Caspase recruitment domain family, member 11. (1146 aa)
	tirap	Toll-interleukin 1 receptor (TIR) domain containing adaptor protein. (252 aa)
	LOC101161479	Interleukin 12 receptor, beta 2a. (783 aa)
	ocstamp	Osteoclast stimulatory transmembrane protein. (466 aa)
	LOC101171005	Nuclear factor of activated T cells 2a. (893 aa)
	tnfsf13b	TNF superfamily member 13b; Belongs to the tumor necrosis factor family. (252 aa)
	LOC101173752	IGv domain-containing protein. (224 aa)
	H2MWT7_ORYLA	Uncharacterized protein. (246 aa)
	il6st	Uncharacterized protein. (868 aa)
	gpam	Glycerol-3-phosphate acyltransferase 1, mitochondrial. (823 aa)
	LOC101168159	Uncharacterized protein. (299 aa)
	ENSORLP00000026992	Ig-like domain-containing protein. (157 aa)
	LOC101170171	Zeta chain of T cell receptor associated protein kinase 70. (668 aa)
	LOC101168658	Uncharacterized protein. (275 aa)
	LOC101160820	SCY domain-containing protein. (131 aa)
	mpl	MPL proto-oncogene, thrombopoietin receptor. (631 aa)
	ENSORLP00000033332	Uncharacterized protein. (377 aa)
	LOC100301586	CD40 molecule, TNF receptor superfamily member 5. (305 aa)
	SLC7A1	Solute carrier family 7 member 1. (667 aa)
	ENSORLP00000034778	Uncharacterized protein. (380 aa)
	ptprc	Protein tyrosine phosphatase receptor type C. (1343 aa)
	ENSORLP00000036355	Uncharacterized protein. (102 aa)
	syk	Tyrosine-protein kinase. (624 aa)
	LOC101169209	Uncharacterized protein. (283 aa)
	ENSORLP00000037698	Uncharacterized protein. (305 aa)
	LOC101164896	Uncharacterized protein. (688 aa)
	LOC101168658-2	Uncharacterized protein. (257 aa)
	igf2	Insulin-like growth factor 2b. (212 aa)
	nck2	Cytoplasmic protein. (398 aa)
	ENSORLP00000039599	Uncharacterized protein. (486 aa)
	ENSORLP00000040878	Ig-like domain-containing protein. (126 aa)
	TGFBR2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (540 aa)
	cd276	CD276 molecule. (302 aa)
	fadd	Uncharacterized protein. (192 aa)
	il34	Interleukin 34. (236 aa)
	ENSORLP00000044779	Uncharacterized protein. (511 aa)
	sash3	SAM and SH3 domain containing 3. (391 aa)
	LOC101167049	CD40 ligand; Belongs to the tumor necrosis factor family. (239 aa)
	LOC101154797	Solute carrier family 7 member 1a. (647 aa)
	H2LPR9_ORYLA	HERV-H LTR-associating 2a, tandem duplicate 2. (462 aa)
	AIF1	Allograft inflammatory factor 1. (154 aa)
	ripk2	Receptor-interacting serine-threonine kinase 2. (590 aa)
	nmbr	Neuromedin B receptor; Belongs to the G-protein coupled receptor 1 family. (395 aa)
	nck1	Cytoplasmic protein. (392 aa)
	H2M2N2_ORYLA	Uncharacterized protein. (150 aa)
	1-sf	ZP domain-containing protein. (420 aa)
	LOC101166554	ATPase family AAA domain containing 5a. (1758 aa)
	dhps	Deoxyhypusine synthase. (360 aa)
	LOC101168287	Colony stimulating factor 1b (macrophage). (301 aa)
	LOC101168676	CD38 molecule. (264 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIF1	LOC101169209	ENSORLP00000008655	ENSORLP00000036862	Allograft inflammatory factor 1.	Uncharacterized protein.	0.589
AIF1	ptprc	ENSORLP00000008655	ENSORLP00000035490	Allograft inflammatory factor 1.	Protein tyrosine phosphatase receptor type C.	0.473
H2M2N2_ORYLA	LOC101167049	ENSORLP00000012678	ENSORLP00000002171	Uncharacterized protein.	CD40 ligand; Belongs to the tumor necrosis factor family.	0.429
H2M2N2_ORYLA	LOC101169209	ENSORLP00000012678	ENSORLP00000036862	Uncharacterized protein.	Uncharacterized protein.	0.728
LOC100301586	LOC101167049	ENSORLP00000033631	ENSORLP00000002171	CD40 molecule, TNF receptor superfamily member 5.	CD40 ligand; Belongs to the tumor necrosis factor family.	0.980
LOC100301586	LOC101169209	ENSORLP00000033631	ENSORLP00000036862	CD40 molecule, TNF receptor superfamily member 5.	Uncharacterized protein.	0.581
LOC100301586	LOC101173752	ENSORLP00000033631	ENSORLP00000022838	CD40 molecule, TNF receptor superfamily member 5.	IGv domain-containing protein.	0.670
LOC100301586	cd276	ENSORLP00000033631	ENSORLP00000042531	CD40 molecule, TNF receptor superfamily member 5.	CD276 molecule.	0.505
LOC100301586	fadd	ENSORLP00000033631	ENSORLP00000043356	CD40 molecule, TNF receptor superfamily member 5.	Uncharacterized protein.	0.466
LOC100301586	ptprc	ENSORLP00000033631	ENSORLP00000035490	CD40 molecule, TNF receptor superfamily member 5.	Protein tyrosine phosphatase receptor type C.	0.467
LOC100301586	tnfsf13b	ENSORLP00000033631	ENSORLP00000022500	CD40 molecule, TNF receptor superfamily member 5.	TNF superfamily member 13b; Belongs to the tumor necrosis factor family.	0.708
LOC101154797	LOC101169209	ENSORLP00000006063	ENSORLP00000036862	Solute carrier family 7 member 1a.	Uncharacterized protein.	0.426
LOC101160820	ptprc	ENSORLP00000030164	ENSORLP00000035490	SCY domain-containing protein.	Protein tyrosine phosphatase receptor type C.	0.445
LOC101164896	ptprc	ENSORLP00000016810	ENSORLP00000035490	Uncharacterized protein.	Protein tyrosine phosphatase receptor type C.	0.401
LOC101164896	sash3	ENSORLP00000016810	ENSORLP00000001552	Uncharacterized protein.	SAM and SH3 domain containing 3.	0.433
LOC101167049	H2M2N2_ORYLA	ENSORLP00000002171	ENSORLP00000012678	CD40 ligand; Belongs to the tumor necrosis factor family.	Uncharacterized protein.	0.429
LOC101167049	LOC100301586	ENSORLP00000002171	ENSORLP00000033631	CD40 ligand; Belongs to the tumor necrosis factor family.	CD40 molecule, TNF receptor superfamily member 5.	0.980
LOC101167049	LOC101169209	ENSORLP00000002171	ENSORLP00000036862	CD40 ligand; Belongs to the tumor necrosis factor family.	Uncharacterized protein.	0.572
LOC101167049	LOC101173752	ENSORLP00000002171	ENSORLP00000022838	CD40 ligand; Belongs to the tumor necrosis factor family.	IGv domain-containing protein.	0.689
LOC101167049	cd276	ENSORLP00000002171	ENSORLP00000042531	CD40 ligand; Belongs to the tumor necrosis factor family.	CD276 molecule.	0.560