STRINGSTRING
ENSORLP00000045928 ENSORLP00000045928 klhl3 klhl3 kmo kmo Fgf1 Fgf1 LOC101156223 LOC101156223 LOC101173693 LOC101173693 H2LDU0_ORYLA H2LDU0_ORYLA LOC101175097 LOC101175097 ILK ILK LOC101171352 LOC101171352 LOC101172012 LOC101172012 SMAD4 SMAD4 LOC101162949 LOC101162949 pax5 pax5 kank2 kank2 LOC101161650 LOC101161650 nphs1 nphs1 ednra ednra gdnf gdnf LOC101166708 LOC101166708 LOC101155532 LOC101155532 LOC101158877 LOC101158877 LOC101158778 LOC101158778 myo1c myo1c LOC101156111 LOC101156111 ednr ednr shh shh osr1 osr1 LOC101158386 LOC101158386 lzts2 lzts2 greb1 greb1 LOC101159590 LOC101159590 wt1 wt1 sim1 sim1 bmp4 bmp4 LOC101165149 LOC101165149 irx3 irx3 efhc2 efhc2 LOC101162832 LOC101162832 me-t me-t LOC101155782 LOC101155782 smo smo TBX2 TBX2 LOC101166490 LOC101166490 magi2 magi2 aqp1 aqp1 LOC100049225 LOC100049225 prkci prkci wnt6 wnt6 LOC101170824 LOC101170824 nup160 nup160 pkd1 pkd1 pdgfb pdgfb LOC101162607 LOC101162607 LOC101170357 LOC101170357 LOC101167695 LOC101167695 LOC101173916 LOC101173916 LOC101168414 LOC101168414 ahi1 ahi1 pkd2 pkd2 tcf21 tcf21 nup85 nup85 MAFB MAFB ENSORLP00000033940 ENSORLP00000033940 sim2 sim2 klhl2 klhl2 LOC101173221 LOC101173221 sulf1 sulf1 itga3 itga3 pax2 pax2 LOC101169804 LOC101169804 wt1-2 wt1-2 basp1 basp1 plce1 plce1 LOC105355370 LOC105355370 LOC101163346 LOC101163346 pax8 pax8 LOC101158315 LOC101158315 LOC101155219 LOC101155219 lhx1 lhx1 enpep enpep hs2st1 hs2st1 LOC101165777 LOC101165777 LOC111948431 LOC111948431 LOC101172686 LOC101172686 LOC101163504 LOC101163504
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSORLP00000045928Catenin, beta interacting protein 1. (83 aa)
klhl3Kelch-like family member 3. (604 aa)
kmoKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (505 aa)
Fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (159 aa)
LOC101156223Si:dkey-237i9.8. (782 aa)
LOC101173693Heparan sulfate 2-O-sulfotransferase 1b. (357 aa)
H2LDU0_ORYLAPaired domain-containing protein. (140 aa)
LOC101175097Dachsous cadherin-related 1a. (3158 aa)
ILKIntegrin linked kinase. (452 aa)
LOC101171352Dachsous cadherin-related 1b. (3281 aa)
LOC101172012Uncharacterized protein. (452 aa)
SMAD4Mothers against decapentaplegic homolog. (510 aa)
LOC101162949Iroquois homeobox 1a. (500 aa)
pax5Paired box 5. (396 aa)
kank2KN motif and ankyrin repeat domains 2. (1001 aa)
LOC101161650Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (157 aa)
nphs1NPHS1 adhesion molecule, nephrin. (1180 aa)
ednraEndothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (439 aa)
gdnfGlial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (265 aa)
LOC101166708NPHS2 stomatin family member, podocin. (356 aa)
LOC101155532Coenzyme Q8B. (638 aa)
LOC101158877Myosin Ic, paralog a; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1045 aa)
LOC101158778COMM domain containing 5. (211 aa)
myo1cMyosin Ic, paralog b; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1024 aa)
LOC101156111T-box transcription factor 2a. (561 aa)
ednrG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (413 aa)
shhHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (414 aa)
osr1Odd-skipped related transcription factor 1. (269 aa)
LOC101158386Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family. (419 aa)
lzts2Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family. (709 aa)
greb1Growth regulating estrogen receptor binding 1. (1927 aa)
LOC101159590Platelet/endothelial cell adhesion molecule 1. (793 aa)
wt1Uncharacterized protein. (435 aa)
sim1SIM bHLH transcription factor 1. (759 aa)
bmp4Bone morphogenetic protein 4. (441 aa)
LOC101165149Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (510 aa)
irx3Iroquois homeobox 3a. (423 aa)
efhc2EF-hand domain (C-terminal) containing 2. (734 aa)
LOC101162832Extracellular sulfatase. (885 aa)
me-tMe-Tam. (419 aa)
LOC101155782Iroquois homeobox 1b. (452 aa)
smoSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (828 aa)
TBX2T-box transcription factor 2. (682 aa)
LOC101166490Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (271 aa)
magi2Membrane associated guanylate kinase, WW and PDZ domain containing 2a. (1331 aa)
aqp1Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (261 aa)
LOC100049225Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family. (427 aa)
prkciProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (554 aa)
wnt6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
LOC101170824Uncharacterized protein. (867 aa)
nup160Nucleoporin 160. (1397 aa)
pkd1Uncharacterized protein. (4114 aa)
pdgfbPlatelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (553 aa)
LOC101162607Leucine zipper, putative tumor suppressor family member 3b. (1091 aa)
LOC101170357Thrombospondin, type I, domain containing 7Aa. (1791 aa)
LOC101167695Transmembrane protein 59-like. (338 aa)
LOC101173916Mothers against decapentaplegic homolog. (538 aa)
LOC101168414Empty spiracles homeobox 1. (233 aa)
ahi1Abelson helper integration site 1. (854 aa)
pkd2Polycystin-2; Component of a heteromeric calcium-permeable ion channel formed by PKD1 and PKD2 that is activated by interaction between PKD1 and a Wnt family member, such as WNT3A and WNT9B. Can also form a functional, homotetrameric ion channel (By similarity). Functions as non-selective, voltage-gated cation channel. Required for normal oscillation of Ca(2+) levels within cilia; these oscillations of the intraciliary Ca(2+) levels can trigger cytoplasmic Ca(2+) signaling cascades (By similarity). May contribute to the release of Ca(2+) stores from the endoplasmic reticulum (By simila [...] (946 aa)
tcf21Transcription factor 21. (171 aa)
nup85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (652 aa)
MAFBMAF bZIP transcription factor B. (434 aa)
ENSORLP00000033940CA domain-containing protein. (236 aa)
sim2Uncharacterized protein. (683 aa)
klhl2Kelch-like family member 2. (605 aa)
LOC101173221Membrane associated guanylate kinase, WW and PDZ domain containing 2b. (1528 aa)
sulf1Sulfatase 1. (1151 aa)
itga3Integrin, alpha 3b; Belongs to the integrin alpha chain family. (1075 aa)
pax2Paired box 2b. (387 aa)
LOC101169804Epithelial cell adhesion molecule. (386 aa)
wt1-2Uncharacterized protein. (418 aa)
basp1Brain abundant, membrane attached signal protein 1. (208 aa)
plce1Phospholipase C, epsilon 1. (2269 aa)
LOC105355370Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (271 aa)
LOC101163346Bone morphogenetic protein 16. (516 aa)
pax8Paired box 8. (444 aa)
LOC101158315TYRO3 protein tyrosine kinase. (839 aa)
LOC101155219Paired domain-containing protein. (485 aa)
lhx1LIM homeobox 1a. (406 aa)
enpepAminopeptidase. (963 aa)
hs2st1Heparan sulfate 2-O-sulfotransferase 1a. (357 aa)
LOC101165777Podocalyxin-like. (419 aa)
LOC111948431TH1 domain-containing protein. (298 aa)
LOC101172686Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (445 aa)
LOC101163504Mothers against decapentaplegic homolog. (528 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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