(61 nodes) Postsynapse organization network (Oryzias latipes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	lgmn	Legumain. (434 aa)
	H2L2U9_ORYLA	SH3 and multiple ankyrin repeat domains 2a. (1494 aa)
	prmt3	Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (524 aa)
	SHISA6	Shisa family member 6. (624 aa)
	HOMER1	Homer scaffold protein 1. (376 aa)
	LOC101165159	Netrin G2. (530 aa)
	H2LIM0_ORYLA	Uncharacterized protein. (726 aa)
	LOC101171843	Uncharacterized protein. (469 aa)
	LOC101172489	ADAM metallopeptidase domain 10b. (784 aa)
	LOC101164658	Uncharacterized protein. (242 aa)
	Nlgn3	Neuroligin 3a. (851 aa)
	LOC101159214	Discs, large homolog 4a (Drosophila); Belongs to the MAGUK family. (800 aa)
	dock10	Dedicator of cytokinesis 10; Belongs to the DOCK family. (1989 aa)
	colq	Collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase. (454 aa)
	LOC101167744	Uncharacterized protein. (2049 aa)
	adam10	Uncharacterized protein. (747 aa)
	LOC101163175	Homer scaffold protein 1b. (359 aa)
	LOC101168921	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (410 aa)
	fnta	Farnesyltransferase, CAAX box, alpha. (387 aa)
	LOC101156607	Nitric oxide synthase 1 (neuronal) adaptor protein b. (500 aa)
	dbnl	Drebrin-like b. (390 aa)
	CDC42	Cell division cycle 42. (191 aa)
	zdhhc12	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (270 aa)
	LOC101161673	Apolipoprotein Eb. (265 aa)
	nlgn1	Neuroligin 1. (779 aa)
	LOC101154926	Glycine receptor, beta a; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (498 aa)
	LOC101168332	COesterase domain-containing protein. (794 aa)
	LOC101169951	Uncharacterized protein. (330 aa)
	LOC101173070	Uncharacterized protein. (369 aa)
	LOC101155523	Uncharacterized protein. (375 aa)
	LOC101157545	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (264 aa)
	dbn1	Drebrin 1. (602 aa)
	GLRB	Glycine receptor beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (518 aa)
	ephb3	Receptor protein-tyrosine kinase. (1013 aa)
	ENSORLP00000026279	Laminin N-terminal domain-containing protein. (367 aa)
	LOC101174454	Uncharacterized protein. (191 aa)
	nlgn2	COesterase domain-containing protein. (859 aa)
	LOC101172375	Uncharacterized protein. (1694 aa)
	nlgn3b	Neuroligin 3b. (819 aa)
	LOC101164400	Uncharacterized protein. (191 aa)
	ENSORLP00000034659	Reelin domain-containing protein. (259 aa)
	ENSORLP00000035838	FERM_f0 domain-containing protein. (122 aa)
	LOC101157471	Si:dkey-34e4.1. (648 aa)
	LOC101156731	Zgc:92107. (1136 aa)
	itga3	Integrin, alpha 3b; Belongs to the integrin alpha chain family. (1075 aa)
	LOC101163480	PID domain-containing protein. (752 aa)
	nlgn2-2	Neuroligin 2a. (828 aa)
	tanc1	Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1b. (1912 aa)
	LOC101166140	Si:dkey-40c11.2. (750 aa)
	shank3	SH3 and multiple ankyrin repeat domains 3a. (1971 aa)
	LOC101159448	Shisa family member 7. (668 aa)
	LOC101156053	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (779 aa)
	LOC101155777	Uncharacterized protein. (372 aa)
	gphn	Gephyrin b. (794 aa)
	LOC101165761	Eph receptor B3a. (926 aa)
	Tmem108	Uncharacterized protein. (346 aa)
	LOC101165307	SH3 and multiple ankyrin repeat domains 1. (2440 aa)
	tmem108	Uncharacterized protein. (99 aa)
	LOC101166399	Apolipoprotein Ea. (262 aa)
	arhgap39	Rho GTPase activating protein 39. (1000 aa)
	pick1	Protein interacting with prkca 1. (421 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	ENSORLP00000035838	ENSORLP00000015084	ENSORLP00000035838	Cell division cycle 42.	FERM_f0 domain-containing protein.	0.468
CDC42	LOC101156731	ENSORLP00000015084	ENSORLP00000036642	Cell division cycle 42.	Zgc:92107.	0.442
CDC42	LOC101165307	ENSORLP00000015084	ENSORLP00000045035	Cell division cycle 42.	SH3 and multiple ankyrin repeat domains 1.	0.403
CDC42	LOC101167744	ENSORLP00000015084	ENSORLP00000009960	Cell division cycle 42.	Uncharacterized protein.	0.403
CDC42	LOC101172375	ENSORLP00000015084	ENSORLP00000033665	Cell division cycle 42.	Uncharacterized protein.	0.403
CDC42	arhgap39	ENSORLP00000015084	ENSORLP00000045711	Cell division cycle 42.	Rho GTPase activating protein 39.	0.442
CDC42	dock10	ENSORLP00000015084	ENSORLP00000009215	Cell division cycle 42.	Dedicator of cytokinesis 10; Belongs to the DOCK family.	0.893
CDC42	shank3	ENSORLP00000015084	ENSORLP00000041483	Cell division cycle 42.	SH3 and multiple ankyrin repeat domains 3a.	0.403
ENSORLP00000026279	LOC101165159	ENSORLP00000026279	ENSORLP00000005182	Laminin N-terminal domain-containing protein.	Netrin G2.	0.545
ENSORLP00000034659	H2LIM0_ORYLA	ENSORLP00000034659	ENSORLP00000005849	Reelin domain-containing protein.	Uncharacterized protein.	0.944
ENSORLP00000035838	CDC42	ENSORLP00000035838	ENSORLP00000015084	FERM_f0 domain-containing protein.	Cell division cycle 42.	0.468
ENSORLP00000035838	H2L2U9_ORYLA	ENSORLP00000035838	ENSORLP00000000049	FERM_f0 domain-containing protein.	SH3 and multiple ankyrin repeat domains 2a.	0.902
ENSORLP00000035838	HOMER1	ENSORLP00000035838	ENSORLP00000003073	FERM_f0 domain-containing protein.	Homer scaffold protein 1.	0.528
ENSORLP00000035838	LOC101159214	ENSORLP00000035838	ENSORLP00000008601	FERM_f0 domain-containing protein.	Discs, large homolog 4a (Drosophila); Belongs to the MAGUK family.	0.625
ENSORLP00000035838	LOC101163175	ENSORLP00000035838	ENSORLP00000011340	FERM_f0 domain-containing protein.	Homer scaffold protein 1b.	0.528
ENSORLP00000035838	LOC101164400	ENSORLP00000035838	ENSORLP00000034529	FERM_f0 domain-containing protein.	Uncharacterized protein.	0.468
ENSORLP00000035838	LOC101164658	ENSORLP00000035838	ENSORLP00000007959	FERM_f0 domain-containing protein.	Uncharacterized protein.	0.447
ENSORLP00000035838	LOC101168332	ENSORLP00000035838	ENSORLP00000020294	FERM_f0 domain-containing protein.	COesterase domain-containing protein.	0.451
ENSORLP00000035838	LOC101174454	ENSORLP00000035838	ENSORLP00000028896	FERM_f0 domain-containing protein.	Uncharacterized protein.	0.447
ENSORLP00000035838	Nlgn3	ENSORLP00000035838	ENSORLP00000008112	FERM_f0 domain-containing protein.	Neuroligin 3a.	0.451