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tsen54 tsen54 LOC101167527 LOC101167527 Pop7 Pop7 clp1 clp1 LOC101158762 LOC101158762 trmt10c trmt10c tarbp2 tarbp2 dhx9 dhx9 rpp38 rpp38 LOC101167465 LOC101167465 dicer1 dicer1 H2MDZ5_ORYLA H2MDZ5_ORYLA pop5 pop5 H2MJZ4_ORYLA H2MJZ4_ORYLA H2MR55_ORYLA H2MR55_ORYLA prkra prkra prorp prorp pop4 pop4 rpp30 rpp30 rpp40 rpp40 tsen2 tsen2 drosha drosha hsd17b10 hsd17b10 pop1 pop1 tsnax tsnax
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
tsen54TSEN54 tRNA splicing endonuclease subunit. (493 aa)
LOC101167527Ribonuclease P 21 subunit. (146 aa)
Pop7Ribonuclease P protein subunit p20; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences. (139 aa)
clp1Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (441 aa)
LOC101158762Alba domain-containing protein. (187 aa)
trmt10ctRNA methyltransferase 10C, mitochondrial RNase P subunit. (506 aa)
tarbp2RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...] (345 aa)
dhx9DEAH (Asp-Glu-Ala-His) box helicase 9. (1283 aa)
rpp38Ribonuclease P/MRP 38 subunit. (275 aa)
LOC101167465Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. (947 aa)
dicer1Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily. (1888 aa)
H2MDZ5_ORYLARibonuclease P and MRP subunit p25, b. (217 aa)
pop5Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (166 aa)
H2MJZ4_ORYLADGCR8 microprocessor complex subunit. (769 aa)
H2MR55_ORYLARibonuclease P/MRP 25 subunit-like. (184 aa)
prkraProtein kinase, interferon-inducible double stranded RNA dependent activator. (307 aa)
prorpProtein only RNase P catalytic subunit. (601 aa)
pop4Ribonuclease P protein subunit p29; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. (221 aa)
rpp30Ribonuclease P/MRP 30 subunit. (289 aa)
rpp40Uncharacterized protein. (379 aa)
tsen2tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...] (401 aa)
droshaDrosha ribonuclease III. (1317 aa)
hsd17b10Hydroxysteroid (17-beta) dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (260 aa)
pop1POP1 homolog, ribonuclease P/MRP subunit. (953 aa)
tsnaxTranslin-associated factor X. (282 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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