(25 nodes) Regulation of leukocyte apoptotic process network (Oryzias latipes)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AXL	AXL receptor tyrosine kinase. (939 aa)
	gas6	Growth arrest-specific 6. (684 aa)
	noc2l	NOC2-like nucleolar associated transcriptional repressor. (745 aa)
	LOC101174272-2	PRELI domain containing 1a. (210 aa)
	LOC101168078	Receptor-interacting serine-threonine kinase 3; Belongs to the protein kinase superfamily. (481 aa)
	LOC101161201	Galectin. (373 aa)
	slc46a2	Solute carrier family 46 member 2. (446 aa)
	sirt1	Deacetylase sirtuin-type domain-containing protein. (680 aa)
	kifap3	Kinesin-associated protein 3b. (773 aa)
	H2MJT0_ORYLA	Uncharacterized protein. (589 aa)
	il10	Interleukin 10. (181 aa)
	Nf1	Uncharacterized protein. (506 aa)
	gpam	Glycerol-3-phosphate acyltransferase 1, mitochondrial. (823 aa)
	LOC101159552	Galectin. (314 aa)
	efna1	Ephrin-A1b; Belongs to the ephrin family. (263 aa)
	rapgef2	Rap guanine nucleotide exchange factor (GEF) 2. (1630 aa)
	LOC101168038	Protein kinase domain-containing protein. (509 aa)
	LOC101168285	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (415 aa)
	LOC101160820	SCY domain-containing protein. (131 aa)
	ENSORLP00000030535	Fibronectin type-III domain-containing protein. (383 aa)
	LOC101164954	PRELI/MSF1 domain-containing protein. (221 aa)
	LOC111948169	Ephrin-A1a; Belongs to the ephrin family. (222 aa)
	fadd	Uncharacterized protein. (192 aa)
	fnip1	Folliculin interacting protein 1. (1246 aa)
	aurkb	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (332 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AXL	gas6	ENSORLP00000001378	ENSORLP00000005987	AXL receptor tyrosine kinase.	Growth arrest-specific 6.	0.807
AXL	il10	ENSORLP00000001378	ENSORLP00000019691	AXL receptor tyrosine kinase.	Interleukin 10.	0.415
ENSORLP00000030535	il10	ENSORLP00000030535	ENSORLP00000019691	Fibronectin type-III domain-containing protein.	Interleukin 10.	0.449
H2MJT0_ORYLA	Nf1	ENSORLP00000018929	ENSORLP00000026133	Uncharacterized protein.	Uncharacterized protein.	0.943
H2MJT0_ORYLA	aurkb	ENSORLP00000018929	ENSORLP00000000711	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.489
LOC101159552	il10	ENSORLP00000028015	ENSORLP00000019691	Galectin.	Interleukin 10.	0.489
LOC101160820	il10	ENSORLP00000030164	ENSORLP00000019691	SCY domain-containing protein.	Interleukin 10.	0.420
LOC101161201	il10	ENSORLP00000011528	ENSORLP00000019691	Galectin.	Interleukin 10.	0.489
LOC101168038	fadd	ENSORLP00000029474	ENSORLP00000043356	Protein kinase domain-containing protein.	Uncharacterized protein.	0.930
LOC101168078	fadd	ENSORLP00000011349	ENSORLP00000043356	Receptor-interacting serine-threonine kinase 3; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.947
LOC101168285	fadd	ENSORLP00000029843	ENSORLP00000043356	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.930
Nf1	H2MJT0_ORYLA	ENSORLP00000026133	ENSORLP00000018929	Uncharacterized protein.	Uncharacterized protein.	0.943
Nf1	aurkb	ENSORLP00000026133	ENSORLP00000000711	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.489
aurkb	H2MJT0_ORYLA	ENSORLP00000000711	ENSORLP00000018929	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.489
aurkb	Nf1	ENSORLP00000000711	ENSORLP00000026133	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.489
aurkb	noc2l	ENSORLP00000000711	ENSORLP00000007000	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	NOC2-like nucleolar associated transcriptional repressor.	0.652
fadd	LOC101168038	ENSORLP00000043356	ENSORLP00000029474	Uncharacterized protein.	Protein kinase domain-containing protein.	0.930
fadd	LOC101168078	ENSORLP00000043356	ENSORLP00000011349	Uncharacterized protein.	Receptor-interacting serine-threonine kinase 3; Belongs to the protein kinase superfamily.	0.947
fadd	LOC101168285	ENSORLP00000043356	ENSORLP00000029843	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.930
fnip1	sirt1	ENSORLP00000044929	ENSORLP00000017142	Folliculin interacting protein 1.	Deacetylase sirtuin-type domain-containing protein.	0.477