(37 nodes) Lateral plasma membrane network (Oryzias latipes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H2L7K0_ORYLA	Thyroglobulin type-1 domain-containing protein. (232 aa)
	H2LCK7_ORYLA	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (201 aa)
	mtcl1	Microtubule crosslinking factor 1. (1899 aa)
	RNF126	Ring finger protein 126. (474 aa)
	LOC101161541	Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family. (695 aa)
	pcsk6	Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (923 aa)
	atp2b2	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1257 aa)
	akap7	Uncharacterized protein. (501 aa)
	actn3	Actinin alpha 3b. (898 aa)
	atp2b3	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1189 aa)
	pcsk5	Proprotein convertase subtilisin/kexin type 5b; Belongs to the peptidase S8 family. (1878 aa)
	fam168b	Family with sequence similarity 168 member B. (199 aa)
	bves	Blood vessel epicardial substance. (356 aa)
	actn1	Actinin, alpha 1. (918 aa)
	LOC105357584	Uncharacterized protein. (904 aa)
	ENSORLP00000033296	Claudin b. (205 aa)
	ENSORLP00000043772	TNFR-Cys domain-containing protein. (288 aa)
	anxa2	Annexin. (359 aa)
	arl2	ADP-ribosylation factor-like 2; Belongs to the small GTPase superfamily. Arf family. (184 aa)
	LOC101172706	Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (2240 aa)
	c1qtnf5	C1q and TNF related 5. (283 aa)
	lepr	Leptin recepter. (1074 aa)
	LOC101167451	Annexin. (336 aa)
	ENSORLP00000039963	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (174 aa)
	mfsd3	Major facilitator superfamily domain containing 3. (421 aa)
	atp2b1	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1250 aa)
	LOC101166715	Uncharacterized protein; Belongs to the potassium channel family. (719 aa)
	H2LJC9_ORYLA	Proprotein convertase subtilisin/kexin type 5a. (1036 aa)
	LOC101164086	Actinin, alpha 2b. (895 aa)
	tbcd	Tubulin folding cofactor D. (1195 aa)
	LOC101156250	Major intrinsic protein of lens fiber b; Belongs to the MIP/aquaporin (TC 1.A.8) family. (263 aa)
	anxa1	Annexin. (337 aa)
	LOC101161495	Annexin. (347 aa)
	LOC101161368	Major intrinsic protein of lens fiber a; Belongs to the MIP/aquaporin (TC 1.A.8) family. (263 aa)
	kcnb1	Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (793 aa)
	LOC101155449	Uncharacterized protein. (920 aa)
	H2L737_ORYLA	Uncharacterized protein. (151 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSORLP00000033296	H2L737_ORYLA	ENSORLP00000033296	ENSORLP00000001645	Claudin b.	Uncharacterized protein.	0.660
ENSORLP00000033296	H2LCK7_ORYLA	ENSORLP00000033296	ENSORLP00000003646	Claudin b.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.659
H2L737_ORYLA	ENSORLP00000033296	ENSORLP00000001645	ENSORLP00000033296	Uncharacterized protein.	Claudin b.	0.660
H2L737_ORYLA	H2LCK7_ORYLA	ENSORLP00000001645	ENSORLP00000003646	Uncharacterized protein.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.658
H2LCK7_ORYLA	ENSORLP00000033296	ENSORLP00000003646	ENSORLP00000033296	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin b.	0.659
H2LCK7_ORYLA	H2L737_ORYLA	ENSORLP00000003646	ENSORLP00000001645	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Uncharacterized protein.	0.658
LOC101155449	actn1	ENSORLP00000001152	ENSORLP00000032375	Uncharacterized protein.	Actinin, alpha 1.	0.901
LOC101161541	LOC101166715	ENSORLP00000043809	ENSORLP00000034183	Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family.	Uncharacterized protein; Belongs to the potassium channel family.	0.903
LOC101166715	LOC101161541	ENSORLP00000034183	ENSORLP00000043809	Uncharacterized protein; Belongs to the potassium channel family.	Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family.	0.903
LOC101167451	anxa2	ENSORLP00000040227	ENSORLP00000043022	Annexin.	Annexin.	0.902
actn1	LOC101155449	ENSORLP00000032375	ENSORLP00000001152	Actinin, alpha 1.	Uncharacterized protein.	0.901
anxa2	LOC101167451	ENSORLP00000043022	ENSORLP00000040227	Annexin.	Annexin.	0.902
arl2	tbcd	ENSORLP00000042357	ENSORLP00000009108	ADP-ribosylation factor-like 2; Belongs to the small GTPase superfamily. Arf family.	Tubulin folding cofactor D.	0.957
tbcd	arl2	ENSORLP00000009108	ENSORLP00000042357	Tubulin folding cofactor D.	ADP-ribosylation factor-like 2; Belongs to the small GTPase superfamily. Arf family.	0.957