(68 nodes) Perinuclear region of cytoplasm network (Oryzias latipes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	nrde2	NRDE-2, necessary for RNA interference, domain containing. (1090 aa)
	LOC101167075	Apolipoprotein Da, duplicate 1; Belongs to the calycin superfamily. Lipocalin family. (186 aa)
	pikfyve	Phosphoinositide kinase, FYVE finger containing. (2070 aa)
	LOC101175224	Si:dkey-43k4.5; Belongs to the potassium channel family. (525 aa)
	osbpl6	Oxysterol-binding protein; Belongs to the OSBP family. (919 aa)
	wdr44	WD repeat domain 44. (909 aa)
	bspry	Uncharacterized protein. (463 aa)
	prkacb	Uncharacterized protein; Belongs to the protein kinase superfamily. (380 aa)
	ENSORLP00000027094	Lymphocyte antigen 6 family member pge. (125 aa)
	ofcc1	Uncharacterized protein. (1090 aa)
	aanat	N-acetyltransferase domain-containing protein. (216 aa)
	SRC	Tyrosine-protein kinase. (544 aa)
	ENSORLP00000028595	Uncharacterized protein. (183 aa)
	LOC101163234	Fork-head domain-containing protein. (331 aa)
	LOC101174986	Cryptochrome circadian regulator 5. (521 aa)
	LOC101170718	Apolipoprotein Db; Belongs to the calycin superfamily. Lipocalin family. (232 aa)
	epo	Erythropoietin; Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Belongs to the EPO/TPO family. (185 aa)
	aanat2	Arylalkylamine N-acetyltransferase 2. (208 aa)
	dhx58	DEXH (Asp-Glu-X-His) box polypeptide 58. (731 aa)
	MTDH	Uncharacterized protein. (537 aa)
	LOC101160693	Ran GTPase activating protein 1b. (564 aa)
	anp32a	Acidic (leucine-rich) nuclear phosphoprotein 32 family, member A. (257 aa)
	rangap1	RAN GTPase activating protein 1a. (554 aa)
	mogat2	Monoacylglycerol O-acyltransferase 2. (335 aa)
	rundc1	RUN domain containing 1. (563 aa)
	LOC101166541	Oxysterol-binding protein; Belongs to the OSBP family. (921 aa)
	ENSORLP00000037656	Uncharacterized protein. (112 aa)
	gak	Cyclin G associated kinase. (1301 aa)
	hif1an	Hypoxia inducible factor 1 subunit alpha inhibitor. (359 aa)
	LOC101164480	Tyrosine-protein kinase. (551 aa)
	ENSORLP00000036222	ANK_REP_REGION domain-containing protein. (378 aa)
	myc	BHLH domain-containing protein. (527 aa)
	dcun1d3	DCN1-like protein. (325 aa)
	LOC101175572	Oxysterol-binding protein; Belongs to the OSBP family. (739 aa)
	creb3l2	cAMP responsive element binding protein 3-like 2. (544 aa)
	LOC101173221	Membrane associated guanylate kinase, WW and PDZ domain containing 2b. (1528 aa)
	sirt2	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (378 aa)
	LOC101163742	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (377 aa)
	dnajc6	DnaJ (Hsp40) homolog, subfamily C, member 6. (899 aa)
	wbp2nl	WBP2 N-terminal like. (302 aa)
	LOC101170232	Apolipoprotein Db; Belongs to the calycin superfamily. Lipocalin family. (195 aa)
	pclaf	PCNA clamp associated factor. (117 aa)
	LOC101160964	Uncharacterized protein; Belongs to the protein kinase superfamily. (359 aa)
	LOC101157618	Uncharacterized protein. (298 aa)
	magi2	Membrane associated guanylate kinase, WW and PDZ domain containing 2a. (1331 aa)
	fbxl5	F-box and leucine-rich repeat protein 5. (692 aa)
	atraid	All-trans retinoic acid-induced differentiation factor. (234 aa)
	LOC101170773	Oxysterol-binding protein; Belongs to the OSBP family. (754 aa)
	LOC101166733	Monoacylglycerol O-acyltransferase 3b. (327 aa)
	LOC101161217	Oxysterol-binding protein; Belongs to the OSBP family. (776 aa)
	cd34	Uncharacterized protein. (328 aa)
	LOC101155887	Oxysterol-binding protein; Belongs to the OSBP family. (784 aa)
	LOC101170876	Uncharacterized protein; Belongs to the protein kinase superfamily. (354 aa)
	LOC101169578	Nuclear receptor binding protein 1. (582 aa)
	tmem134	Transmembrane protein 134. (190 aa)
	osbpl7	Oxysterol-binding protein; Belongs to the OSBP family. (820 aa)
	LOC101170578	Protein kinase domain-containing protein. (524 aa)
	hmgcll1	3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1. (310 aa)
	myd88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (288 aa)
	cib1	Calcium and integrin binding 1 (calmyrin). (189 aa)
	nanos1a	NANOS1A; Belongs to the nanos family. (184 aa)
	LOC101163258	Oxysterol-binding protein; Belongs to the OSBP family. (811 aa)
	LOC101169804	Epithelial cell adhesion molecule. (386 aa)
	aanat1b	Arylalkylamine N-acetyltransferase 1b. (226 aa)
	osbpl3	Oxysterol-binding protein; Belongs to the OSBP family. (880 aa)
	akap12	A kinase (PRKA) anchor protein 12b. (1419 aa)
	OSBPL1A	Oxysterol-binding protein; Belongs to the OSBP family. (435 aa)
	LOC101160562	Oxysterol-binding protein; Belongs to the OSBP family. (887 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSORLP00000036222	OSBPL1A	ENSORLP00000036222	ENSORLP00000021176	ANK_REP_REGION domain-containing protein.	Oxysterol-binding protein; Belongs to the OSBP family.	0.875
LOC101157618	cd34	ENSORLP00000019824	ENSORLP00000009548	Uncharacterized protein.	Uncharacterized protein.	0.900
LOC101160693	rangap1	ENSORLP00000003170	ENSORLP00000017656	Ran GTPase activating protein 1b.	RAN GTPase activating protein 1a.	0.902
LOC101160964	LOC101163742	ENSORLP00000018527	ENSORLP00000033579	Uncharacterized protein; Belongs to the protein kinase superfamily.	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.	0.900
LOC101160964	LOC101170876	ENSORLP00000018527	ENSORLP00000045423	Uncharacterized protein; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.900
LOC101160964	creb3l2	ENSORLP00000018527	ENSORLP00000035587	Uncharacterized protein; Belongs to the protein kinase superfamily.	cAMP responsive element binding protein 3-like 2.	0.650
LOC101160964	prkacb	ENSORLP00000018527	ENSORLP00000026566	Uncharacterized protein; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.901
LOC101163742	LOC101160964	ENSORLP00000033579	ENSORLP00000018527	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.900
LOC101163742	LOC101170876	ENSORLP00000033579	ENSORLP00000045423	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.900
LOC101163742	creb3l2	ENSORLP00000033579	ENSORLP00000035587	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.	cAMP responsive element binding protein 3-like 2.	0.650
LOC101163742	prkacb	ENSORLP00000033579	ENSORLP00000026566	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.901
LOC101164480	SRC	ENSORLP00000036233	ENSORLP00000008431	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.900
LOC101166733	mogat2	ENSORLP00000010150	ENSORLP00000015768	Monoacylglycerol O-acyltransferase 3b.	Monoacylglycerol O-acyltransferase 2.	0.903
LOC101170876	LOC101160964	ENSORLP00000045423	ENSORLP00000018527	Uncharacterized protein; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.900
LOC101170876	LOC101163742	ENSORLP00000045423	ENSORLP00000033579	Uncharacterized protein; Belongs to the protein kinase superfamily.	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.	0.900
LOC101170876	creb3l2	ENSORLP00000045423	ENSORLP00000035587	Uncharacterized protein; Belongs to the protein kinase superfamily.	cAMP responsive element binding protein 3-like 2.	0.650
LOC101170876	prkacb	ENSORLP00000045423	ENSORLP00000026566	Uncharacterized protein; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.900
OSBPL1A	ENSORLP00000036222	ENSORLP00000021176	ENSORLP00000036222	Oxysterol-binding protein; Belongs to the OSBP family.	ANK_REP_REGION domain-containing protein.	0.875
SRC	LOC101164480	ENSORLP00000008431	ENSORLP00000036233	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.900
aanat	aanat1b	ENSORLP00000028585	ENSORLP00000038230	N-acetyltransferase domain-containing protein.	Arylalkylamine N-acetyltransferase 1b.	0.902