STRINGSTRING
cenpk cenpk kdm1a kdm1a bod1l1 bod1l1 ENSORLP00000032040 ENSORLP00000032040 LOC101168459 LOC101168459 cbx5 cbx5 LOC100049459 LOC100049459 terb2 terb2 dhx36 dhx36 LOC101159715 LOC101159715 znf827 znf827 recql4 recql4 nek2 nek2 sgo1 sgo1 cenpv cenpv rnf8 rnf8 LOC101155740 LOC101155740 LOC101162023 LOC101162023 cenph cenph terf2ip terf2ip LOC101172197 LOC101172197 LOC101172596 LOC101172596 Rif1 Rif1 ttk ttk LOC101161711 LOC101161711 ska1 ska1 H2M904_ORYLA H2M904_ORYLA LOC105355769 LOC105355769 terf2 terf2 cdt1 cdt1 cenpw cenpw terf1 terf1 stn1 stn1 cenpo cenpo terb1 terb1 ENSORLP00000035938 ENSORLP00000035938 CBX1-2 CBX1-2 bub1b bub1b cenpf cenpf LOC101161713 LOC101161713 rcc2 rcc2 LOC101165555 LOC101165555 zwilch zwilch LOC101173508 LOC101173508 LOC101172442 LOC101172442 LOC101169070 LOC101169070 gpatch11 gpatch11 Knl1 Knl1 fbxo28 fbxo28 LOC101163116 LOC101163116 LOC105356504 LOC105356504 ska2 ska2 spdl1 spdl1 mis12 mis12 dna2 dna2 nuf2 nuf2 cenpn cenpn LOC101171430 LOC101171430 anapc16 anapc16 fam43a fam43a LOC101159942 LOC101159942 LOC101159673 LOC101159673 dclre1b dclre1b atrx atrx kntc1 kntc1 cenpt cenpt ndc80 ndc80 cenpq cenpq mtbp mtbp cenpl cenpl LOC101156724 LOC101156724 LOC101155061 LOC101155061 LOC101157951 LOC101157951 LOC101155373 LOC101155373 cenpi cenpi LOC101161885 LOC101161885 hells hells ten1 ten1 kmt5b kmt5b H2L4M6_ORYLA H2L4M6_ORYLA pot1 pot1 LOC101155136 LOC101155136 spc25 spc25 CBX1 CBX1 WDSUB1 WDSUB1 fam43b fam43b bub1 bub1 nsl1 nsl1 spc24 spc24 ENSORLP00000033799 ENSORLP00000033799 LOC101160375 LOC101160375 smarca4 smarca4 sirt6 sirt6 ckap5 ckap5 zw10 zw10 LOC101159187 LOC101159187 mettl24 mettl24 LOC101170809 LOC101170809 ska3 ska3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cenpkCentromere protein K. (266 aa)
kdm1aLysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (860 aa)
bod1l1Uncharacterized protein. (1105 aa)
ENSORLP00000032040Uncharacterized protein. (229 aa)
LOC101168459Baculoviral IAP repeat containing 5b. (147 aa)
cbx5Chromobox homolog 5 (HP1 alpha homolog, Drosophila). (203 aa)
LOC100049459Chromobox homolog 3a (HP1 gamma homolog, Drosophila). (174 aa)
terb2Telomere repeat binding bouquet formation protein 2. (212 aa)
dhx36DEAH (Asp-Glu-Ala-His) box polypeptide 36. (1050 aa)
LOC101159715Uncharacterized protein. (986 aa)
znf827Zinc finger protein 827. (1498 aa)
recql4RecQ helicase-like 4. (1546 aa)
nek2NIMA-related kinase 2. (442 aa)
sgo1Shugoshin_C domain-containing protein. (654 aa)
cenpvCentromere protein V. (133 aa)
rnf8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (516 aa)
LOC101155740Calcyon neuron-specific vesicular protein. (184 aa)
LOC101162023Uncharacterized protein. (1660 aa)
cenphCENP-H domain-containing protein. (232 aa)
terf2ipUncharacterized protein. (682 aa)
LOC101172197TERF1 (TRF1)-interacting nuclear factor 2. (566 aa)
LOC101172596Zinc finger protein 618. (919 aa)
Rif1Uncharacterized protein. (1520 aa)
ttkTtk protein kinase. (994 aa)
LOC101161711Zinc finger and BTB domain containing 48. (625 aa)
ska1Spindle and kinetochore associated complex subunit 1. (249 aa)
H2M904_ORYLASi:dkey-76k16.6. (235 aa)
LOC105355769EGF-like domain-containing protein. (520 aa)
terf2HTH myb-type domain-containing protein. (627 aa)
cdt1Chromatin licensing and DNA replication factor 1. (607 aa)
cenpwUncharacterized protein. (75 aa)
terf1Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (454 aa)
stn1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (359 aa)
cenpoCentromere protein O. (269 aa)
terb1Telomere repeat binding bouquet formation protein 1. (704 aa)
ENSORLP00000035938Uncharacterized protein. (521 aa)
CBX1-2Chromobox homolog 1b (HP1 beta homolog Drosophila). (264 aa)
bub1bBUB1 N-terminal domain-containing protein. (564 aa)
cenpfCentromere protein F. (2835 aa)
LOC101161713SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1581 aa)
rcc2Regulator of chromosome condensation 2. (512 aa)
LOC101165555SET domain-containing protein. (1938 aa)
zwilchZwilch kinetochore protein. (607 aa)
LOC101173508Marker of proliferation Ki-67. (1982 aa)
LOC101172442C2H2-type domain-containing protein. (683 aa)
LOC101169070Radial spoke head 10 homolog B. (680 aa)
gpatch11G patch domain containing 11. (258 aa)
Knl1Uncharacterized protein. (1367 aa)
fbxo28F-box protein 28. (367 aa)
LOC101163116Neuregulin 3b. (763 aa)
LOC105356504Cysteine three histidine 1. (297 aa)
ska2SKA2 domain-containing protein. (146 aa)
spdl1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex; Belongs to the Spindly family. (573 aa)
mis12MIS12 kinetochore complex component. (211 aa)
dna2DNA replication helicase/nuclease 2. (1396 aa)
nuf2UF2 component of NDC80 kinetochore complex. (454 aa)
cenpnCentromere protein N. (345 aa)
LOC101171430Uncharacterized protein. (1871 aa)
anapc16Anaphase promoting complex subunit 16. (83 aa)
fam43aFamily with sequence similarity 43 member A. (355 aa)
LOC101159942Chromobox homolog 3b. (193 aa)
LOC101159673DSN1 component of MIS12 kinetochore complex. (381 aa)
dclre1bDNA cross-link repair 1B. (582 aa)
atrxATRX chromatin remodeler. (2095 aa)
kntc1Kinetochore associated 1. (1989 aa)
cenptCENP-T_C domain-containing protein. (866 aa)
ndc80NDC80 kinetochore complex component. (640 aa)
cenpqUncharacterized protein. (289 aa)
mtbpMDM2 binding protein. (882 aa)
cenplCentromere protein L. (353 aa)
LOC101156724WD repeat, sterile alpha motif and U-box domain containing 1. (474 aa)
LOC101155061Baculoviral IAP repeat containing 5a. (141 aa)
LOC101157951Si:dkey-6i22.5. (229 aa)
LOC101155373Biorientation of chromosomes in cell division 1. (167 aa)
cenpiCentromere protein I. (731 aa)
LOC101161885Si:ch211-220i18.4; Belongs to the protein kinase superfamily. (419 aa)
hellsHelicase, lymphoid specific. (853 aa)
ten1TEN1 subunit of CST complex. (132 aa)
kmt5bLysine methyltransferase 5B. (864 aa)
H2L4M6_ORYLAUncharacterized protein. (160 aa)
pot1Protection of telomeres 1 homolog. (812 aa)
LOC101155136Mix-type homeobox gene 1. (299 aa)
spc25SPC25 component of NDC80 kinetochore complex. (237 aa)
CBX1Uncharacterized protein. (182 aa)
WDSUB1WD repeat, sterile alpha motif and U-box domain containing 1. (481 aa)
fam43bFamily with sequence similarity 43 member B. (305 aa)
bub1BUB1 mitotic checkpoint serine/threonine kinase. (1115 aa)
nsl1NSL1 component of MIS12 kinetochore complex. (261 aa)
spc24SPC24 component of NDC80 kinetochore complex. (199 aa)
ENSORLP00000033799Uncharacterized protein. (799 aa)
LOC101160375Uncharacterized protein. (544 aa)
smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a. (1621 aa)
sirt6Sirtuin 6. (347 aa)
ckap5Cytoskeleton associated protein 5. (1640 aa)
zw10Zw10 kinetochore protein. (767 aa)
LOC101159187Protein kinase domain-containing protein. (578 aa)
mettl24Methyltransferase like 24. (364 aa)
LOC101170809Uncharacterized protein. (1282 aa)
ska3Spindle and kinetochore associated complex subunit 3. (591 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.