(14 nodes) ATP-grasp fold, subdomain 1 network (Oryzias latipes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101174347	Synapsin IIa. (467 aa)
	acacb	Acetyl-CoA carboxylase beta. (2377 aa)
	LOC101161357	Uncharacterized protein. (528 aa)
	LOC101155873	Acetyl-CoA carboxylase alpha. (2092 aa)
	pcca	Propionyl-CoA carboxylase subunit alpha. (714 aa)
	LOC101163826	Synapsin I. (631 aa)
	sucla2	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (466 aa)
	cps1	Carbamoyl-phosphate synthase 1, mitochondrial. (1515 aa)
	mccc1	Methylcrotonoyl-CoA carboxylase 1 (alpha). (717 aa)
	suclg2	Succinate-CoA ligase, GDP-forming, beta subunit. (363 aa)
	rimklb	Ribosomal modification protein rimK-like family member A. (423 aa)
	syn2	Uncharacterized protein. (813 aa)
	gart	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1007 aa)
	pc	Pyruvate carboxylase b. (1048 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101155873	acacb	ENSORLP00000012551	ENSORLP00000009716	Acetyl-CoA carboxylase alpha.	Acetyl-CoA carboxylase beta.	0.901
LOC101155873	cps1	ENSORLP00000012551	ENSORLP00000020044	Acetyl-CoA carboxylase alpha.	Carbamoyl-phosphate synthase 1, mitochondrial.	0.408
LOC101155873	gart	ENSORLP00000012551	ENSORLP00000007887	Acetyl-CoA carboxylase alpha.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.890
LOC101155873	mccc1	ENSORLP00000012551	ENSORLP00000026750	Acetyl-CoA carboxylase alpha.	Methylcrotonoyl-CoA carboxylase 1 (alpha).	0.540
LOC101155873	pc	ENSORLP00000012551	ENSORLP00000006680	Acetyl-CoA carboxylase alpha.	Pyruvate carboxylase b.	0.608
LOC101155873	pcca	ENSORLP00000012551	ENSORLP00000000447	Acetyl-CoA carboxylase alpha.	Propionyl-CoA carboxylase subunit alpha.	0.540
LOC101155873	sucla2	ENSORLP00000012551	ENSORLP00000017629	Acetyl-CoA carboxylase alpha.	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.852
acacb	LOC101155873	ENSORLP00000009716	ENSORLP00000012551	Acetyl-CoA carboxylase beta.	Acetyl-CoA carboxylase alpha.	0.901
acacb	cps1	ENSORLP00000009716	ENSORLP00000020044	Acetyl-CoA carboxylase beta.	Carbamoyl-phosphate synthase 1, mitochondrial.	0.408
acacb	gart	ENSORLP00000009716	ENSORLP00000007887	Acetyl-CoA carboxylase beta.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.890
acacb	mccc1	ENSORLP00000009716	ENSORLP00000026750	Acetyl-CoA carboxylase beta.	Methylcrotonoyl-CoA carboxylase 1 (alpha).	0.540
acacb	pc	ENSORLP00000009716	ENSORLP00000006680	Acetyl-CoA carboxylase beta.	Pyruvate carboxylase b.	0.608
acacb	pcca	ENSORLP00000009716	ENSORLP00000000447	Acetyl-CoA carboxylase beta.	Propionyl-CoA carboxylase subunit alpha.	0.540
acacb	sucla2	ENSORLP00000009716	ENSORLP00000017629	Acetyl-CoA carboxylase beta.	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.852
cps1	LOC101155873	ENSORLP00000020044	ENSORLP00000012551	Carbamoyl-phosphate synthase 1, mitochondrial.	Acetyl-CoA carboxylase alpha.	0.408
cps1	acacb	ENSORLP00000020044	ENSORLP00000009716	Carbamoyl-phosphate synthase 1, mitochondrial.	Acetyl-CoA carboxylase beta.	0.408
cps1	gart	ENSORLP00000020044	ENSORLP00000007887	Carbamoyl-phosphate synthase 1, mitochondrial.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.888
gart	LOC101155873	ENSORLP00000007887	ENSORLP00000012551	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	Acetyl-CoA carboxylase alpha.	0.890
gart	acacb	ENSORLP00000007887	ENSORLP00000009716	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	Acetyl-CoA carboxylase beta.	0.890
gart	cps1	ENSORLP00000007887	ENSORLP00000020044	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	Carbamoyl-phosphate synthase 1, mitochondrial.	0.888