STRINGSTRING
LOC101162149 LOC101162149 six2 six2 six3-2 six3-2 six6 six6 six1 six1 six4 six4 six3 six3 LOC101175353 LOC101175353 LOC101162386 LOC101162386
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101162149SIX homeobox 9. (220 aa)
six2SIX homeobox 2a. (290 aa)
six3-2Homeobox protein SIX3. (323 aa)
six6SIX homeobox 6a. (245 aa)
six1SIX homeobox 1a. (284 aa)
six4SIX homeobox 4a. (680 aa)
six3Homeobox protein SIX3; Transcriptional regulator which can act as both a transcriptional repressor and activator by binding a ATTA homeodomain core recognition sequence on these target genes. During forebrain development represses WNT1 expression allowing zona limitans intrathalamica formation and thereby ensuring proper anterio-posterior patterning of the diencephalon and formation of the rostral diencephalon. Acts as a direct upstream activator of SHH expression in the rostral diencephalon ventral midline and that in turn SHH maintains its expression. In addition, Six3 activity is re [...] (272 aa)
LOC101175353SIX homeobox 7. (259 aa)
LOC101162386SIX homeobox 5. (928 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (20%) [HD]